The present disclosure provides aseptic vial piercing and sterilization systems, and methods of assembling, using and sterilizing same. The systems and methods utilize a pre-sterilized primary container including a first end, a first cavity, a second end with an opening in communication with the first cavity, a septum at least partially sealing the opening, and a product within the first cavity. The systems and methods include an injection assembly including a first end portion of a hollow flowpath forming member. The injection assembly and the primary container may be assembled in a non-sterile environment to form a second cavity extending about the first end portion of the flowpath forming member and to the primary container. The second cavity may then be selectively sterilized in a non-deleterious manner to the product to allow the first end portion to aseptically pierce the septum to extend into the first cavity.

A fluid dispenser device having a reservoir (10) containing fluid; a dispenser head (20) provided with a dispenser orifice (21); and a piston (45; 70) for dispensing at least a portion of the fluid through the dispenser orifice (21). The reservoir (10) is closed in leaktight manner by a closure element (25) before actuation. The device includes a passage (40) for connecting the reservoir (10) to the dispenser orifice (21) during actuation, the passage (40) including a hollow sleeve (41) that is stationary relative to the dispenser head (20), for sliding around the closure element (25) during actuation, so as to open the passage (40).

A cartridge includes a first opening, a second opening, a channel, an intraocular lens arranged in the channel, and a cartridge plunger arranged in the channel and configured to firstly preload the intraocular lens by moving the cartridge plunger towards the first opening, then to fold the lens by moving it in the tapered region, and finally to push the lens out of the channel via the first opening. The cartridge is configured to be coupled to a syringe such that a fluid can be injected into the channel, and as a result the cartridge plunger can be propelled in a movement direction towards the first opening. The cartridge plunger includes a first cartridge plunger longitudinal end, a second cartridge plunger longitudinal end, and a fluid line via which the fluid can be injected from the second to the first cartridge plunger longitudinal end and finally to the intraocular lens.

The present disclosure relates to a medicament container for accommodating a liquid medicament. The medicament container includes an elongated container barrel defining a longitudinal direction and having a proximal end and a distal end. The proximal end is opposite the distal end. The container barrel includes a proximal container cross section at the proximal end. The elongated container barrel includes a distal container cross section at the distal end and the proximal container cross section is substantially identical to the distal container cross section. The medicament container further includes a seal arranged at the distal end and extending across the distal container cross section, and a retainer engaged with the seal and engaged with the elongated container barrel to fix the seal to the distal end.

Disclosed here are syringe assemblies that include a modified syringe tip to penetrate a subject to obtain or administer a substance. The syringe system consists of a syringe body with or without a modified syringe tip with a standard or modified plunger. The modified syringe tip or modified plunger protrusion can penetrate a subject, such as the skin of a patient or a membrane on sealing a container containing medicine, or a seal of an empty vial.

The present invention relates to a drug injection cartridge and a drug injector comprising same, and has an anti-pushing part (100) formed between a needle part (10) and a cartridge (20), thereby preventing a rubber film from being expanded by pressure applied to the cartridge (20), such that a drug does not leak, and the accuracy of drug injection can be improved.

The present disclosure provides aseptic vial piercing and sterilization systems, and methods of assembling, using and sterilizing same. The systems and methods utilize a pre-sterilized primary container including a first end, a first cavity, a second end with an opening in communication with the first cavity, a septum at least partially sealing the opening, and a product within the first cavity. The systems and methods include an injection assembly including a first end portion of a hollow flowpath forming member. The injection assembly and the primary container may be assembled in a non-sterile environment to form a second cavity extending about the first end portion of the flowpath forming member and to the primary container. The second cavity may then be selectively sterilized in a non-deleterious manner to the product to allow the first end portion to aseptically pierce the septum to extend into the first cavity.

A syringe assembly includes a barrel defining a chamber therein, pressurized sterile air in the chamber, a plunger including a piston slidable in the chamber in a sealing relation to displace a fluid in the chamber, a seal configured to retain the pressurized sterile fluid in the chamber between the piston of the plunger and the seal when the plunger is stationary, and a needle assembly extending distally from the barrel and in fluid communication with the chamber of the barrel.

The present invention relates to a mixing and injector device which can include: a housing having a plurality of separate and distinct chambers disposed therein; one or more displacement mechanisms corresponding to each of the plurality of chambers disposed within the housing; a needle assembly being provided about one of the plurality of chambers, the needle assembly including the following: a septum; a needle being separated from the plurality of chambers by the septum, the needle having a proximal end configured to pierce the septum in an actuated state; and a needle carrier, the needle carrier being configured to translate axially with respect to and toward the septum and pierce the septum and provide fluid communication from the plurality of chambers through the needle in the actuated state.

A needle and pre-filled syringe system that provides ultra-low dosage waste and automatic needlestick protection. A syringe assembly is pre-filled with an injection material. A needle head assembly attaches to the syringe assembly. A spacer is disposed between the needle head assembly and the syringe assembly. The spacer has a central opening. The needle head assembly supports a needle with a needle base. When assembled, the needle base passed into the central opening of the spacer. The needle head assembly also contains a safety slide that can selectively cover the needle. During an injection, pressure and/or contact with the plunger head causes the spacer to contact and move the safety slide. The safety slide moves to cover the needle during the injection procedure, therein rendering the needle safe before the injection process is even complete.