The invention features a drug delivery device held in the mouth and continuously administering either a fluid comprising drug dissolved and/or dispersed in water or in a non-toxic liquid, or a drug in solid form.

An infusion system for subcutaneous delivery of a fluid to a subject is disclosed. The infusion system comprises a source of a fluid; a fluid delivery system; a first fluid conduit in fluid communication with the source of the fluid and the fluid delivery system; a fluid injection device configured to be inserted into the skin of a subject for delivering the fluid to the subject; a second fluid conduit in fluid communication with the fluid delivery system and the fluid injection device; and a support frame attached to the source of the fluid and the fluid delivery system, wherein the support frame is configured to mount the source of the fluid and the fluid delivery system on a region of a head of the subject. The fluid delivery system moves the fluid from the source of the fluid, through the first fluid conduit, through the second fluid conduit, and through the fluid injection device.

An infusion device (3) for administering a medical fluid to a patient, comprises a housing (30) and a receptacle (300) arranged on the housing (30) for receiving a syringe (4), the syringe (4) having a barrel (41) for containing a medical fluid and a plunger (42) movable relative to the barrel (41) for delivering the medical fluid out of the barrel (41). A pusher device (32) is movable relative to the housing (30) for acting onto the plunger (42) for moving the plunger (42) relative to the barrel (41), and a drive mechanism (38) drives the pusher device (32). A coupling mechanism (36, 37) is operative to couple the plunger (42) to the pusher device (32) or to couple the pusher device (32) to the drive mechanism (38), and an actuation mechanism arranged on the pusher device (32) comprises an actuation element (33) for actuating the coupling mechanism (36, 37) between a coupling state and an uncoupling state. Herein, the actuation mechanism comprises a first threaded element (34) rotatable about a rotational axis (342) and a second threaded element (331) movable along the first threaded element (34), the second threaded element (331) being in threaded engagement with the first threaded element (34) such that the first threaded element (34) is rotated when the second threaded element (331) is moved along the first threaded element (34), wherein the actuation element (33) is actuatable to move the second threaded element (331) along the first threaded element (34), the first threaded element (34) being operatively connected to the coupling mechanism (36, 37). In this way an infusion device is provided which in an easy and comfortable manner allows a user to actuate a coupling mechanism, in particular for installing a syringe on a receptacle of the infusion device.

A pump including: a stator (4), a rotor (6) slidably and rotatably mounted at least partially in the stator, the rotor comprising a first axial extension (24) having a first diameter (D1) and a second axial extension (26) having a second diameter (D2) greater than the first diameter, a first valve (V1) formed by a first valve seal (18) mounted on the stator around the first axial extension, in conjunction with a first channel (42) in the rotor that is configured to allow liquid communication across the first valve seal when the first valve is in an open position, a second valve (V2) formed by a second valve seal (20) mounted on the stator around the second axial extension, in conjunction with a second channel (44) in the rotor that is configured to allow liquid communication across the second valve seal when the second valve is in an open position, and a pump chamber (8) formed between the rotor and stator and between the first valve seal and second valve seal. The pump further comprises a priming actuator (30) mounted on a housing of the stator and movable from a locked operating position to a priming position, the priming actuator (30) configured to engage and axially displace the rotor from an operating position in which at least one of the first and second valves is closed, to a priming position in which both first and second valves are open.

Syringe control assemblies are described herein. A syringe control assembly includes an assembly body, a first syringe, a second syringe, and a pump assembly. The first and second syringes are releasably coupled to a syringe mounting rack of the assembly body. The pump assembly includes a first pump unit and a second pump unit. Each pump unit is in fluid communication with each respective syringe. In a priming configuration, the first pump unit is configured to draw fluid flow from the first syringe cavity and the second pump unit is configured to pump fluid flow into the second syringe cavity.

Disclosed are systems and processes for an optical monitoring system for monitoring the dispensing of fluid from a fluid delivery device For example, a fluid delivery device may include a reservoir storing a fluid, a pump fluidically coupled to the reservoir, the pump comprising a drive mechanism to force the fluid from the reservoir, and an optical monitoring system. The optical monitoring system may include at least one light source operative to emit light incident on at least one element of the drive mechanism, and at least one sensor configured to receive the light reflecting off of the at least one element, wherein the at least one light source and the at least one sensor are arranged on a same side of the at least one element. Other embodiments are described.

A syringe pump is provided. The syringe pump includes a pump body, a control system, a transmission mechanism, and a propulsion mechanism. The transmission mechanism includes a bracket, a propulsion driving motor, a screw rod, a sliding seat, a half nut, and a clutch driving assembly. The propulsion driving motor configured to drive the screw rod to rotate, the clutch driving assembly is disposed on the sliding seat, and configured to drive the half nut and the screw rod to be engaged and disengaged from each other. The propulsion mechanism includes a connecting rod, a pushing block, a pressure sensing assembly, and a clutch switch. The pressure sensing assembly is disposed on the pushing block and configured to detect pressure of a piston rod of a syringe. The clutch switch is disposed on the pushing block and electrically connected to the clutch driving assembly.

A pump including: a stator (4), a rotor (6) slidably and rotatably mounted at least partially in the stator, the rotor comprising a first axial extension (24) having a first diameter (D1) and a second axial extension (26) having a second diameter (D2) greater than the first diameter, a first valve (V1) formed by a first valve seal (18) mounted on the stator around the first axial extension, in conjunction with a first channel (42) in the rotor that is configured to allow liquid communication across the first valve seal when the first valve is in an open position, a second valve (V2) formed by a second valve seal (20) mounted on the stator around the second axial extension, in conjunction with a second channel (44) in the rotor that is configured to allow liquid communication across the second valve seal when the second valve is in an open position, and a pump chamber (8) formed between the rotor and stator and between the first valve seal and second valve seal.

The pump further comprises a priming actuator (30) mounted on a housing of the stator and movable from a locked operating position to a priming position, the priming actuator (30) configured to engage and axially displace the rotor from an operating position in which at least one of the first and second valves is closed, to a priming position in which both first and second valves are open.

A nerve cuff for establishing a nerve block on a nerve can have a cuff body with a channel for receiving a nerve, a reservoir for holding a drug, and an elongate opening slit extending the length of the cuff body that can be opened to provide access to the channel and can be closed to enclose the cuff body around the nerve. The nerve cuff can also include an electrode for detecting and measuring electrical signals generated by the nerve. A controller can be used to control delivery of the drug based on the electrical signals generated by the nerve.

A syringe pump includes a lead screw, a motor, and a sliding block assembly. The lead screw has threads and the motor is coupled to the lead screw to rotate it. The half-nut housing has a half nut and a barrel cam. The half nut is disposed within the half-nut housing. The half nut has half-nut threads at an end adjacent to the lead screw void. The half nut engages or disengages with the threads of the lead screw. The half nut includes a half-nut cam-follower surface and a half nut slot. The barrel cam is disposed within the half-nut housing and engages with the half-nut cam-follower surface. The barrel cam includes a pin to fit within the half nut slot such that the barrel cam rotates between a first position and a second position to actuate the half nut between the engagement position and the disengagement position, respectively.