The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.

A dialysis machine includes a dialyzer (1), a dialysate feed system (5) having a feed line (52), and a discharge system (6) having a discharge line (62). The machine further includes ultrafiltration control elements (UF) and back-filtration control elements (RF). The feed line is provided with a constriction (520) and with elements for measuring the pressure difference (523, 524) across the terminals of the constriction. The feed system further includes a ventricle bag (50), and pressurizer elements (70) for putting the ventricle bag (50) under pressure. The machine further includes an open/close system (C5, C5′) for opening/closing the discharge line (62) and the back-filtration control elements cause the discharge line (62) to close, and control the pressure applied to the ventricle bag (50), as a function of the pressure difference measured across the terminals of the constriction (520), so as to obtain a given flow rate of dialysate.

A method and a system are provided for detecting a condition indicative of a dislodged needle in a hemodialysis procedure. A venous return pressure for a patient undergoing dialysis is measured. The venous return pressure is analyzed via a controller, and an intravascular blood pressure in proximity to a location of needle insertion into the patient is derived. A lower limit is calculated as a function of the intravascular blood pressure via the controller. An average of the venous return pressure is calculated via the controller during a predetermined time window. The average is compared to the lower limit via the controller, and if the average is within a specified range of the lower limit, the controller determines that a condition indicative of a dislodged needle is present.

Pressure measurement system (e.g., for an extracorporeal treatment system), method and pressure pod apparatus including a position sensor for use in repositioning a diaphragm that separates a liquid side cavity from a transducer side cavity (e.g., operatively connected to a pressure transducer); the liquid side cavity being in fluid communication with an inlet and an outlet.

A pressure output device (POD) assembly for sensing fluid pressure in a fluid processing system, is provided. This POD assembly includes a shell defining a shell interior, and a movable diaphragm disposed in the shell interior and separating the shell interior into a flow-through chamber and a pressure sensing side. A sensor port is in fluid communication with the pressure sensing side. An inlet port and an outlet port are in fluid communication with the flow-through chamber. The inlet port and the outlet port define an inlet and an outlet, respectively, of a flow-through channel that passes through the flow-through chamber. A boss protrudes from the interior wall of the shell and extends into the flow-through channel to prevent occlusion of flow under different pressure conditions within the flow-through chamber.

A pressure sensing device includes a case provided on a liquid flow path through a liquid, a diaphragm that is provided so as to divide a space in the case into a first space with the liquid flowing therethrough and a second space filled with a gas, a pressure sensor to measure pressure of the gas, and a diaphragm initial position adjustment mechanism capable of adjusting an initial position of the diaphragm to a desired position. The diaphragm initial position adjustment mechanism includes a reciprocating pump that includes a cylinder in communication with the second space, a plunger provided so as to be able to advance and retract within the cylinder, and a plunger driving part to advance and retract the plunger, and adjusts a filling amount of the gas filling the second space by advancing and retreating the plunger in the cylinder by the plunger driving part.

Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy.

The present invention relates to a method and to an apparatus for continuously monitoring the membrane coupling in a pressure measurement system in a extracorporeal circuit of a blood treatment machine. The invention enables the continuous monitoring of the functionality of the pressure measurement system without an interruption of any blood treatment being necessary.

A biomedical joint device for the measurement of physical quantities comprises one tubular joint element provided with at least one connecting channel defining a first port, connectable to a biomedical device for the treatment of a body fluid, and a second port opposite to the first port; a sensor means, positioned adjacent to the second port and communicating with the connecting channel, adapted to detect at least one physical quantity characteristic of the body fluid; and one supporting element of the sensor associated with the joint element, to close said second port.

An extracorporeal blood treatment machine includes a blood treatment device, a conveying device for conveying blood through the blood treatment device, and a connection mask designed to interchangeably receive a tube set in a predefined arrangement. The tube set has pressure-monitoring lines that branch off from the tube set and can be connected to pressure sensor connections located on the connection mask. The pressure sensor connections are spaced apart and positioned so as to match the tube set such that, when the tube set is mounted in the predefined arrangement on the connection mask, each pressure-monitoring line, owing to its limited length and the predefined arrangement of the associated branch on the blood treatment machine, can be connected exclusively to only one of the pressure sensor connections. A corresponding tube set is used with the extracorporeal blood treatment machine.