A blood purification apparatus that includes a blood circuit including an arterial blood circuit and a venous blood circuit and through which blood of a patient is allowed to extracorporeally circulate; a blood purification unit connected to and provided between the arterial blood circuit and the venous blood circuit and that purifies the blood flowing through the blood circuit; a blood pump provided to the arterial blood circuit and that delivers the blood of the patient from a distal end of the arterial blood circuit to a distal end of the venous blood circuit; a substitution line through which a substitution fluid is allowed to be introduced into the blood circuit; and an infusion portion attached to the substitution line and from which a predetermined liquid drug to be administered to the patient is allowed to be infused into the substitution line. The blood purification apparatus includes a control unit that executes a drug introduction mode in which the substitution fluid in the substitution line is introduced into the blood circuit, the control unit causing the liquid drug infused from the infusion portion in the drug introduction mode to be introduced into the blood circuit together with the substitution fluid; and a calculation unit that calculates a volume of the substitution fluid introduced from the substitution line into the blood circuit with the execution of the drug introduction mode.

A blood purification apparatus that includes a blood circuit including an arterial blood circuit and a venous blood circuit and having a flow route that allows a patient's blood to extracorporeally circulate from a distal end of the arterial blood circuit to a distal end of the venous blood circuit; a blood purifier connected to a proximal end of the arterial blood circuit and to a proximal end of the venous blood circuit and that purifies the blood flowing through the blood circuit; an air-trap chamber connected to the blood circuit and that traps bubbles contained in liquid flowing in the flow route of the blood circuit; and a blood pump provided to the arterial blood circuit and being capable of delivering the liquid within the blood circuit. An upstream bubble-detecting unit attached to a position of the blood circuit on an upstream side with respect to the air-trap chamber and that detects bubbles contained in the liquid flowing in the blood circuit; and a control unit that reduces, at the detection of any bubbles by the upstream bubble-detecting unit, a flow rate of the liquid flowing into the air-trap chamber.

Disclosed are hemodialysis and similar dialysis systems including fluid flow circuits. Hemodialysis systems may include a blood flow path, and a dialysate flow path including balancing, mixing, and/or a directing circuits. Preparation of dialysate may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit and/or the various fluid flow paths may be isolated from electrical components. A gas supply may be provided that, when activated, is able to urge dialysate through the dialyzer and blood back to the patient. Such a system may be useful during a power failure. The hemodialysis system may also include fluid handling devices, such as pumps, valves, mixers, etc., actuated using a control fluid. The control fluid may be delivered to the fluid handling devices using a detachable external pump. The fluid handling devices may have a spheroid shape with a diaphragm dividing it into two compartments.

A hydrophobic filter for filtering an airflow or another gaseous flow in a medical application comprises a housing encompassing a filter chamber, an inlet port arranged on the housing and forming an inlet opening, an outlet port arranged on the housing and forming an outlet opening, and a hydrophobic structure extending along a plane of extension and separating the filter chamber into an inlet chamber and an outlet chamber. The inlet opening opens into the inlet chamber and the outlet opening opens into the outlet chamber. Herein, the outlet opening opens into the outlet chamber at a first location when viewed along the plane of extension and the inlet opening opens into the inlet chamber at a second location different from the first location when viewed along the plane of extension.

A blood purification apparatus that is capable of performing a liquid spill prevention operation and uniformizing the amount of air introduced through an opened portion. The blood purification apparatus includes a dialysate introduction line that allows dialysate to be introduced into a dialyzer; a dialysate discharge line that allows the dialysate to be discharged from the dialyzer; coupling tools that allow free switching between a connected state which causes a closed circuit, and an opened state which causes the closed circuit to be opened to form an opened portion; and a control means that performs a liquid spill prevention operation in which external air is introduced through the opened portion. An air detection means, by which air introduced through the opened portion is detectable, is provided in the vicinity of the coupling tools, and the control means stops the liquid spill prevention operation when air is detected by the air detection means.

An air trap chamber is provided with a cap and a housing. The cap has an inlet port provided at one end, and has, at another end, a first connection flange provided so as to have an inner circumferential surface. An opening axis of the inlet port is set so as to be off a center axis of the inner peripheral surface. The housing has, at one end, a second connection flange provided so as to have an outer circumferential surface which is mated to the inner circumferential surface, and has an outlet port provided at another end. An opening axis of the outlet port is set so as to be off the center axis of the outer circumferential surface. Moreover, parting lines which are positioning structures are provided on the cap and the housing, respectively.

The present disclosure is a machine that permits intra-corporeal dialysis, which machine may be carried by the patient and include a canister of dialysate and a small pump. Filtration of toxins from blood takes place in the patient's own blood stream via a catheter. The catheter is inserted into a major blood vein. Dialysate is pumped from a first end of a canister into the central channel of the catheter. At the other end of the catheter, the dialysate passes to an annular region and reverses direction. The exterior wall of the exterior region of the catheter is permeable to blood, but not to the dialysate. Blood passes through the exterior wall of the catheter and is exposed to the dialysate in the annular region. There the dialysate absorbs toxins before it returns to the second side of the canister.

An apparatus for extracorporeal treatment of blood (1) comprising a filtration unit (2), a blood withdrawal line (6), a blood return line (7), an effluent fluid line (13), a pre and/or post-dilution fluid line (15, 25) connected to the blood withdrawal line, and a dialysis fluid line. Pumps (17, 18, 21, 22, 27) act on the fluid lines for regulating the flow of fluid. A control unit (10) is configured to periodically calculate a new value for the patient fluid removal rate to be imposed on an ultrafiltration actuator in order to keep a predefined patient fluid removal rate across a reference time interval irrespective of machine down times.

A blood purification apparatus that is capable of, with no preparatory operations, performing substitution by supplying dialysate in a dialysate introduction line to a blood circuit during ultrafiltration treatment, or performing blood return by immediately supplying the dialysate in the dialysate introduction line to the blood circuit after the ultrafiltration treatment. A blood purification apparatus includes a dialyzer, a dialysate introduction line, a dialysate drain line L2 through which drain liquid from the dialyzer is drained, and an ultrafiltration pump capable of removing water from the blood in the blood circuit. The blood purification apparatus is capable of performing substitution or blood return by supplying the dialysate in the dialysate introduction line L1 to the blood circuit. In an ultrafiltration treatment in which the ultrafiltration pump is activated while the introduction of the dialysate into the dialyzer is stopped, dialysate delivery is performed while the introduction of the dialysate into the dialyzer is prevented.

An adapter set that is attached to artery-side and vein-side shunt connectors-that are provided on a blood circuit. The adapter set includes: an artery-side adapter that has one end thereof connected to the artery-side shunt connector, has the other end thereof connected to a drainage port that is provided on the outside of the blood circuit, and thereby connects the artery-side shunt connector and the drainage port fluid tight; and a vein-side adapter that has one end thereof connected to the vein-side shunt connector, has the other end thereof connected to a supply port that is provided on the outside of the blood circuit, and thereby connects the vein-side shunt connector and the supply port fluid tight. The structure of the other end of the artery-side adapter and the structure of the other end of the vein-side adapter are different.