An infusion pump (10) includes a fluid chamber (28) having an outlet valve (34) and a piezo-stack actuator (36) comprising a stack of piezo-electric layers (38). An electronic processor (18) is programmed to operate the outlet valve and the piezo-stack actuator to pump fluid through the fluid chamber at a programmed flow rate.

Disclosed herein are systems and methods for monitoring performance of an ambulatory infusion pump. An ambulatory infusion pump can include a reservoir configured to contain a medicament including a plunger at a proximal end of the reservoir and an outlet port at a distal end of the reservoir. A motor can be configured to cause linear motion of a pushrod to contact and move the plunger to cause medicament to flow from the reservoir out of the outlet port to a patient. An optical encoder can be employed to monitor a linear position of the pushrod. In addition, the optical encoder can be employed to monitor additional system conditions and/or a secondary encoder can be employed to monitor the performance of the optical encoder.

A drug solution administration device includes a drug solution reservoir, a drive unit, a rotation detection unit, and a control unit. The control unit counts the number of rotations of the drive unit from when a rotation sensor value reaches a blockage start threshold value until the rotation sensor value reaches a blockage detection threshold value. Further, the control unit determines that a blockage of a flow path has occurred when the rotation sensor value reaches the blockage detection threshold value, and rotates the drive unit in a direction opposite to a direction in which the drug solution is administered based on the counted number of rotations.

Devices, systems, and methods are provided herein for delivering medication (e.g., insulin) via a wearable pump having a patch-style form factor for adhesion to a user's body. The reusable pump may be coupled to a disposable cap housing a microdosing system for delivering precise, repeatable doses of medication to a cannula configured to deliver medication to a target infusion area beneath the user's outer skin layer. The system further may include an applicator for inserting the cannula into the user's skin and/or applying an adhesive pad to the skin.

A method of adjusting a pressure distribution within an administration set to minimize an inadvertent delivery of a large bolus of infusate upon a sudden release of the occlusion, while ensuring that a maximum safe pressure limitation of the administration set is not exceeded.

An apparatus, method, and system for detecting a leaking occluder valve is disclosed. Upper and lower occluder elements of an infusion pump are activated to compress a fluid tubing filled with a fluid to isolate the fluid in an upstream portion of the tubing from a downstream portion of the tubing. While the fluid tubing is compressed by the occluder elements, a pumping element of the infusion pump is activated to compress an intermediate portion of the tubing, between the downstream portion and the upstream portion, to cause a pressure increase within the fluid tubing. Using at least one pressure sensor, a determination is made as to whether the pressure increase is present in a portion of the fluid tubing on a side, of an activated occluder element, opposite the intermediate portion of the tubing.

Devices, systems, and methods are provided herein for delivering medication (e.g., insulin) via a wearable pump having a patch-style form factor for adhesion to a user's body. The reusable pump may be coupled to a disposable cap housing a microdosing system for delivering precise, repeatable doses of medication to a cannula configured to deliver medication to a target infusion area beneath the user's outer skin layer. The system further may include an applicator for inserting the cannula into the user's skin and/or applying an adhesive pad to the skin.

The present invention provides a microfluidic pump-based infusion anomaly state detection and control system, comprising: a microfluidic pump chip configured to control the vibration of an actuating device to output a liquid; a pressure sensor located in a pipeline behind the outlet of the microfluidic pump chip and configured to sense the change of the pressure of the liquid output by the microfluidic pump chip to output an electric signal; a signal conditioning circuit configured to perform signal conditioning on the electric signal to obtain a conditioned electric signal; a signal acquisition circuit configured to convert the conditioned electric signal from an analog signal into a digital signal; a signal processing unit configured to determine the working state of the microfluidic pump chip and the working state of an infusion pipeline according to the digital signal, and to send a signal to an alarming unit when an anomaly is found; the alarming unit configured to alarm according to the signal; and a control drive unit configured to adjust the output state of the microfluidic pump chip according to the output of the signal processing unit. The present invention can precisely control a microfluidic pump chip and accurately detect the anomaly state of the microfluidic pump chip and alarm in time.

A method of dispensing fluid includes three processes. A first one of these processes includes pumping fluid into a resilient variable-volume dispensing chamber. The dispensing chamber is in series with a normally present finite fluid impedance and an output. The impedance is sufficient so as to cause expansion of the dispensing chamber as it receives pumped fluid even while some fluid flows through the output. Another one of these processes includes repeatedly measuring a parameter related to volume of the dispensing chamber over time. A third one of these processes includes controlling the pumping of fluid based on repeated measurements of the parameter to produce a desired fluid flow through the output. A corresponding system for dispensing fluid implements these processes.

A system and method is provided for detecting fluid low-volume and occlusion in a device using force sensing resistor (FSR) sensor. One or more force sensing resistors are positioned in communication with a fluid channel at one or more of a pump intake and pump outlet to detect pressure in the fluid channel. The pressure is detected through communication with the force sensing resistor and indicates an irregular system condition including but not limited to, fluid low-volume level and occlusion. Also provided are a fluid flow sensor (e.g., FSR or MEMS sensor) disposed relative to an embedded fluid channel in the base of a wearable medicine delivery pump.