A method of treating disorders in a human or animal subject may include heating a material containing a compound to a first temperature to form a heated volume of the material. The method may additionally include heating the heated volume to a higher second temperature to form a dose of vapor including the compound. The method may also include administering the dose of vapor to the subject to treat disorders such as pain. The method may further include pre-heating the material to a preliminary temperature prior to the heating to the first temperature. The heating and pre-heating may be performed with a capsule including two covering layers, each including an electrically conductive material, configured to hold the material therebetween and to generate heat by resistive heating.

Cartridges for vaporizer devices are provided. In one exemplary embodiment, the cartridge can include a reservoir housing, an airflow tube that extends through the reservoir housing, and a folded mesh that is disposed within the airflow tube and includes a plurality of folds. The airflow tube defines a passageway extending therethrough and at least a portion of the airflow tube is permeable to the vaporizable material, in which the permeable portion of the airflow tube is configured to draw vaporizable material from the reservoir housing into the airflow tube for vaporization. The folded mesh is configured to change from a deactivated state to an activated state in response to receiving an electric current, and when in the activated state, the folded mesh is configured to generate an amount of heat that is sufficient to vaporize at least a portion of the vaporizable material drawn from the reservoir housing. Vaporizer devices are also provided.