A method and assembly are disclosed for interfacing between a drug cartridge and a drug delivery device. Optionally, the drug delivery device includes a compartment that retains the cartridge during drug delivery and/or a stopper pushing assembly mounted to the device behind (proximal to) the compartment. In some embodiments, the cartridge may be inserted laterally into the compartment in front of the pushing assembly. For example, the delivery device may include a moving cartridge bay. The cartridge is optionally inserted into the bay and/or the bay and cartridge optionally move into the cartridge compartment. Alternatively or additionally, the cartridge compartment may have a proximal opening into which the cartridge is inserted and/or the pushing assembly may be moved into position after insertion of the cartridge. In some embodiments the cartridge may have a distal seal that is broken by a longitudinal movement.

A medicament packaging assembly for installation in a medicament delivery device is disclosed. The packaging assembly comprises a cartridge having a medicament chamber, a sealing element for sealing a distal end of the medicament chamber, a sealing element release member, a cannula and a removable cap member. The assembly is switchable from a starting configuration in which the release member is spaced from the sealing element to an activated configuration in which the release member cooperates with the sealing element to connect the medicament chamber to the cannula. The packaging assembly further comprises a first chamber defined in part by the cap member and arranged for receiving the cannula such that at least a distal end of the cannula is sealed in the first chamber when the cap member is in place, and a second chamber defined in part by the sealing element and arranged for receiving the release member such that at least a proximal end of the release member is sealed in the second chamber when the assembly is in the starting configuration. The assembly can be pre-assembled in the starting configuration for subsequent installation in the device.

The present disclosure relates to a medicament delivery device including a cartridge holder to which an injection needle holder can be fixed, the injection needle holder holding an injection needle having a proximal end and a distal end, the proximal end being protected by an inner injection needle cap detachably connected to the injection needle holder, the cartridge holder being mounted in a housing and configured to receive a cartridge of medicament, a cap assembly detachably connected to the housing, and a gripping mechanism configured to remove the inner injection needle cap from the injection needle holder when the cap assembly is pulled away from the cartridge holder.

A delivery assembly includes a console including a vial containment region and a vial engagement mechanism extending from the console within the vial containment region. The engagement mechanism is configured to engage a vial assembly. The delivery assembly further includes a sled assembly removably coupled to the console at the vial containment region and a safety shield removably coupled to the console over the vial containment region such that the vial engagement mechanism and the sled assembly are encapsulated within the safety shield when the safety shield is coupled thereto. The sled assembly, the vial assembly, and the safety shield are configured to inhibit radioactive emissions from within the vial containment region.

A triggering mechanism for a medicament delivery device, wherein the triggering mechanism comprises: a delivery member cover, a rotator, and a delivery member hub, wherein the delivery member cover is configured to move linearly relative to the rotator, wherein the delivery member cover is configured to cause rotation of the rotator when the delivery member cover is moved linearly in a first direction, and wherein the rotator is configured to cause linear movement of the delivery member hub in a second direction opposite to the first direction when the rotator is rotated.

An auto-injector may include a container capable of comprising a medicament; a shuttle coupled to the container and on a horizontal path with a first state and a second state; an energy source configured to release energy to translate the container and to translate the shuttle, preferably the energy source is pressurized fluid from a can; an impediment preventing horizontal movement of the shuttle before activation of the auto-injector; and a needle having a first end configured to extend out of the auto-injector, and a second end configured to extend into the container, wherein the second end of the needle and the container are not in fluid communication with one another before activation of the auto-injector.

Device for dispensing a fluid product comprising a body (1) having a dispensing opening (12) and a piercing element (4), said body (1) containing a reservoir (10) containing at least two doses of fluid product, said reservoir (10) having a proximal axial opening closed by a membrane (30) and a distal axial opening closed by a piston (20), mounted in a sliding manner in said reservoir (10) in order to dispense a dose of fluid product on each actuation, said reservoir (10) being axially movable with respect to said body (1) between a rest position, in which said piercing element (4) does not pass through said membrane (30), and a dispensing position, in which said piercing element (4) passes through said membrane (30), said membrane (30) being capable of reclosing in a sealed manner after each actuation, when said piercing element (4) comes back out from said reservoir (10), said device comprising a lateral actuation system having an actuating member (50), laterally movable with respect to said body (1) between a rest position and an actuating position, said actuating member (50) being resiliently biased towards the rest position thereof, said actuating member (50) comprising a first cam (51) cooperating with said reservoir (10) and a second cam (52) cooperating with said piston (20), such that the movement of said actuating member (50) to the actuating position thereof first moves said reservoir (10) to the dispensing position thereof then causes said piston (20) to slide in said reservoir (10), to dispense a dose of fluid product.

An injector device for delivering a liquid medicament comprises an injector body having a proximal end and a distal end. The injector device further includes a syringe slidably received in the injector body and moveable from a first position to a second position towards the distal end of the body. Additionally, the injector device comprises a needle holder between the syringe and the distal end of the body, and a needle held in the needle holder. The needle has a distal end extending toward an opening in the distal end of the body, and a proximal end extending toward the syringe. The injector device also comprises a syringe biasing member within the body configured to bias the syringe into the second position. The syringe is spaced from the needle in the first position and is in engagement with the proximal end of the needle in the second position.

A drug self-delivery device comprising a body portion containing a drug vial and a needle assembly, where the body portion is slidably engaged to a trigger portion. When engaged by a user pressing the trigger portion against the user's flesh, the needle assembly relative to the drug vial so as to align a needle port with an integral drug delivery port connected to the drug vial thereby allowing fluid flow of medication through the needle. Seals engaged by a penetration spring prevent loss of medication and prevent the need for direct connection between the needle assembly and the drug vial.

A medicament injection device is disclosed comprising a housing containing a medicament cartridge holder; a rotatable cap assembly; a needle holder holding a needle, the needle holder being releasably supported by the cap assembly, a pre-stressed spring coupled to the medicament cartridge holder; wherein the cap assembly is arranged so that rotation thereof releases the pre-stressed spring, causing the medicament cartridge holder to move axially in a distal direction towards the needle. A method of operating the device is also disclosed.