The present invention relates to a valve system for an inflatable portion of an indwelling medical device and more particularly to a valve system for fluid regulation of a catheter comprising a fluid inflatable portion that undergoes pressure changes within the body during use.

A drug delivery device includes a reservoir for containing a medical product, a distally projecting end-piece having an outer surface and a total length measured along a longitudinal axis of said end-piece, said end-piece defining an axial passageway for the transfer of said medical product contained in said reservoir, wherein a gripping surface is provided on a portion of said outer surface, said portion being located in a distal region of said end-piece, the length of said portion representing at most 40%, preferably less than 33%, of the total length of the end-piece. An assembly includes such a drug delivery device and an adaptor intended to be mounted onto the end-piece.

The dual syringe with percutaneous cannula is a medical device for harvesting and transferring cells for autologous transplantation without the requirement of a surgical setting or ambulatory care. The dual syringe is a closed sterile system that allows for the harvesting syringe to harvest the cells/tissue from a first location of a patient which is then centrifuged to aggregate the cells. The aggregated cell pellet is transferred to a transfer syringe. The cell pellet is then reinjected by the transfer syringe into the patient at a second location for therapeutic purpose. The percutaneous cannula permits insertion of a cannula, with the assistance of a needle, without the need of a surgical incision or trocar.

An adapter for use with an injection device includes a first end, a second end and a first longitudinal axis extending from the first end and the second end. The adapter also includes a chamber defined by a sidewall between the first end and second end and a nozzle having a passageway extending through the sidewall, the passageway having an input at the chamber, an output at an outer surface of the body and a passageway axis extending from the input to the output, the passageway axis being angularly offset from the longitudinal axis of the channel. A cartridge can include such an adapter.

Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit comprises a cassette unit housing defining a cassette unit housing cavity and a needle projection aperture. The housing cavity may receive a syringe. Axially movable within the barrel of the syringe for forward movement into contact with the syringe plunger, there is a plunger slaving part defining a circumferential wall arranged for frictional sliding relationship with the inner wall of the barrel, a rear drive-receiving face and a front plunger-contacting face. The plunger slaving part is arranged such that when a drive load is applied to its rear drive-receiving face to bring the front plunger-contacting face into contact with the plunger the drive load is evenly transmitted. The circumferential wall is provided with slide restrictors that restrict frictional sliding movement thereof in relation to the inner wall of the barrel.

The dispensing device includes a hollow tube having an open upper end and an open lower end, as well as a horizontal bar disposed between the walls of the hollow tube adjacent to the open lower end. A disc is movably positioned within the hollow tube, the disc having a central aperture defined therein. A string or other flexible member has one end secured to the disc. The other end of the string is drawn downward in the tube, looped around the horizontal bar, then drawn upward through the central aperture in the disc and out the open upper end of the tube. A semi-solid medication is loaded in the tube between the disc and the open lower end of the tube. When the string is pulled out of the upper end of the tube, the disc is drawn downward, dispensing the medication.

Apparatus and methods of assembling apparatus (e.g. a pre-filled syringe). The methods comprising setting a length of a plunger rod of a plunger rod assembly, and fitting the plunger rod assembly to a barrel of the syringe, the barrel having an opening at a forward end thereof and comprising a bung positioned therein and creating a volume between the bung and the opening, the volume at least partially filled with a substance for delivery from the syringe. Setting the length of the plunger rod assembly may comprise at least partially inserting the plunger rod into the barrel such that a forward end of the plunger rod contacts the bung, wherein, after assembly, the length of the plunger rod defines a separation between the bung and the forward end of the plunger rod.

A syringe is provided, including a syringe barrel, a needle set and a push rod. A front end part is provided in the syringe barrel. An end of the needle set has an open area, the open area is transversely provided with a first snap part. The push rod is slidably disposed within the syringe barrel, and an end of the push rod facing the front end part has a second snap part. When the push rod is slidingly moved to the front end part, the second snap part is engaged with the first snap part.

A safety syringe comprising a barrel having an opening at an end thereof and a bung positioned in the barrel and creating a volume between the opening and the bung. The safety syringe also comprises a handle portion secured to the barrel and a syringe plunger slidably engaged with the handle portion and moveable within the barrel on an inward stroke to drive the bung forwards within the barrel to cause a substance within the volume to be expelled from the opening. The safety syringe further comprises a rotation mechanism configured to rotate the syringe plunger within the barrel at a point during the inward stroke when the syringe plunger is in contact with the bung, such that a rotational force is applied to the barrel and a brake connected to the handle portion and configured to provide a frictional force to resist the rotational force applied to the barrel.

A prefilled syringe includes a tubular containment body extending along an axis between a front end element and a rear end element, a fixed plug and two sliding plugs. A bypass channel in the initial position of the syringe is between the first two plugs which form, together with a third plug at the end of the syringe plunger, a first containment chamber containing a first liquid substance and a second containment chamber containing a second solid or liquid substance. The fixed plug is in contact with the front end element and is provided with a non-through cavity offset with respect to the axis and facing towards the front end element.