A medicine injector in which a barrel with a receiving cavity is adapted to slidably receive a syringe subassembly for axial movement therein. Upon removal of a safety and release of a syringe driver, the syringe driver moves forward and injects the syringe needle. Penetration controls are shown for controlling needle penetration depth. In one form the penetration control uses a sleeve and spring which are radially adjacent. A cushioning ring or other cushion may be used to reduce syringe breakage. A load distribution and guide ring may be used to distribute loading applied to the syringe and help guide the moving syringe.

A medicament injection device comprising: a main body; a medicament cartridge holder fixed with respect to the main body, wherein the medicament cartridge holder is configured to hold a medicament cartridge; a needle carrier carrying a needle, wherein the needle carrier is axially movable with respect to the main body; and a rotatable cap at a distal end of the device, wherein the cap comprises a first pre-stressed spring coupled to the needle carrier, wherein the cap is arranged so that rotational movement thereof causes release of the first pre-stressed spring thereby causing the needle carrier to move axially towards a proximal end of the device.

An injection apparatus includes a hollow body having a first end at which a hollow needle is or can be located. A bung with a rupture seal membrane is located within the hollow body. A piston is also located within the hollow body. The piston, the hollow body and the bung define a volume containing a liquid medicament. The bung is nearer than the piston to the first end of the hollow body. The rupture seal membrane initially isolates the needle from the medicament. The rupture seal membrane is configured to rupture through fluid pressure alone without the rupture seal membrane contacting the needle, thereby allowing the medicament to be expelled through the needle upon movement of the piston causing the provision of pressure to the medicament.

This invention is designed and intended to provide simple, precise delivery of a variety of medications to mucosal surfaces of a living subject, human or non-human animal, including but not limited to the nasal or rectal mucosa, which sites afford rapid absorption and therefore onset of effect of the thus delivered medication. Such medications include, but are not limited to, anticonvulsants, drugs to treat anaphylactic shock, antidotes for poisoning, and medications which are required urgently where either a parenteral formulation is not available or an i.v. route is difficult. Simplicity and needle free safety of use of the various embodiments of the invention allows its operation by laypersons, school-teachers, nurses, paramedics and nonmedical persons in e.g. the armed service. Modular embodiments of the invention facilitate mixing and matching of delivery systems with different dosages and types of medications.

Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.

An injector device comprises a housing having a distal end and a proximal end; a medicament reservoir; a stopper for expelling a medicament out of the medicament reservoir; a cavity having an expandable volume which is arranged to move the reservoir or the stopper in a distal direction when the cavity is at least partially inflated with a fluid; and a fluid reservoir which is configured to dispense the fluid in to the cavity; wherein the cavity comprises a flexible tube, and the fluid reservoir is configured to dispense the fluid into the flexible tube.

The present invention relates to a mounting aid (400) for attaching a supplementary device (2) to an injection device (1), wherein the injection device (1) has an elongated housing (10) extending in an axial direction (3, 4), the mounting aid (400) comprises: a body (401) extending in axial direction (3, 4), configured to receive at least a portion of the housing (10) and having at least one radially extending engaging member (406, 416) to engage with a correspondingly shaped engaging member (456) of the housing (10) when in a specific position (M) relative to the housing (10), and wherein the body (401) comprises a side wall (402) with an abutment face (410) facing in a proximal direction (4), wherein the abutment face (410) is defined on a plane that is inclined to the axial direction (3, 4).

A medical cartridge containing multiple doses of a medical drug is disclosed. An outlet end is arranged to be connected to an injection needle for delivering the medical drug. The medical cartridge comprises a one way valve arranged in an interior part of the medical cartridge at a position near the outlet end. The one way valve allows a fluid flow from the interior of the medical cartridge towards the outlet end, but prevents a fluid flow from the outlet end towards the interior of the medical cartridge. Thereby the risk of contamination of the medical drug remaining in the cartridge is minimized.

A reloadable medicine injector and methods are described in which a barrel with a receiving cavity is adapted to slidably receive a syringe subassembly for axial movement therein. Upon removal of a safety and release of a syringe driver, the syringe driver moves forward and injects the syringe needle. A plurality of penetration controls are shown for controlling injection needle penetration depth. The penetration controls have an abutment and various lengths to provide different needle penetration depth positions. In one form of penetration control a sleeve is used against which the syringe or related parts contact. In another form the front return spring is used as a penetration control. A cushioning ring may be used to reduce syringe breakage. A load distribution and guide ring may be used to distribute loading applied to the syringe and help guide the moving syringe.

A valved container assembly (10) comprising a container (12) for containing a fluid, the container (12) extending in an axial direction and having at least one venting opening (12a) at a front end and at least one dispensing opening (12b). The valved container assembly (10) further comprising a valve (14) disposed in the container (12) and a plunger element (20) disposed axially rearward of the valve (14), the plunger element (20) being axially moveable in the container (12) and defining a first volume (22) in the container (12) between the plunger element (20) and the valve (14), where the plunger element (20) is configured to increase the pressure of a fluid in the first volume (22) upon axial movement relative to the valve (14). The valve (14) comprises a permanent seal (16) forming a fluidic seal between the at least one venting opening (12a) and the first volume (22), and a resilient seal (18) that is axially rearward of said permanent seal (16) and is moveable between a sealing configuration and an open configuration. In the sealing configuration the resilient seal (18) forms a fluidic seal with the container (12) between the at least one dispensing opening (12b) and the first volume (22). In at least one axial position of the valve (14) in the container (12) when the resilient seal (18) is in the open configuration the first volume (22) is fluidly connected to the at least one dispensing opening (12b). The resilient seal (18) is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume (22) exceeding a predetermined pressure threshold.