When at least a part of a shaft portion of a plunger is stored in a proximal end side storage portion of a storage tray, the proximal end side storage portion supports a syringe body and the plunger in a state in which the syringe body and the plunger cannot approach each other since a first contact portion comes into contact with a proximal end surface of a body flange and a second contact portion comes into contact with a distal end surface of a pressing operation portion, and the part of the shaft portion of the plunger is prevented from separating since protruding pieces come into contact with the part of the shaft portion of the plunger.

A drug delivery device (10) includes a housing (26), a syringe assembly (16) including a barrel (52), a stopper (54), a cannula (56), and a rigid needle shield (58) receiving at least a portion of the cannula, with at least a portion of the syringe assembly positioned within the housing, a drive assembly (40), with at least a portion of the drive assembly positioned within the housing, a cap (18) secured to the housing, with the cap including an outer portion (20) defining an interior space and a retainer (160) comprising a body with a removal projection (164) configured to remove the rigid needle shield upon axial movement of the outer portion of the cap away from the housing, and a needle cover (22) having a pre-use position, an actuation position, and a post-use position. The outer portion receives a portion of the needle cover, with the outer portion configured to prevent movement of the needle cover from the pre-use position to the actuation position.

A drug delivery device includes a housing, a syringe assembly including a barrel, a stopper, and a cannula, with at least a portion of the syringe assembly positioned within the housing, a drive assembly configured to move the stopper within the barrel upon actuation of the drive assembly, with at least a portion of the drive assembly positioned within the housing, a needle cover having a pre-use position where the cannula is positioned within the needle cover, an actuation position where the needle cover is configured to actuate the drive assembly, and a post-use position where the cannula is positioned within the needle cover, and a cap receiving a portion of the needle cover, with the cap configured to prevent movement of the needle cover from the pre-use position to the actuation position.

A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O.sub.2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.

An injector comprises a cylindrical barrel including a discharge port, a seal body coming into close contact with an inner circumferential surface of the barrel, a plunger for pushing and moving the seal body to the discharge port side of the barrel, and a stopper disposed on one of the barrel and the plunger and coming into elastic contact with the other in a radial direction of the barrel.

A female syringe of a syringe kit includes a female syringe barrel including a cylindrical portion into which a nozzle of a male syringe is insertable, a hollow cylindrical packing arranged in the cylindrical portion, and a cap detachably attached to the cylindrical portion. When the cap is detached from the cylindrical portion, the packing remains in the cylindrical portion, a distal end opening is opened, and the nozzle of the male syringe is fitted in a liquid-tight manner to an inner side of the packing.

The present disclosure relates to an applicator device for depositing a lubricant onto an inside surface of a barrel of a medicament container. The applicator device includes a sprayer defining a longitudinal direction and sized for insertion into an interior of the barrel along the longitudinal direction. The sprayer is operable to eject the lubricant. A centering element is connected to the sprayer and operably engageable with the barrel in a predefined position or orientation to align the sprayer relative to the barrel.

The invention generally relates to prefilled disposable medication devices, method of making, and using to store, contain and deliver at least a diluent for allergenic extract and more particularly to a prefilled cartridge containing a diluent for allergenic extract for use with an injection pen for allergy treatments.

A primary drug container is described having an injection-molded thermoplastic wall having an internal surface defining a lumen, a PECVD (plasma-enhanced chemical vapor deposition) drug-contact coating, and a polypeptide composition contained in the lumen. The drug-contact coating is on or adjacent to the internal surface, positioned to contact a fluid in the lumen, and consists essentially of SiOxCyHz. The primary drug container contains between a lower limit of 1,000 and an upper limit of 100,000 particles having effective spherical diameters greater than 2 and no more than 10 micrometers (μm) per mL of solution.

A method of inserting a lubricant free stopper into a lubricant free syringe barrel or lubricant free cartridge tube is disclosed. The method includes (1) inserting a stopper with a sealing rib into a placement region, (2) lowering the body of the insertion tube into a syringe barrel or cartridge tube to a position located past the barrel flange or top of the cartridge tube, (3) maneuvering the stopper to a distal opening of the insertion tube using an insertion pin, (4) retracting the insertion tube while the stopper remains in a fixed position within the syringe barrel or cartridge tube, and (5) fully retracting the insertion pin and the insertion tube from the syringe barrel or cartridge tube. The method is lubricant free or substantially lubricant free. The insertion tube may be electropolished and/or extrude honed.