A portable medical ventilator using pulse flow from an oxygen concentrator to gain higher oxygen concentration includes a positive pressure source to deliver pressurized air to the patient and a negative pressure source to trigger the oxygen concentrator. A patient circuit attached to a patient interface mask connects the ventilator to the patient. The ventilator includes a controller module that is configured to generate a signal to the negative pressure device to trigger the concentrator to initiate one or more pulses of oxygen from the oxygen concentrator. The oxygen pulses are delivered to the patient interface directly through multi-tube or a multi lumen patient circuit. The oxygen does not mix with air in the ventilator or in the patient circuit and bypasses the leaks in the patient circuit and/or patient interface.

The present disclosure provides systems and method for electric plasma synthesis of nitric oxide. In particular, the present disclosure provides a nitric oxide (NO) generation system configured to produce a controllable output of therapeutic NO gas at the point of care.

A ventilation apparatus has a breathing gas delivery system for delivering breathing gas to a user of the apparatus as ventilation therapy, with a controllable pressure and flow. The breathing pressure and flow are monitored to derive a respiration variability. A state of relaxation of the user is derived during provision of breathing assistance based on at least the respiration variability. Settings of the ventilation apparatus are then adapted dependence on the estimated state of relaxation for assisting the user in habituating to the breathing assistance, and hence habituating to breathing therapy.

There is a ventilator for mechanical ventilation during a breathing cycle including an inhalation cycle and an exhalation cycle. The ventilator is configurable to be in fluid communication with a supply of a first fluid. The ventilator includes an inhalation pathway and an exhalation pathway. A first fluid injector is in fluid communication with the supply of the first fluid for injecting the first fluid. The inhalation pathway receives the first fluid injected by the first fluid injector. A controller is operatively connected with the first fluid injector and programmed to selectively actuate the first fluid injector to inject the first fluid, which is received within the inhalation pathway such that an inhalation pressure in the inhalation pathway is within a predetermined range during the inhalation cycle.

Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user. The device may suggest a corrective action based on the type of off-target ventilation detected. The device may also continuously analyze ventilation to determine changes in lung compliance over time and to identify pathological changes over time. The device may work within a network of devices and user interfaces via wired or wireless communication, and is not restricted to or dependent on the type of ventilatory device with which a patient is being supported.

The present invention relates to a method and a respiration device having a respiration unit for generating an airflow for the respiration and having a monitoring unit. The monitoring unit is used to detect a respiration parameter and to classify events in the respiration on the basis of monitoring of the respiration parameter. In this case, the monitoring unit is configured to carry out an event analysis to recognize an occurrence, which is characteristic for Cheyne-Stokes respiration, of chronologically successive events and for this purpose to ascertain the period length thereof and to compare them to one another and to register the presence of Cheyne-Stokes respiration when the compared period lengths each deviate by less than 40% from one another.

Resuscitation/ventilation systems that include a pressure chamber or cylinder may use a piston articulated within the pressure chamber or shaft to push air and/or a mixture of gas and air into and out of an airway circuit for the purpose of providing mechanical ventilation and/or artificial respiration to a patient. In some cases, the pressure chamber or cylinder may be resident within a canister that fits with a body. The canister may include a motor that moves a shaft connected to the piston up and down, or in and out, within the pressure chamber or cylinder and this movement of the piston may cause a vacuum within the airway circuit and/or the pushing of air or gas out of the airway circuit into a patient’s lung(s).

Systems and methods for generating and delivering nitric oxide are provided. In one aspect, a nitric oxide generator includes an inlet arranged to receive a gas including nitrogen and oxygen, an outlet, a pair of electrodes arranged downstream of the inlet and configured to generate nitric oxide from the gas, a pressure regulator configured to selectively adjust a pressure of the gas surrounding the electrodes, an accumulator in communication with the pressure regulator, a nitric oxide sensor arranged to measure a concentration of nitric oxide at the outlet, and a controller in communication with the pair of electrodes, the pressure regulator, and the nitric oxide sensor. The controller is configured to selectively instruct the pressure regulator to adjust the pressure of the gas surrounding the electrodes in response to the concentration of nitric oxide measured at the outlet by the nitric oxide sensor.

Methods and apparatus for treating a respiratory disorder, in one aspect, include an apparatus that delivers backup breaths at a sustained timed backup rate that is a function of the patient's spontaneous respiratory rate. Other aspects include apparatus that delivers backup breaths at a rate that gradually increases from a spontaneous backup rate to a sustained timed backup rate or, alternatively, apparatus that oscillates a treatment pressure in antiphase with the patient's spontaneous respiratory efforts when a measure indicative of ventilation is greater than a threshold. Other aspects include apparatus configured to treat Cheyne-Stokes respiration by computing the treatment pressure so as to bring a measure indicative of ventilation of the patient towards a target ventilation that is dependent on the measure indicative of ventilation or, alternatively, by periodically elevating the treatment pressure to a high level for a short time, the high level being high enough and the short time being long enough to induce a central apnea in a patient. Depending on functionality, the foregoing apparatus may comprise an adaptive servo-ventilator or CPAP therapy device.

A nebulizer assembly for a respiratory device is provided having a housing defining a chamber. The housing also has a nebulizer port configured to receive a nebulizer to discharge atomized medication into the chamber. An outlet of a handle is coupled to the inlet of the housing. A hose is coupled to an inlet of the handle. A patient interface is coupled to the outlet of the housing. Air flows from the hose to the patient interface via the handle and the housing. The air mixes with the atomized medication within the chamber.