Systems and methods for delayed delivery of a drug are disclosed. A drug delivery system may include a delivery member for insertion into a patient and a reservoir configured to receive a volume of a drug. An energy source may be activatable by the patient to actuate the reservoir to deliver the drug to the patient as a single bolus. A lockout system may be configured to have a locked state, wherein the lockout system prevents movement of the delivery member and/or activation of the energy source, and an unlocked state, wherein the lockout system permits movement of the delivery member and/or activation of the energy source. The lockout system may be configured to automatically change from the locked state to the unlocked state after a preselected time period has elapsed. An output element may generate a detectable output after the preselected time period has elapsed for notifying the patient.

Injection systems comprising a powered injector and one or more hazardous agents are disclosed.

A syringe (200, 400) for use in a medication delivery device (100) comprises a vial. The vial (201, 411) comprises a chamber (206). The chamber is configured to receive a piston or plunger (205, 416). The syringe further comprises a needle attachment point (202), for the attachment of a hypodermic needle (204). The chamber is offset from the needle attachment point.

A drug delivery device configured to provide a dose of a first medicament followed by a dose of a second medicament is disclosed. The device includes a main exterior body and an interior body. The device further includes a dual-chamber reservoir with (i) a first chamber holding the first medicament and (ii) a second chamber holding the second medicament. The device also includes a needle and a plunger. After activation of the device, the plunger is configured to (i) move the dual-chamber reservoir a given distance in a distal direction with respect to the interior body so that a distal end of the needle extends out of the interior body and (ii) after moving the dual-chamber reservoir the given distance, move in the distal direction with respect to the dual-chamber reservoir so as to eject from the needle the first medicament followed by the second medicament.

A sub-assembly for medicament delivery device is presented having an engageable releasing means and a medicament delivery device including the sub-assembly, where the engageable releasing means provides force for injecting medicament contained in the device when the engageable releasing means is released. To prevent the engageable releasing means from premature release during transportation of the sub-assembly to a final assembly location a snap-fit coupling mechanism can be used to tightly hold components relevant to the release of the engageable releasing means.

A medicament delivery device is presented having a front-end device with a front-end housing and a delivery member cover that moves along a longitudinal axis between an extended position and a retracted position relative to the front-end housing, and a medicament container holder arranged in the front-end housing that receives a medicament container; and a reusable base device that is detachably connected to the front-end device, the base device has a plunger, a motor to drive the plunger inside the front-end housing, and wherein the motor drives the plunger from a second end position back to an initial end position, and a motor switch having a first switch position that changes to a default switch position by displacement of the delivery member cover when the delivery member cover is moved back from a retracted position to an extended position causing the motor to rotate in a reverse direction and drive the plunger from the second end position to the initial end position.

An injection device includes: a housing with a product container in which a stopper with a bearing face can be moved to a stopper end position and which, proximally to the stopper end position, has a minimum product container cross section; a drive configured to move the stopper, which includes a plunger rod with a drive face that contacts the bearing face; a plunger rod guide is arranged outside the product container and guides the plunger rod, with a plunger rod guide cross section adapted to a plunger rod cross section. The product container only incompletely guides movement of the plunger rod and the plunger rod cross section is not prevented from moving in a tilting direction by the minimum product container cross section, and a plunger rod centering aid a distal end of the plunger rod limits the movement of the plunger rod in the tilting direction.

An auto-injector includes a chassis and a carrier subassembly. The carrier subassembly includes a carrier arranged inside a case, a drive spring, a plunger comprising a ramp member, the plunger configured to be pushed in a proximal direction by the drive spring, and a ramp attached to the carrier, wherein the ramp member on the plunger in an initial state is locked to the ramp on the carrier to form a ramped engagement to the carrier, the plunger prevented from rotating out of the ramped engagement depending on a relative longitudinal position of the carrier relative to the chassis, wherein the plunger is arranged to be released and to rotate out of the ramped engagement upon the carrier translating a pre-defined distance in a proximal direction relative to the chassis.

The present invention relates to a medicament delivery device comprising a housing, a biased medicament delivery member guard arranged movable in relation to the housing from a proximally extended position to a retracted position, a power pack comprising a plunger rod and a force element arranged to act on said plunger rod, which power pack is actuated by a release clip movable in relation to the housing and arranged to said plunger rod for releasably holding said plunger rod with the force element in a tensioned state; a rotator rotatably arranged inside said housing, which rotator is arranged with a guide element and a medicament delivery member guard lock element on its outer surface, wherein said medicament delivery member guard is arranged with release clip activation elements operably arranged to act on said release clip for releasing said plunger rod, and wherein said medicament delivery member guard is further arranged with a rotator activator element arranged to cooperate with said guide element for turning said rotator, upon movement of said medicament delivery member guard to the retracted position, and wherein, upon movement of said medicament delivery member guard back to the extended position, said rotator activator element will engage said medicament delivery member guard lock element and lock said medicament delivery member guard in a shielding position after removal of said medicament delivery device from a medicament delivery site.

A drive mechanism for a delivery device is presented containing, a rotator having an outer surface and an inner surface, the rotator configured to rotate from a first position to a second position. A needle cover having an inner surface that engages the outer surface of the rotator. A rotatable plunger rod having an outer surface configured to engage the inner surface of the rotator. When the rotator rotates from the first position to the second position, the rotatable plunger rod is rotated by the rotator and a plunger rod spring is released from a pre-tensioned state to exert a force on the rotatable plunger rod.