Patent classifications
A61M15/0035
DRY POWDER COMPOSITIONS WITH MAGNESIUM STEARATE
A stable dry powder composition for inhalation includes acetylsalicylic acid in particles having a mass median aerodynamic diameter (MMAD) in a range of about 1 μm to about 5 μm. The dry powder composition may contain a pharmaceutically acceptable excipient, such as a stearate, in an amount ranging from about 0.04% (w/w) to about 0.06% (w/w), or from about 0.4% (w/w) to about 0.6% (w/w), of the composition.
Inhaler
An inhaler for inhalation of a formulation in powder form includes: a magazine which is rotatable and contains pre-dosed doses of the formulation in capsules, a housing which is substantially round or disc-shaped, the housing having a housing part in which the rotatable magazine is disposed, where the housing part is fixedly coupled to the rotatable magazine, and is removable from the housing in order to facilitate replacement of the magazine by inserting a new magazine.
Dose delivery device for inhalation
Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose.
METHODS FOR GENERATING AND DELIVERING DROPLETS TO THE PULMONARY SYSTEM USING A DROPLET DELIVERY DEVICE
A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 μm, so as to target the pulmonary system of the user.
Modular electronic inhaler
A modular electronic inhaler having an embedded system and a method for precise and repeatable delivery of multiple types of medications in different forms to the pulmonary system of a human user. The inhaler can include a first MDI housing defining an internal chamber for accommodating a MDI medication cartridge and a second DPI housing defining an internal chamber for accommodating a DPI medication cartridge. Meter reservoir compartments in each housing can automatically provide precise doses of medicine using vacuum pressure sensors. The sensors can be in communication with the internal embedded system/electronics (microcontroller) of the inhaler and the electronics/microcontroller can be in permanent communication with a software application running on the user's smart phone or other electronic device.
DEVICES AND METHODS FOR DELIVERING A SUBSTANCE TO A BODY CAVITY UTILIZING BLOW-FILL-SEAL TECHNOLOGY
A device is provided for delivering one or more substances within at least one body cavity. The device includes at least one pierceable vial comprising V.sub.sub [ml or mg] of the substances; the vial having at least one fluid discharging outlet port, configured for placement in proximity to the body cavity. The pierceable vial is configured to interface in a sealable manner with at least one pressurized fluid at volume V.sub.PF [ml] and pressure P.sub.PF [barg]. The device, upon actuation, permits the pressurized fluid to enter into the pierceable vial via the at least one fluid inlet port, entrains the substances, and delivers the substances through the fluid discharging outlet port to within the body cavity in the form of at least one selected from a group consisting of drops, droplets, stream, aerosol and any combination thereof.
Aerosol-generating system including a cartridge containing a gel
A cartridge for an aerosol-generating system may include a first chamber housing defining a first chamber and a second chamber housing defining a second chamber that is separate from the first chamber. The first chamber may contain an aerosol-forming substrate in the form of a gel, and the second chamber may contain a source of a desired compound. The first and second chamber housings may be separate or separable structures.
SPRAYER AND STORAGE DEVICE
A nebulizer and a storage device are provided. The nebulizer includes a casing, an atomization module fixed to the casing, a rotating module rotatably assembled to the casing, a linking module assembled to the rotating module, and a locking module. The linking module is configured to be connected to a bottom of the container bottle, and the starting module is configured to drive the nebulizer by being pushed, thereby enabling liquid in the container bottle to be atomized toward an outside of the nebulizer through the atomization module in an atomization process. The locking module is configured to be connected to a bottom of the container bottle. When the nebulizer completes a predetermined number of times of the atomization process, the locking mechanism is moved toward the casing and is then limited to restrict an operation of the nebulizer. Accordingly, after the nebulizer completes the predetermined number of times of the atomization process, the locking module can restrict rotation of the rotating module for preventing the nebulizer from using the container bottle arranged therein.
DRY POWDER INHALER WITH AN ADHERENCE MONITOR
A dry powder inhaler which contains a blister pack, such as a blister strip, is provided. The blister pack has a plurality of blisters, and a blister, or group of blisters, provides a dose of powdered medicament for inhalation. The blister pack has non-numerical indicia which encode an individual, unique number that is associated with each dose. The inhaler is adapted for mounting a monitor. The monitor comprises one or more sensors, such as optical sensors, for reading the non-numerical indicia on the blister pack.
AEROSOL PRESSURIZED INHALATION DELIVERY DEVICE AND METHODS FOR MANUFACTURE AND USE OF THE SAME
The present invention improves and enhances the delivery of one of an aerosolized or micellized formula by use of an aerosol pressurized inhalation delivery device. The device may include one or more replaceable or reusable components, including but not limited to a canister and a battery. Methods for using the device to deliver a controlled dosage via the delivery device are also described herein.