A fill adapter for filling a reservoir and a related method are disclosed herein. The fill adapter includes a button assembly actuator and a pump chamber plunger actuator hingeably attached to the button assembly actuator, wherein the actuation of the button assembly actuator actuates the pump chamber plunger actuator and wherein the pump chamber plunger actuator actuates a pump chamber membrane before the at least one button assembly is actuated.

A method of dispensing a therapeutic fluid from a line includes providing an inlet line connectable to an upstream fluid source. The inlet line is in downstream fluid communication with a pumping chamber. The pumping chamber has a pump outlet. The method also includes actuating a force application assembly so as to restrict retrograde flow of fluid through the inlet while pressurizing the pumping chamber to urge flow through the pump outlet. A corresponding system employs the method.

A fluid delivery apparatus includes controller hardware, a diaphragm pump, a positive displacement pump, and a fluid conduit extending between the diaphragm pump and the positive displacement pump. During operation, and delivering fluid to a downstream recipient, the controller hardware draws fluid into a chamber of the diaphragm pump from a fluid source container. The controller hardware applies pressure to the chamber of the diaphragm pump to output the fluid in the chamber of the diaphragm pump downstream through the fluid conduit to the positive displacement pump. During application of the pressure to the chamber and outputting the fluid in the chamber of the diaphragm pump downstream, the controller hardware activates the positive displacement pump to pump the fluid from the positive displacement pump to the downstream recipient.

An infusion pump can determine and display what the drug load is inside of a patient by taking into account various factors such as drug half-life, pump pauses, and delays while a drug moves from a pump to a patient. A pump can also calculate and provide times when: medication will reach the patient; the drug concentration will reach a specified level; and a physiological response is expected. The pump can compensate for pauses in the delivery—for example, by infusing larger boluses of the drug into the patient within safe boundaries for concentration and timing. The pump can also predict what the drug load or concentration will be in the patient over time after the infusion stops by providing a graph, and in some cases act on such predictions by changing a flow rate or other parameters.

An infusion pump including a fluid chamber having an outlet valve and a piezo-stack actuator including a stack of piezo-electric layers. The infusion pump also includes a linear actuator to measure displacement of the piezo-stack actuator during operation. An electronic processor is programmed to operate the outlet valve and the piezo-stack actuator to pump fluid through the fluid chamber at a programmed flow rate.

A system for at least partial closed-loop control of a medical condition is disclosed. The system includes at least one medical fluid pump. The medical fluid pump including a sensor for determining the volume of fluid pumped by the pump. Also, at least one continuous analyte monitor, and a controller. The controller is in communication with the medical fluid pump and the at least one continuous analyte monitor. The controller includes a processor. The processor includes instructions for delivery of medical fluid based at least on data received from the at least one continuous analyte monitor.

Methods and devices for accurately pumping small quantities of liquid to a patient with a broad range of flow and low cost.

In one embodiment, a fluid storage device includes a rigid outer housing that defines a septum cavity, a reservoir cavity, and a channel that extends between the two cavities, the outer housing further defining an outlet in fluid communication with the reservoir cavity, a septum provided within the septum cavity, the septum being made of an elastic polymer and facilitating refilling of the fluid storage device, and a thin, collapsible membrane that does not generate significant restoring forces when it is deformed as fluid is drawn from the reservoir cavity and, therefore, does not completely or partially return to its initial non-deformed shape even if the outlet of the device remains open after doses are administered.

Methods and devices for accurately pumping small quantities of liquid to a patient with a broad range of flow and low cost.

An infusion pump (10) includes a fluid chamber (28) having an outlet valve (34) and a piezo-stack actuator (36) comprising a stack of piezo-electric layers (38). An electronic processor (18) is programmed to operate the outlet valve and the piezo-stack actuator to pump fluid through the fluid chamber at a programmed flow rate.