The present disclosure relates to a drug delivery device, comprising a housing adapted to receive a medicament container, a plunger and a plunger release mechanism, the plunger release mechanism comprising a first plunger boss arranged on the plunger, a profiled slot arranged on the housing and adapted to be engaged by the first plunger boss so as to inhibit movement of the plunger in a distal direction, wherein the plunger is rotatable about a longitudinal axis to release the first plunger boss from the profiled slot so as to allow movement of the plunger in the distal direction, a sleeve coupled to the housing to permit movement of the sleeve relative to the housing, wherein a sleeve ramp is arranged on the sleeve, the sleeve ramp adapted to engage a rib or boss on the plunger to rotate the plunger to release the first plunger boss from the profiled slot when the sleeve is moved in a proximal direction.

A system having a monitoring device and a medicament delivery device is presented wherein the monitoring device is configured to be releasably attached to the medicament delivery device and to monitor an operation of the medicament delivery device. The monitoring device has a body defining a cavity for receiving the medicament delivery device; a biased holding unit arranged in the body and configured to retain the medicament delivery device to the body in a secure state; wherein the biased b holding unit is movable within the body between a first position in which the medicament delivery device is in an unsecure state and a second position in which the medicament delivery device is in the secure state. The biased holding unit can have an enclosing member having a engagement structure; and in that the biased holding unit there can be a locking element fixed to or integral with the enclosing member, wherein the engagement structure is configured to interact with an engaging member on the medicament delivery device and the locking element is configured to interact with a counter locking element arranged to the body when the biased holding unit is in the second position.

Devices and methods are disclosed for assisting a user of a drug delivery device with an application executing on a mobile computing device. The mobile computing device may receive information from the drug delivery device related to its condition and/or operation and subsequently select an informational and/or instructional prompt to be displayed to the user based on the received information. The mobile computing device may also generate a display in the application including the selected informational prompt and/or the instructional prompt. Accordingly, the user of the drug delivery device can be guided through the drug delivery process in real time, thereby reducing the likelihood of improper or incomplete use of the drug delivery device.

An automatic injection device with flow regulation. The automatic injection device has an insertion needle configured to be inserted into a patient and a drug container which contains a pharmaceutical product and includes a plunger. The automatic injection device also has a fluid path which fluidly connects the drug container to the patient via an insertion device, a potential energy source, and a regulator configured to restrict release of potential energy and restrict linear movement of the plunger and pharmaceutical product into the fluid path at a proscribed pace. The regulator includes a clock escapement mechanism and a wire and pulley system including a wire coupled to at least one pulley. The potential energy source may be a spring that surrounds the drug container and may be directly coupled to the plunger and the wire such that movement of the spring and the wire is restricted over time.

A medicament delivery device is presented having a front-end device with a front-end housing and a delivery member cover that moves along a longitudinal axis between an extended position and a retracted position relative to the front-end housing, and a medicament container holder arranged in the front-end housing that receives a medicament container; and a reusable base device that is detachably connected to the front-end device, the base device has a plunger, a motor to drive the plunger inside the front-end housing, and wherein the motor drives the plunger from a second end position back to an initial end position, and a motor switch having a first switch position that changes to a default switch position by displacement of the delivery member cover when the delivery member cover is moved back from a retracted position to an extended position causing the motor to rotate in a reverse direction and drive the plunger from the second end position to the initial end position.

An auto-injector includes a chassis and a carrier subassembly. The carrier subassembly includes a carrier arranged inside a case, a drive spring, a plunger comprising a ramp member, the plunger configured to be pushed in a proximal direction by the drive spring, and a ramp attached to the carrier, wherein the ramp member on the plunger in an initial state is locked to the ramp on the carrier to form a ramped engagement to the carrier, the plunger prevented from rotating out of the ramped engagement depending on a relative longitudinal position of the carrier relative to the chassis, wherein the plunger is arranged to be released and to rotate out of the ramped engagement upon the carrier translating a pre-defined distance in a proximal direction relative to the chassis.

A force actuated injection device including a body adapted to contain medication, a grip slidably disposed over the body, a lock disposed between the body and the grip, the lock when locked preventing movement of the grip relative to the body and when unlocked permitting movement of the grip relative to the body, a needle guard retractable relative to the body, a biasing member biasing the needle guard away from the body, and a resistance band disposed between the body and the needle guard adapted to resist initial needle guard retraction relative to the body, wherein force on the needle guard exceeding a predetermined amount overcomes a frictional force of the resistance band allowing the needle guard to retract relative to the body to unlock the grip relative to the body such that movement of the grip relative to the body causes medication to be delivered from the body.

A dosage verification system for use prior to administering an injection of a medicinal fluid drawn into a medical syringe, the system comprising a medical syringe having a barrel with an outwardly facing, flat indicia display surface, plunger having a plunger seal disposed inside and slidably engaging an inwardly facing wall of the barrel and a plunger handle projecting rearwardly from the barrel, and a hypodermic needle projecting forwardly from the barrel, all in combination with an imaging device configured to view and selectively capture, store or transmit a digital image of the plunger position relative to the barrel when a dose of the medicinal fluid is drawn into the fluid chamber of the barrel prior to an injection to verify and provide a record of the dosage drawn, and to alert a user prior to injection when an incorrect dosage is drawn into the fluid chamber of the syringe.

A drug solution administration device includes a drug solution reservoir, a drive unit, a rotation detection unit, and a control unit. The control unit counts the number of rotations of the drive unit from when a rotation sensor value reaches a blockage start threshold value until the rotation sensor value reaches a blockage detection threshold value. Further, the control unit determines that a blockage of a flow path has occurred when the rotation sensor value reaches the blockage detection threshold value, and rotates the drive unit in a direction opposite to a direction in which the drug solution is administered based on the counted number of rotations.

A device for administering a fluid can include a cylinder, a piston connected to a piston rod, and a tensioning device connected to the piston rod. The tensioning device includes a ramp which is rotatable via a motor, a ramp track, and a roller which is in contact with the ramp track and which is mounted rotatably in a driver. The driver can be connected to the piston rod via a joint. In a tensioning procedure, the ramp track is rotated such that the roller runs on the region of inclination as far as the second plateau and the piston is thereby moved to its rear end position. In a dispensing procedure, the ramp track is rotated until the roller runs over a transfer region and, on account of the tensioning, is accelerated toward the first plateau and, as a result, the piston is moved toward the an dispensing end.