A method of dispensing a therapeutic fluid from a line includes providing an inlet line connectable to an upstream fluid source. The inlet line is in downstream fluid communication with a pumping chamber. The pumping chamber has a pump outlet. The method also includes actuating a force application assembly so as to restrict retrograde flow of fluid through the inlet while pressurizing the pumping chamber to urge flow through the pump outlet. A corresponding system employs the method.

A device for targeted delivery of a substance to an airway may include a conduit and at least two applicators. The conduit may include a proximal end and a bifurcated distal portion having two distal ends. Each applicator may be coupled with one of the distill ends of the conduit and may be configured to direct the substance out of the applicator toward one of two sides of an airway. A method for targeted delivery of a substance to an airway may involve advancing a substance delivery device into the airway, contacting two sides of the airway with at least two applicators of the substance delivery device, such that each applicator contacts the airway near a glossopharyngeal nerve and/or a superior laryngeal nerve on each of the two sides of the airway, and delivering the substance through the applicators to contact the airway along the two sides.

An infusion device for the passage of fluids to or from a patient via a syringe. The infusion device includes a valve assembly and a coupling apparatus. The coupling apparatus comprises a coupler, a first gland, a cannula, a second gland, and an inlet. The coupling apparatus defines a central lumen for the passage of fluids in an open configuration. The inlet may be coupled to a syringe.

The present application provides a self-powered drug-delivery device. The device includes a chamber having a wall. The chamber contains a fluid and is in connection with an administration means. The device also includes a displacement-generating battery cell. The device further includes an electrically-controlled battery unit, which includes the displacement-generating battery cell coupled to the chamber by a coupling means. The displacement-generating battery cell includes an element that changes shape as a result of charge or discharge of the battery cell so as to cause a displacement within the battery unit. The arrangement of the battery unit, the coupling means, the wall, the chamber, and the administration means is such that the displacement derived from the battery unit is conveyed by the coupling means to cause displacement of the wall of the chamber such that the fluid is expelled from the chamber to force a drug towards the administration means.

According to aspects disclosed herein, an infusion lead assembly may include a housing including a needle receptacle, a housing lumen, a pin receptacle, and a housing conductive trace; a connector including an connector needle, an internal lumen, a metal pin, and a connector conductive trace, and an infusion lead body including an infusion lumen, an exit port, an internal wire, and a distal electrode. The infusion lead assembly may form an electrical path to transmit electrical signals across the connector conductive trace, the metal pin, the housing conductive trace, the internal wire, and the distal electrode. The infusion lead assembly may form a fluid path to transmit fluid across the internal lumen, the connector needle, the infusion lumen, and the exit port.

A fluid delivery system is disclosed which comprises at least one supply station for supplying at least one fluid, a pressurizing unit for pressurizing said at least one fluid, an inlet fluid circuit in fluid communication with said at least one supply station and with a pump module of said pressurizing unit and an outlet fluid circuit in fluid communication with said pump module for discharging the fluid from the chamber. The chamber is provided with a piston reciprocating therein, thereby defining first and second variable-volume sub-chambers. The fluid delivery system further comprises a recirculation fluid circuit fluidically connecting said first and second variable-volume sub-chambers, and an actuator associated to said recirculation fluid circuit for managing the passage of said at least one fluid between said first and second variable-volume sub-chambers in both directions. A method of operating the fluid delivery system is also disclosed.

A device and method for measuring a volume of liquid expelled from a syringe is provided. The device generally includes a syringe barrel, a plunger actuated with a plunger rod, and a sensor. The sensor may include two ports with one port being in fluid communication with a source of fluid external to the syringe barrel, while the second port is in fluid communication either with a proximal end portion of the syringe barrel or a hollow plunger rod having a first end closed by the plunger. The method may include expelling liquid from the syringe; detecting and recording differential pressure with the sensor over time; and calculating the volume of liquid expelled from the syringe from the recorded differential pressure over time.

The present disclosure relates to a test device to be inserted into the syringe receptacle of a pump, for example for a blood treatment apparatus, for testing at least one function of the pump and/or of the blood treatment apparatus. The test device includes a holding device for releasably holding the test device on the housing of the blood treatment apparatus. In addition, the test device includes at least one movable actuator and at least one electric motor arranged to directly or indirectly move said movable actuator or a section thereof.

A method for performing a medical procedure requiring effective, reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient includes providing a compressed gas cylinder having a weight with medical grade gas sealed therein of at least twelve grams and not greater than fifty grams. The method also includes connecting the compressed gas cylinder to an integrated compressed gas unit including a regulator valve assembly positioned between an outlet port and an inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial. A flow control system is secured to the compressed gas unit and the medical grade gas is delivered in precisely controlled amounts by actuating the compressed gas unit and operating the flow control system to deliver the medical grade gas to vasculature of the patient.

Described herein are systems and methods for performing peritoneal dialysis. According to one aspect, the disclosure provides a sterile interface connection for connecting a water purification system to a disposable source of dialysate concentrates. The sterile interface connection can include a chamber comprising an inlet adapted to be connected to the water purification system on a proximal end and a valve on a distal end. The sterile interface connection can also include spring-loaded needle disposed in the chamber. The spring-loaded needle can move between a retracted configuration in which the spring-loaded needle is fully retracted into the chamber and the valve is closed and sealed, and an extended configuration in which the spring-loaded needle extends through the valve into the disposable source of dialysate concentrates.