Systems and methods for triggering inspiration and/or cycling exhalation with a ventilator are described herein. In particular, systems and methods for synchronizing ventilator breath delivery with patient breath demand utilizing a digital sample counting trigger mode are described herein. The digital sample counting triggering mode characterizes digital samples taken from a measured or estimated parameter during the patient inhalation/exhalation period to synchronize breath delivery with patient breath demand.

A ventilator (100) ventilates a patient (102) by a high-flow oxygen therapy via a tube system (104). The ventilator has at least one sensor element (110), at least one actuatable inhalation valve or exhalation valve (120) and a control unit (130). The sensor element is arranged and configured to determine and to output a measured variable (112) within the tube system. The measured variable indicates a gas flow within the tube system. The actuatable inhalation valve or exhalation valve is arranged and configured to make possible a flow of a breathing gas from a ventilation circuit (107) of the ventilator. The control unit regulates a ventilation pressure provided by the ventilator via the at least one sensor element and the at least one inhalation valve or exhalation valve such that a predefined maximum pressure is not exceeded in a predefined area (140) of the tube system.

A filter sterilization system includes an expiratory filter having filter material that collects pathogens present in the exhaled gas stream from a ventilated patient. A filter sterilizer includes an ultraviolet (UV) light source that is activated by the system to emit light towards the expiratory filter. Additionally, the system includes a ventilator coupled to a patient breathing circuit that provides a gas mixture from a gas source to the ventilated patient and transfers exhaled gases of the ventilated patient to the expiratory filter.

A combination respiratory therapy management system creates a combined respiratory therapy prescription that can be executed by a combined respiratory therapy device to provide multiple coordinated respiratory therapies to a patient. The system can update the combined respiratory therapy prescription and implement the updates while the combined respiratory therapy device is in use. Some versions of the system provide additional features that allow the combined respiratory therapy prescriptions to be created, accessed, shared with other users, and performed by the combination respiratory therapy device in a customizable user-friendly and non-threatening way.

An oscillating positive expiratory pressure system including an oscillating positive expiratory pressure device, an adapter coupled to the device, and a control module coupled to the adapter. The control module provides real time information about the use of the device, and provides feedback and storage of the information to improve the use thereof.

Described is a system including a sensor and a processing arrangement. The sensor measures data corresponding to a patient's breathing patterns. The processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of a REM sleep state. In another embodiment, the processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of one of the following states: (i) a wake state and (ii) a sleep state. In another embodiment, a neural network analyzes the data to determine whether the breathing patterns are indicative of one of the following states: (i) a REM sleep state, (ii) a wake state and (iii) a sleep state. In another embodiment, the processing arrangement analyzes the data to determine whether the breathing pattern is indicative of an arousal.

The present disclosure relates to determining a corrected exhaled gas measurement during high flow respiratory therapy. Measuring exhaled gas concentration during high flow respiratory therapy is difficult and inaccurate due to a phenomenon known as flushing. The high flows delivered to the patient flush the dead space in the conducting airways, which causes a dilution effect that results in underestimated or overestimated exhaled gas measurement depending on the gas composition delivered by the high flow system. This can lead to incorrect clinical measurements and diagnoses. Various algorithms are disclosed herein to account for the dilution effect caused by flushing, allowing for the method of measuring gas concentrations to still be used accurately for clinical measurements.

A mechanical ventilation system comprises a mechanical ventilator configured to deliver ventilation to a patient. An electronic controller is programmed to control the mechanical ventilator to perform a mechanical insufflation-exsufflation (MI-E) therapy method including performing a MI-E cycle including: (i) during an insufflation cycle, delivering pressure to the patient at a positive insufflation gauge pressure; (ii) during an exsufflation cycle following step (i), delivering pressure to the patient at a negative exsufflation gauge pressure and detecting whether an upper airway collapse occurs; and (iii) reducing a magnitude of the negative exsufflation gauge pressure if an upper airway collapse is detected in step (ii).

In a method and breathing apparatus for prediction of fluid responsiveness of a subject connected to a breathing apparatus, at least one parameter is monitored that is indicative of a degree of carbon dioxide elimination of the subject, and a positive end expiratory pressure PEEP regulator of the breathing apparatus is operated to apply a PEEP maneuver in which a PEEP applied to the subject is changed from a first PEEP level to a second PEEP level. A processor predicts the fluid responsiveness of the subject based on a change in the monitored parameter, following the change in PEEP.

Disclosed is a ventilator with an apparatus input and an apparatus output and with an airway between the apparatus input and the apparatus output. A breathing gas drive, a non-return valve and a switching valve are arranged in the airway. The non-return valve prevents a flow of breathing gas in a direction from the apparatus output to the apparatus input and the switching valve enables at least temporarily a flow of breathing gas in a direction from the apparatus output to the apparatus input.