A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.

A fluid supply warning and communication system including a digital regulator in fluid tight engagement with a primary fluid reservoir. A method of using the fluid supply warning and communication system by flowing a fluid from a primary fluid reservoir to an end use appliance and detecting flow rate and pressure of the fluid with a digital regulator. A gas supply warning and communication system including an oxygen flow monitor that monitors SpO2, flow rate, pulse rate, and battery levels. A method of using the gas supply warning and communication system by flowing oxygen from a primary gas reservoir to an end use appliance, and measuring SpO2, flow rate, pulse rate, tank status, and battery levels.

A breathing assistance apparatus is configured with features that improve serviceability of the apparatus. The apparatus can include animations to provide instruction regarding correcting easily-identified fault conditions and to provide instruction regarding routine maintenance routines. The apparatus also can be configured with top level control menus that are obscured in a manner to limit manipulation of the top level control elements by unauthorized users.

An information display and control system that enables a fast and easy understanding and management of the status of the patient's dialysis is disclosed. Also disclosed is an information display and control system that enables a fast and easy understanding and management of the status of the patient's cardiovascular and ventilation systems. The system can control management of a patient's dialysis, as well as administration and management of a patient's medication and fluids. The display is organized by goals related to management of patient's dialysis machine, blood flow, dialyzer flow, and patient's body weight. The display is also organized by goals related to management of patient's cardiovascular system, ventilation system, and medications and fluids administration and management. Such goals include urea reduction rate, urea reduction ratio, fractional urea clearance, total urea reduction, dialysis treatment duration, hemodynamics, oxygenation, CO.sub.2 removal, medication status, and fluids status.

A passive oxygen mask and vacuum regulation system disposed in fluid communication with a vacuum scavenging array includes a passive oxygen mask dimensioned to fit over a patient's nose and mouth and having a gas inlet port and an expired gas outlet port. A vacuum regulation assembly has a vacuum regulator which includes an expired gas discharge tube disposed in fluid communication between the passive oxygen mask and the vacuum regulation assembly, and a vacuum suction tube disposed in fluid communication between the vacuum regulation assembly and the vacuum scavenging array. The vacuum regulation assembly further comprising a vacuum attenuation port through a portion of a regulator housing, wherein the vacuum attenuation port is at least partially defined by an attenuation port diameter dimensioned to reduce a vacuum suction pressure in the expired gas discharge tube to a predetermined vacuum suction pressure.

A ventilator includes a bidirectional breath detection airline and a flow outlet airline. The flow outlet airline includes an airline outlet. The flow outlet airline is configured to be connected to an invasive ventilator circuit or a noninvasive ventilator circuit. The breath detection airline includes airline inlet. The airline inlet is separated from the airline outlet of the flow outlet airline. The ventilator further includes a pressure sensor in direct fluid communication with the breath detection airline. The pressure sensor is configured to measure breathing pressure from the user and generate sensor data indicative of breathing by the user. The ventilator further includes a controller in electronic communication with the pressure sensor. The controller is programmed to detect the breathing by the user based on the sensor data received from the pressure sensor.

Methods and apparatus, such as a controller of a respiratory therapy device, generate a signal representing an estimate of flow rate of gas flow from the device. The respiratory therapy device may include a motor-operated blower. The method may include receiving in the controller, signals generated by a set of sensors, including measures of pressure and frequency (e.g., speed) of the motor. The controller may be configured to compute an entrained air density function and generate the estimate signal based on a function of the measures of pressure and frequency, and the entrained air density function. The entrained air density function may apply signals from additional sensors, such as atmospheric pressure, gas temperature, and ambient relative humidity, to compute atmospheric density. Control operations of the therapy device may then be based on the estimated signal, which may be applied to assess accuracy of a signal from a flow sensor.

The present disclosure relates to a monitoring device for measuring and monitoring breathing parameters and, optionally, oxygenation and/or vital sign parameters of a mechanically ventilated patient, the monitoring device being removably arrangeable at a portion of a ventilator breathing circuit provided between and in fluid connection with a mechanical ventilator and an airway of the patient. The monitoring device comprises a first sensor arrangeable at the fluid connection for measuring parameters related to an airflow in the fluid connection to obtain measurement data; a processor adapted to receive the measurement data from the first sensor and configured to process the measurement data into at least one breathing parameter; and a transmitter adapted to transmit data comprising the at least one breathing parameter to an external device.

Provided are a method for controlling oxygen-containing gas output by an oxygen provider, The method includes: acquiring a first pressure measurement of the oxygen-containing gas at the oxygen provider side; determining a pressure estimation of the oxygen-containing gas at the patient side based on the first pressure measurement, wherein the oxygen-containing gas experiences a pressure drop on the gas pathway to arrive at the patient side; and controlling a target parameter of the oxygen-containing gas output by the oxygen provider based on the pressure estimation. With the method or device for controlling oxygen-containing gas output by an oxygen provider, an automated solution to control the oxygen-containing gas based on a pressure measurement at the oxygen provider side is provided, and the complexity of a medical device for oxygen therapy is reduced.

Systems and methods for producing nitric oxide (NO) to be used in medical applications are provided. In some embodiments, systems and methods are provided for a NO generator that is capable of generating a desired concentration of NO to be provided to a respiratory system for inhalation by a patient.