This invention generally relates to counters and in particular to counters for use with dispensers and to dispensers comprising said counters. More particularly the present invention relates to counters for use with metered-dose dispensers, such as metered-dose inhalers (MDIs). In particular, the present invention provides a counter comprising: a first ring member having a first indicia and being rotatable in increments about an axis, the first indicia indicating a count; a limiting member comprising a limiting mechanism, wherein the limiting mechanism comprises an engaging portion arranged to act radially with respect to the first ring member to contact the first ring member to limit free rotation of the first ring member relative to the limiting member about the axis.

The present invention relates to an inhaler which is appropriate for delivery of medicament in dry powder form used in respiratory diseases, particularly in asthma and chronic obstructive pulmonary disease (COPD). In addition, the present invention relates to an inhaler which includes a blister package appropriate for carrying the medicament in dry powder form and used to realize an effective inhalation.

A tensioning arrangement for an aerosol dispenser is presented where the tensioning arrangement has a conveying tube; an elastic member arranged to store mechanical energy from a substantially axial tensioning movement of the conveying tube; a rotatable member; a transmission mechanism configured to transmit a tensioning rotation of the rotatable member to the tensioning movement of the conveying tube, wherein the transmission mechanism has a cam profile and a cam follower arranged to follow the cam profile, wherein the cam profile has at least one priming structure; and wherein the tensioning arrangement is configured such that the conveying tube makes a temporary priming movement towards an initial position when the cam follower passes each priming structure during the tensioning movement of the conveying tube by means of the tensioning rotation of the rotatable member. An aerosol dispenser is also provided.

A locking mechanism for an aerosol dispenser is presented having a first body structure, a second body structure rotatably attached to the first body structure, a spindle rotatably attached to the second body structure, the spindle having an actuator rotationally cooperating with the first body structure such that rotation of the first body structure relative to the second body structure causes rotation of the actuator and of the spindle, a movable element arranged around the spindle, the spindle being rotatable relative to the movable element, wherein rotation of the spindle causes movement of the movable element along the spindle from an initial position to a final position, and a locking element, wherein in the final position the movable element applies a radial force onto the locking element causing the locking element to bend in the radial direction thereby preventing rotation between the first body structure and the second body structure.

A fluid dispenser comprising a body (1), a fluid reservoir (2), a dispenser member, such as a pump or a valve, mounted on said reservoir (2), and a dose indicator device for indicating the number of doses of fluid that have been dispensed or that remain to be dispensed from said reservoir, the dispenser being characterized in that said dose indicator device includes a first safety system for actuating the dose indicator device once the dispenser has performed a predetermined incomplete actuation stroke, even if the dispenser does not perform the complete actuation stroke.

An inhaler includes a mouth-piece cover, a pressure sensor, a first indicator and a second indicator. The first indicator may be configured to indicate based on a state of the cover, and the second indicator may be configured to indicate based on an output of the pressure sensor. For example, when the mouthpiece cover opens, the first indicator may illuminate and a dose of medication may be transferred from a reservoir to a dosing cup. The second indicator may illuminate if an amount of inhaled medication reaches a predetermined threshold for successful inhalation.

The present disclosure describes a tamper responsive cartridge which can prevent malicious or inadvertent altering of the primary substance before it is consumed by the user, either by an intervening party, or the user itself. As described herein, an altering substance can be contained in a second reservoir, separate from the primary reservoir, and configured to make access to the primary reservoir difficult without also accessing the secondary reservoir.

A nebulizer and a housing part comprising a blocking device as well as use of a blocking device are proposed. The blocking device blocks a rotatable element of a counter device in a defined rotational position until the nebulizer is closed.

Stable composition of anhydrous micronized ipratropium or a pharmaceutically acceptable anhydrous salt thereof and method of making.

An inhaler includes a main body having a canister housing, a medicament canister retained in a central outlet port of the canister housing, and a dose counter having an actuation member for operation by movement of the medicament canister. The canister housing has an inner wall, and a first inner wall canister support formation extending inwardly from a main surface of the inner wall. The canister housing has a longitudinal axis X which passes through the center of the central outlet port. The first inner wall canister support formation, the actuation member, and the central outlet port lie in a common plane coincident with the longitudinal axis X such that the first inner wall canister support formation protects against unwanted actuation of the dose counter by reducing rocking of the medicament canister relative to the main body of the inhaler.