A medicinal infusion system includes a safety valve for isolating residual medication by providing a single point of fluidic disconnect to encapsulate a residual fluid volume prone to spillage. The safety valve couples a medicinal repository such as an infusion pump to a medicinal supply, typically from a syringe or tubing. The safety valve includes a resilient, deformable, or hinged surface for isolating and sealing the medicinal flow to eliminate and/or isolate any residual volume in tubing and connectors. The isolating surface accommodates an inserted fitting or coupling for allowing the medicinal flow to fill the infusion pump. Upon disconnection, fluids on either side of the safety valve are therefore isolated on the respective fill or source sides, and residual volume prone to spillage is eliminated.

An apparatus, system and method for regulating fluid flow are disclosed. The apparatus includes a flow rate sensor and a valve. The flow rate sensor uses images to estimate flow through a drip chamber and then controls the valve based on the estimated flow rate. The valve comprises a rigid housing disposed around the tube in which fluid flow is being controlled. Increasing the pressure in the housing controls the size of the lumen within the tube by deforming the tube, therefore controlling flow through the tube.

Disclosed is a valve for use in a pump for a wearable drug delivery device for moving a liquid drug from reservoir into a pump chamber and thereafter from the pump chamber to a patient interface. The valve can comprise two needles, a first needle in fluid communication with the reservoir and a second needle in fluid communication with the patient interface. The first and second needles may be linearly translated to either cover the lumen opening of a needle with a septum or place the lumen opening of the needle in fluid communication with the pump chamber. When the first needle is in fluid communication with the pump chamber, the liquid drug may be transferred from the reservoir to the pump chamber via suction created by a plunger in the pump chamber. When the second needle is in fluid communication with the pump chamber, the liquid drug may be transferred from the pump chamber to the patient interface via a pressure created by the plunger in the pump chamber.

Fluid flow manifold assemblies for use in fluid flow sets are provided. The fluid flow manifold assembly includes a body having a main fluid channel and a reinforcing plate, the main fluid channel having a fluid inlet, a fluid outlet and a drug port. A flow control assembly is disposed opposite the main fluid channel from the drug port. The flow control assembly is configured to shut off fluid flow through the drug port into the main fluid channel with a plunger of the flow control assembly in a closed position and to allow incremental levels of fluid flow through the drug port into the main fluid channel by variably retracting the plunger based on rotation of a knob of the flow control assembly.

A disposable wearable micro-flow continuous drug delivery system has an elastic drug storage cavity for extruding and storing liquid drug, wherein one end of the elastic drug storage cavity is communicated with a drug outlet pipe, wherein one end of the drug outlet pipe is communicated with a first micro-flow path and a second micro-flow path for shunting liquid drug, which is far away from the elastic drug storage cavity, wherein an adjusting mechanism is connected between the first micro-flow path and a second micro-flow path, wherein a first valve and a second valve are respectively provided at the surface of the first micro-flow path and adjacent to two different sides of the adjusting mechanism, wherein the disposable wearable micro-flow continuous drug delivery system of the present invention makes the liquid drug have a certain impulse by using the elastic and soft drug storage cavity, which is convenient to inject the liquid drug into the human body, and secondly, the adjusting mechanism is set between the two micro-flow paths, and a plurality of micro valves are set on the two micro-flow paths respectively, which enable the injection volume of the liquid drug to be controlled by controlling the switches of the micro valves located at different positions to help facilitate medical treatment and minimize the effect on the daily living activity of patients.

A medicinal infusion system includes a safety valve for isolating residual medication by providing a single point of fluidic disconnect to encapsulate a residual fluid volume prone to spillage. The safety valve couples a medicinal repository such as an infusion pump to a medicinal supply, typically from a syringe or tubing. The safety valve includes a resilient, deformable, or hinged surface for isolating and sealing the medicinal flow to eliminate and/or isolate any residual volume in tubing and connectors. The isolating surface accommodates an inserted fitting or coupling for allowing the medicinal flow to fill the infusion pump. Upon disconnection, fluids on either side of the safety valve are therefore isolated on the respective fill or source sides, and residual volume prone to spillage is eliminated.

Provided herein are the safety features for radiopharmaceutical infusion system for treatment or diagnostic purpose, wherein infusion system comprises a controller, a source of radiopharmaceutical including other components. The controller is configured to perform automated quality control steps at the start of the system during daily quality control and ensure that system complies to desired technical attributes prior to administration to patients. The quality control steps comprise calibration, breakthrough testing, checking for unauthorized connection and/or malware in the system, network or other connected devices.

An on-body injector includes a drug reservoir having an outlet. First and second pistons may be positioned within the reservoir, with the second piston first being moved to open the outlet, followed by the first piston being moved to convey a drug from the reservoir via the outlet. The reservoir may instead include a cover, with a valve positioned between the outlet and the cover. The valve is rotated to place a channel of the valve in fluid communication with a through-hole of the cover, allowing flow from the reservoir via the outlet. The reservoir may instead include a valve movable from a condition in which it deforms the outlet, preventing flow through the outlet, to a condition allowing flow. The reservoir may instead include a seal that is deformed by an increase in pressure within the reservoir, with the deformed seal being open to allow flow through the outlet.

Various fluid delivery systems are described comprising an infusion pump having a housing with a first opening and a hollow interior portion that is configured to receive a cartridge having a tubing. A pump unit can be disposed within the housing. The pump unit comprises a motor mechanically coupled with a crank shaft or eccentric cam that is configured to move a set of pistons or other objects to thereby compress one or more portions of the tubing over time as the crank shaft or eccentric cam rotates.

A compact and smart wearable device is configured to automatically inject medicines into the wearer. Because hypodermic needles are only deployed when triggered, infection risks are eliminated. Necessary medicines are automatically deployed based on physiological or other data without human intervention to save lives. The wearable device can also be configured to inject more than one medicine into the wearer. And can be secured to the wearer with a band having inflatable balloons that can tighten and reposition the wearable device on the wearer