A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient includes a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the respiratory gas is controlled by a microprocessor, a mixing area for mixing a first gas and a second gas in the respiratory gas flow pathway, a humidification area downstream of the mixing area and configured for humidifying respiratory gas in the respiratory gas flow pathway, and a heated delivery conduit for minimizing condensation of humidified respiratory gas.

A gas delivery conduit adapted for fluidly connecting to a respiratory gases delivery system in a high flow therapy system, the gas delivery conduit includes a first connector adapted for connecting to the respiratory gases delivery system, a second connector adapted for connecting to a fitting of a patient interface, tubing fluidly connecting the first connector to the second connector where the first connector has a gas inlet adapted to receive the supplied respiratory gas, one of electrical contacts and temperature contacts integrated into the first connector. The gas delivery conduit further can include a sensing conduit integrated into the gas delivery conduit, where the first connector of the gas delivery conduit is adapted to allow the user to couple the first connector with the respiratory gases delivery system in a single motion.

The present invention generally relates to, amongst other things, systems, devices, materials, and methods that can improve the accuracy and/or precision of nitric oxide therapy by, for example, reducing the dilution of inhaled nitric oxide (NO). As described herein, NO dilution can occur because of various factors. To reduce the dilution of an intended NO dose, various exemplary nasal cannulas, pneumatic configurations, methods of manufacturing, and methods of use, etc. are disclosed.

A patient interface (1) is for aerosol treatment, having a base (2) to surround the patients mouth and nose and engage the skin with a resilient seal, and with a strap (8) to attach to a patients head. There is a support (3) on and across the base for supporting an aerosol delivery head with prongs (4, 5). An enclosed volume is formed in the interface by attachment of a shell (10), which has an extraction port (11) for attachment of an extraction system (20) to extract gas from this volume. An HFNT system includes a patient interface surrounding the nose and mouth and an aerosol delivery apparatus (4, 6), an extraction apparatus (20), and a controller (100) to control delivery of aerosol and/or gas to the interface and to extract gases from a volume enclosed by the interface. Because of the fully sealed volume within the interface there are a wide range of control scenarios possible, using pressure sensing in the volume, bypass valves (201), dynamically-controllable nebulizer (203).

Nasal cannulas for providing respiratory therapy to patients can have a body, two prongs extending from the body, and a gases inlet on one side of the body. There can be a throttle or internal localized reduction in the cross-sectional area of a cavity defined by the internal walls of the cannula body in between the prongs. In at least some arrangements, the throttle can partially or substantially fully equalize flow between the prongs of the cannula.

A portable oxygen concentrator designed for medical use where the sieve beds, adsorbers, are designed to be replaced by a patient. The concentrator is designed so that the beds are at least partially exposed to the outside of the system and can be easily released by a simple user-friendly mechanism. Replacement beds may be installed easily by patients, and all gas seals will function properly after installation.

A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient, the system including a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the pressurized respiratory gas is controlled by a microprocessor.

Described herein are various embodiments of an oxygen concentrator system and method of delivering oxygen enriched gas to a user. In some embodiments, oxygen concentrator system includes one or more components that improve the efficiency of oxygen enriched gas delivery during operation of the oxygen concentrator system. In some embodiments, time measurements based on the penultimate breath taken by the user are used to alter the oxygen delivery parameters.

The device of the invention is equipped with a pressure sensor and a control unit, and the control unit judges a point at which a pressure gradient calculated from a signal of the pressure sensor becomes larger in the absolute value than a pressure gradient threshold as an inspiration sensing point and starts respiratory gas supply. In addition, the device judges from a frequency of the inspiration sensing point during predetermined time whether a pressure gradient threshold used as a criterion for the inspiration sensing point corresponds to an activity state of the user, and when the pressure gradient threshold does not correspond to the activity state, switches the pressure gradient threshold to another threshold and thus fits the pressure gradient threshold to the activity state.

An oxygen concentrator (100) apparatus and a method thereof implement operations control to efficiently release oxygen enriched gas to reduce potential waste. The control methodology may include generating a profile such as a minimum inhalation flow profile of the user. The profile may be based on a size parameter of the user. The method may determine one or more control parameters characterizing a bolus of oxygen enriched gas based on the generated flow profile. The control methodology may then generate a bolus release control signal, such as for a supply valve, according to the determined one or more control parameters. The oxygen concentrator may then, with the control signal, release and deliver a bolus of oxygen enriched gas for a user such as for reducing waste.