The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

Methods, systems, and devices are disclosed for administering a medicament to a patient. In one aspect, a system includes an injection pen device in wireless communication with a mobile communication device. The injection pen device includes a housing including a chamber to encase a cartridge containing medicine, a dose setting and dispensing mechanism to set the mechanism to dispense a particular dose of the medicine from the loaded cartridge, a sensor unit to detect a dispensed dose based on positions and/or movements of the dose setting and dispensing mechanism, and an electronics unit in communication with the sensor unit to process the detected dispensed dose and time data associated with a dispensing event and to wirelessly transmit the dose data to a user's device. The mobile communication device provides a software application to provide the user with health information using the processed dose data.

The present invention provides a power unit (1) for a drug delivery device as well as methods for providing and mounting the power unit (1) in the drug delivery device. The power unit (1) comprises a first interface member (30) extending along a reference axis and comprising a hollow body (31) and a first engagement structure (35), a second interface member (10) comprising a tubular structure (11) extending at least partially through the hollow body (31) and having a skirt (12), and a second engagement structure (14) configured for releasable engagement with the first engagement structure (35), and a torsion spring (20) comprising a first end portion (23) being attached to the first interface member (30) and a second end portion (22) being attached to the second interface member (10), the torsion spring (20) being pre-strained to induce a relative rotational motion between the first interface member (30) and the second interface member (10). The first interface member (30) and the second interface member (10) are configured for relative motion along the reference axis from a first relative axial position in which the first engagement structure (35) and the second engagement structure (14) are engaged to prevent the relative rotational motion between the first interface member (30) and the second interface member (10) to a second relative axial position in which the first engagement structure (35) and the second engagement structure (14) are disengaged. In the first relative axial position of the first interface member (30) and the second interface member (10) the torsion spring (20) is accommodated in a user inaccessible space (39) defined by the hollow body (31) and the skirt (12).

An automated inspection system includes a sensor system that includes a sensor and is configured to generate a plurality of syringe scans by scanning each of a plurality of syringes. Each of the plurality of syringe scans is indicative of distance relative to the sensor. The automated inspection system also includes one or more processors configured to, for each of the plurality of syringes, analyze the respective syringe scan to determine (i) a first distance to a first portion (e.g., flange) of the syringe and (ii) a second distance to a second portion (e.g., plunger) of the syringe, and calculate a distance between the first and second portions based on the first distance and the second distance.

An actuation mechanism is presented for a medicament delivery device having a plunger rod arranged to act on a stopper of a medicament container, an actuator arranged slidable and connected to the plunger rod for acting on the stopper when said actuator is operated by displacing it in a longitudinal direction of the actuation mechanism, and an activator for activating the actuation mechanism and for setting a dose. The activator having a generally tubular activator sleeve provided with a spirally extending groove on an outer surface, the groove arranged with a length corresponding to the total amount of medicament to be delivered in a number of doses contained in said medicament container, where the groove is provided with an end wall, a stop ring arranged coaxial with said activator sleeve. The activator sleeve arranged with a follower positioned in the groove and the follower arranged to abut the end wall when the total amount has been delivered.

The invention relates to an injection device comprising an End-of-Content mechanism. The End-of-Content mechanism comprises a piston rod (10) being driven forward by a rotatable piston rod guide (20), a driver (50) attached to a dose setting tube (30) and an End-of-Content tube (40). The End-of-Content tube is moved axially forward during dose setting a distance which correlates to the size of the dose being set. When the accumulated set and ejected dose equals the injectable amount initially available in the cartridge (3), the End-of-Content tube engages a lock mechanism provided in the piston rod guide and the driver engages a stop surface on the End-of-Content tube. Once the End-of-Content mechanism is locked, no further dose can be set and the piston rod guide cannot be rotated. In order to provide a proper engagement between the piston rod guide and the driver, the End-of-Content mechanism is released during dose expelling.

A drug delivery device including a housing, a drug storage container, and a removable cap is provided. The removable cap may be configured to be removably coupled with the housing such that the removable cap has a storage position where the removable cap is coupled with the housing and at least partially covering an opening in the housing and a removed position where the removable cap is not coupled with the housing. The removable cap may include an outer portion, an inner portion, and a gap separating at least a portion of the inner portion and at least a portion of the outer portion such that the at least a portion of the outer portion is allowed to bend with respect to the at least a portion of the inner portion if the at least a portion of the outer portion is subjected to an external force. Additionally or alternatively, the removable cap may be configured such that an external force applied to the removable cap induces at least one bending moment in a proximal end and/or a distal end of the removable cap.

A cartridge-based computer controlled self-injection device automatically regulates time and dosage administered to a patient. Cartridges can be electronically tagged so the injection device can determine the content, volume, expiration date, and physician prescribed dosage timetable. Authentication verifies the device and ensures the proper patient is using the device with the appropriate therapeutic injectant. Authentication further provides information controlling device operation including expiration dates and clock synchronization. Therapeutic injectant administration statistics, such as date and time of administration of a therapeutic injectant are stored and provide to a health care provider for monitoring. Patients can be notified of nearing or missed administrations.

A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

A spring force assembly for biasing a displaceable stopper of a liquid medicament cartridge including a spring element arranged along a longitudinal axis, with brace elements and coupling elements, with the coupling elements restricting the distance between the brace elements which also restricts the possible expansion of the spring element.