Contemplated herein is a medication mixing device which can include a housing having therein a first chamber containing a first medicament component and a second chamber provided containing a second medicament component provided with a sealing structure selectively isolating the first chamber from the second chamber. The sealing structure can include a first sealing component having a first sealing interface and a second sealing component having a second sealing interface wherein a first compression force can be applied to the first and second sealing components causes the sealing interfaces to form a seal. The first compression force can then be configured to allow the first sealing component and the second sealing component to maintain at least one degree of freedom with respect to one another.

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.

An infusion apparatus including a body having an infusion reservoir and one end of the body adapted to receive a pierceable end of a vial, a barrel rotatably disposed in an opposing end of the body and having an internal fluid chamber, and a plunger received in one end of the barrel, wherein the barrel rotates relative to the body between a first position allowing bi-directional fluid flow between the barrel and the vial, and a second position allowing bi-directional fluid flow between the barrel and the infusion reservoir, and wherein the plunger is movable relative to the barrel to control the bi-directional fluid flow between the barrel and the vial and the bi-directional fluid flow between the barrel and the infusion reservoir.

An automatic mixing device, an actuating device having integrated plunger and configured to be removably mounted to the automatic mixing device, and a retractable syringe having the automatic mixing device are provided. The actuating device has an initially compressed spring and a trigger member that is rotatable to initiate spring decompression to drive depression of a mixing plunger seal of the automatic mixing device. Another seal located in an outer chamber of the mixing device is capable of axial movement upon depression of the mixing plunger, from a first position in sealing engagement with one or more apertures in an inner barrel to a second position intermediate the apertures and vents in an outer barrel. This allows depression of the mixing plunger to force a first substance from the outer chamber through the apertures to mix with a second substance in an inner chamber of the inner barrel. The mixed substance in the inner barrel is then delivered by the syringe with subsequent needle retraction.

A chemical liquid injector including a driving mechanism which applies a pressure to a chemical liquid in a container and pushes out the chemical liquid, and an injection control unit for setting operating conditions of the driving mechanism. The control unit has a main-injection condition determination section which determines injection conditions for a main injection, and an injection preliminary operation condition determination section which determines injection conditions for an injection preliminary operation, and is configured to execute the injection preliminary operation and the main injection consecutively in this order when injecting chemical liquid.

Low-profile fluid injection systems and methods for injecting fluid into a tumor within a body comprising an elongate member, a plurality of fluid delivery members, and a plurality of fluid reservoirs. Each of the plurality of fluid reservoirs may be fluidly coupled to a single of fluid delivery lumen of a single fluid delivery member such that each of the fluid delivery members is fluidly independent of every other fluid delivery member. The plurality of fluid delivery members may be configured to extend out of a distal end of the elongate member into the tumor when the system is positioned in the body of a patient. A fluid delivery mechanism may be operably coupled to the plurality of fluid reservoirs in order to deliver fluids from the plurality of fluid reservoirs to the plurality of fluid delivery members and inject the fluids into the tumor.

The present invention provides a delivery device for administration of active agent (12) containing compositions into the suprachoroidal space or supraciliary space. The invention provides methods of treatment of an ocular disease or condition accordingly. The invention also provides active agent containing compositions for delivery into the suprachoroidal space or supraciliary space.

A container adapter for a medical delivery device is disclosed. The medical delivery device has a container seat for holding a container, a dosage chamber, a dosing mechanism and a lock mechanism adapted to prevent operation of the dosing mechanism when no container is held in the container seat and to allow operation of the dosing mechanism when the container is held in the container seat. The container adapter includes an adapter container seat arranged to hold a container, a joint structure arranged to be detachably positioned in the container seat of the medical delivery device and to connect the adapter container seat to the dosing mechanism, and an unlock member adapted to activate the lock mechanism. A delivery assembly and a method of delivering a liquid to a patient from different containers is also disclosed.

A syringe-based device includes a housing, the housing including a port, and an actuator mechanism including a first member and a second member configured to be movably disposed within the housing. The first member includes a syringe body and a plunger movably disposed within the syringe body and including a first plunger seal. The second member includes a second plunger seal defining a channel and a valve fluidically coupled with the channel of the second plunger seal. The device also includes a first fluid reservoir and a second fluid reservoir. The device transitions from a first configuration to a second configuration in which a first type of fluid in the first fluid reservoir is delivered through a port, to a third configuration in which a second type of fluid within the second fluid reservoir is delivered through the port.

A fluid injection device having a body contacting an injection site (SI); fluid reservoirs (210); an injection needle (120) that injects the contents of the reservoir(s) (210); and a respective priming needle (125) associated with each reservoir (210) for penetrating into the reservoir (210) before dispensing the fluid. Each reservoir (210) includes a tube (145) connected at one end to a priming needle (125), and at the other end to the injection needle. The device includes a reservoir selector for selecting one or more reservoirs (210), the contents of which are dispensed during the next actuation. The selector has a rotary member (132, 135) with a cam (1320, 1350) to co-operate with the tubes (145) so as to open or close the flow of fluid through each tube (145).