A personal vapor inhaling unit is disclosed. An electronic flameless vapor inhaler unit that may simulate a cigarette has a cavity that receives a cartridge in the distal end of the inhaler unit. The cartridge brings a substance to be vaporized in contact with a wick. When the unit is activated, and the user provides suction, the substance to be vaporized is drawn out of the cartridge, through the wick, and is atomized by the wick into a cavity containing a heating element. The heating element vaporizes the atomized substance. The vapors then continue to be pulled by the user through a mouthpiece and mouthpiece cover where they may be inhaled.

The present invention relates to an inhalation device (1), to the use thereof, and to a kit comprising the inhalation device. The inhalation device (1) has an air inlet (14), an air outlet (15) designed as a mouthpiece or nosepiece, and a recess (17) which is designed to receive a container (2) with an inhalable substance. An air duct (L) extends from the air inlet (14) through the recess (17) to the air outlet (15). Moreover, the inhalation device (1) has at least one hollow mandrel (16, 16′) which protrudes into the recess (17) and from which at least one air delivery line (14′, 14″) extends to the air inlet (14) or at least one air outlet line (15′) extends to the air outlet (15). The inhalation device (1) is characterized in that the inhalation device (1) has two limbs (11, 12), each with a work end (11′, 12′) and with an actuation end (11″, 12″), wherein the limbs (11, 12) are connected by means of a joint (13) which lies between the work ends (11′, 12′) and the actuation ends (11″, 12″). Furthermore, the recess (17) is defined between the mutually facing sides of both limbs (11, 12) at the work ends (11′, 12′), wherein the at least one hollow mandrel (16, 16′) is arranged inside the recess (17) on one of the mutually facing sides of both limbs (11, 12). The air inlet (14) and the air outlet (15) are arranged at the work end (11′, 12′) on a side, directed away from the recess (17), of at least one of the limbs (11, 12).

Adherence monitors are disclosed, incorporating cap removal sensors together with a determined time period in order to determine that a dose of medicament has been dispensed. In another form, cap removal data is combined with acoustic data to determine that a dose of medicament has been dispensed. Several specific structural arrangements are also disclosed.

A nebuliser device with a vibrating mesh, for administering medicaments, includes a casing, a nozzle, a nebuliser and a chamber that houses a medicament. The chamber housing a medicament is a disposable capsule forming an independent body that can be extracted from the casing of the device. The disposable capsule includes a connector for attaching to the nebuliser and to the casing. The connector allow the disposable capsule to be coupled to the nebuliser device or uncoupled therefrom.

A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.

A nebuliser device with a vibrating mesh, for administering medicaments is provided. The nebuliser device includes a casing, a nozzle, a nebuliser and a chamber that houses a medicament. The chamber housing a medicament is a disposable capsule forming an independent body that can be extracted from the casing of the device. The disposable capsule attaches to the nebuliser and to the casing. An attachment between the nebuliser and the casing allows the disposable capsule to be coupled to the nebuliser device or to be uncoupled therefrom.

A powder aerosolization apparatus comprises a housing comprising an outlet adapted to be inserted into a user's mouth and one or more bypass air openings. A receptacle support within the housing supports a receptacle containing a powder pharmaceutical formulation. A puncturing mechanism within the housing creates in the receptacle one or more inlet openings and one or more powder outflow openings, wherein the powder outflow openings have a total area of from 0.2 mm.sup.2 to 4.0 mm.sup.2. Upon a user's inhalation through the outlet, air flows through the one or more bypass air openings and through the receptacle to aerosolize the powder pharmaceutical formulation in the receptacle. In one version, the relative flow parameters between the flow through the one or more bypass openings and the one or more powder outflow openings are selected so that flow of aerosolized pharmaceutical formulation does not occur until a predetermined inhalation flow rate is achieved.

A personal vapor inhaling unit including a microprocessor, memory, and a wireless communication interface is disclosed. An application may control aspects of the personal vapor via the wireless interface. An electronic flameless vapor inhaler unit that may simulate a cigarette has a cavity that receives a cartridge in the distal end of the inhaler unit. The cartridge brings a substance to be vaporized in contact with a wick. When the unit is activated, and the user provides suction, the substance to be vaporized is drawn out of the cartridge, through the wick, and is atomized by the wick into a cavity containing a heating element. The heating element vaporizes the atomized substance. The vapors then continue to be pulled by the user through a mouthpiece and mouthpiece cover where they may be inhaled.

Liquid drug cartridges and an associated inhaler are used to deliver one more separate doses of an aerosolized liquid drug. A cartridge includes a container for storing the liquid drug, an end cap having an ejection opening, a filter element, and a piston that is repositionable relative to the container to selectively eject a volume of liquid drug from the ejection opening. The filter element filters the liquid drug prior to ejection from the ejection opening. The liquid drug cartridge can be coupled with an inhaler that includes an aerosol generator. The aerosol generator includes a vibratable membrane onto which the liquid drug is ejected. The liquid drug is aerosolized by the vibration of the membrane for inhalation by a user.

A nebuliser device with a vibrating mesh, for administering medicaments, includes a casing, a nozzle, a nebuliser and a chamber that houses a medicament. The chamber housing a medicament is a disposable capsule forming an independent body that can be extracted from the casing of the device. The disposable capsule includes a connector for attaching to the nebuliser and to the casing. The connector allow the disposable capsule to be coupled to the nebuliser device or uncoupled therefrom.