A problem with injecting cells such as fat cells into organic tissue to act as a filler material is that the cells must be distributed evenly and reasonably thinly to ensure that all of the injected cells are situated near to a blood supply and do not die. Injecting devices have been produced that use electronic controls and electro-mechanical mechanisms to improve distribution. The present approach however solves the problem of even distribution by coupling a skin surface sensing means to a plunger in a reservoir of the filler cells. In this way, the flow of cells out of a cannula relates directly to the rate at which the tip of the cannula penetrates the organic tissue into which the cells are being injected.

A device for controlling delivery of a fluid to a patient is disclosed having an injector device having a cylindrical body and a plunger having a head having a valve, the valve capable of opening and closing, the plunger for insertion into the cylindrical body of the injector device. A device for controlling delivery of a fluid to a patient is also disclosed having an inlet end, an outlet end, a side having a portion of elastic material, the elastic material capable of expanding or contracting with the device for insertion between an injector device and a manifold or an injector device and a catheter.

Fill-finish assemblies facilitating the manufacture of a drug delivery device are disclosed. The fill-finish assembly may include a container, an insertion mechanism, a fluid pathway connection assembly disposed between the container and the insertion mechanism, and a carrier. The insertion mechanism may include a delivery member and an insertion mechanism housing. The insertion mechanism may be configured to move the delivery member from a retracted position inside the insertion mechanism housing to a deployed position outside the insertion mechanism housing. The fluid pathway connection assembly may be selectively activatable to establish fluid communication between the container and the delivery member. The carrier may have a hollow interior containing at least a portion of each of the container, the insertion mechanism, and the fluid pathway connection assembly. The carrier may be configured to hold the container, the insertion mechanism, and the fluid pathway connection assembly in alignment with each other.

A device for controlling delivery of a fluid to a patient is disclosed having an injector device having a cylindrical body and a plunger having a head having a valve, the valve capable of opening and closing, the plunger for insertion into the cylindrical body of the injector device. A device for controlling delivery of a fluid to a patient is also disclosed having an inlet end, an outlet end, a side having a portion of elastic material, the elastic material capable of expanding or contracting with the device for insertion between an injector device and a manifold or an injector device and a catheter.

A needle assembly for medical or surgical use is disclosed, such as for hemodialysis. A representative needle assembly comprises an outer needle assembly and an integral needle tip protector. A representative outer needle assembly comprises: an outer needle comprising: a first lumen; a first aperture with a sharp needle tip at a first distal end of the outer needle; and a second aperture arranged opposite the first aperture. In another embodiment, the outer needle has a longitudinal slot and the integral needle tip protector includes a sliding connector which is slidable in the longitudinal slot. The integral needle tip protector is arranged within the first lumen and moveable between a retracted configuration and an extended configuration, and comprises: a needle tip cover arranged to shield the sharp needle tip in the extended configuration, the needle tip cover having a smooth or beveled distal surface forming a blunt tip.

The application discloses a multi-chamber, multi-formulation fluid delivery system, comprising a multi-chamber applicator in fluid communication with multi-chamber packaging. Applicators according to the instant disclosure have reduced squeeze-strength requirements, and are useful for dispensing fluids, including medicaments, to animals, including livestock animals. The multi-chamber packaging provides separate storage for formulations containing incompatible active ingredients, and is suitable for use with the multi-chamber applicator. The application also discloses methods for using the system to simultaneously deliver multiple active ingredients, at least some of which are not suitable for co-formulation, thus reducing the time, economic burden and animal stress involved with applying multiple, separate formulations to animals.

A syringe assembly for a drug delivery device. The syringe assembly includes a syringe barrel having a proximal end, a distal end, and a longitudinal axis. A needle assembly is operatively coupled to the syringe barrel and includes a needle hub and a needle attached to the needle hub. A flexible connection is disposed between the syringe barrel and the needle hub and forms a fluid pathway between the syringe barrel and the needle. The flexible connection enables the needle assembly to be moveable from a filling position, in which a longitudinal axis of the needle assembly is parallel to a longitudinal axis of the syringe barrel, to an assembled position, in which the longitudinal axis of the needle assembly is not parallel to the longitudinal axis of the syringe barrel.

An injector includes an injection needle and an activation button assembly operatively connected to the injection needle. The activation button assembly is translatable from an unactuated position to an actuated position, the actuated position being visually different than the unactuated position. A position of the activation button assembly between the unactuated position thereof and the actuated position thereof defines a threshold point, and movement of the activation button assembly beyond the threshold point secures the activation button assembly in the actuated position, and drives the injection needle from a retracted position thereof to an injection position thereof.

A drug delivery device comprises a medication container containing medication for delivery and a detachable unit having an electronic circuit with a microprocessor. The electronic circuit is open and non-operational when the detachable component is assembled on the drug delivery device; and the electronic circuit is closed and operational when the detachable component is detached from the drug delivery device. The detachment of the detachable unit is an essential step to operate the drug delivery device. The detachable unit can be an activation protection cap or a needle shield remover for an autoinjector device. Alternatively, the detachable unit can be a needle shield remover for a pre-filled syringe.

An automatic injection device has an insertion needle configured to be inserted into a patient and a drug container which contains a pharmaceutical product and includes a plunger. The automatic injection device also has a fluid path which fluidly connects the drug container to the insertion needle, and a drive system configured to cause linear movement of the plunger to force the pharmaceutical product into the fluid path. The passive drive system has a movable element. The movable element has a shape memory alloy and is configured to change shape to move the plunger.