An apparatus for delivery of a flow of gases to a user, such as a respiratory therapy apparatus, is provided. The apparatus may have first and second inlets for receiving supplementary gases flows, a blower to generate the gases flow to the user, and a controller. A valve and a sensor may be provided in the second inlet. The controller may be configured to detect the disconnection of a gases source from the second inlet, and to respond by operating the valve and/or triggering an alarm. The controller may be configured to determine whether a gases flow is being provided at one or both of the inlets, and to accordingly control an operational mode of the apparatus.

A compressor assembly for a portable oxygen concentrator includes a first compressor chamber having a first connector, a second compressor chamber having a second connector, and a tube having a first end having a first connection interface configured to connect to the first connector and a second end having a second connection interface configured to connect to the second connector. The first connection interface is shaped to maintain the connection between the first connector and the first connection interface in a fixed orientation and the second connection interface is shaped to maintain the connection between the second connector and the second connection interface in a fixed orientation. One or more of the first connector, the second connector, and the tube are compliant.

Systems and methods for generating MRI images of the lungs and/or airways of a subject using a medical grade gas mixture comprises between about 20-79% inert perfluorinated gas and oxygen gas. The images are generated using acquired .sup.19F magnetic resonance image (MRI) signal data associated with the perfluorinated gas and oxygen mixture.

A medical gas delivery system and a ventilator system are provided. The medical gas delivery system includes an electrolytic gas generation device, a delivery device, and a control unit. The electrolytic gas generation device is used to generate a first gas and a second gas. The delivery device is in fluid communication with the electrolytic gas generation device, and is used to transport a medical gas. The medical gas includes at least one of the first gas and the second gas. The control unit is electrically connected with the electrolytic gas generation device and the delivery device, so as to control a component ratio of the medical gas.

A therapy of oxygen pulses delivered through the pulmonary system of human patient for treating neurodegenerative disorders such as Parkinson Disease (PD), Alzheimer's Disease (AD), Amiotrophic Lateral Sclerosis (ALS) or Motor Neuron Disease (MND) and other dementias, and Lymphedema, Arthritis and Depression is provided. Aspects of the methods including administering to the subjects an effective amount of oxygen as pulses through the respiratory tract are included. Also provided are methods of assessing severity of the disease, mild, moderate, severe, or critical, and oxygen doses and frequencies. The method can be applied to human patient for treating neurodegenerative disorders such as Parkinson Disease (PD), Alzheimer's Disease (AD) Amiotrophic Lateral Sclerosis (ALS) or Motor Neuron Disease (MND) and other dementias, and Lymphedema, arthritis and depression.

The disclosure relates to a method and respiratory system, comprising: a flow generator to provide a gas-flow to a patient, the gas flow comprising an oxygen fraction, and a controller configured to: receive input relating to oxygen fraction at a patient's nose and/or mouth, adjust the gas-flow flow rate based on the oxygen fraction at the patient's nose and/or mouth.

An oxygen concentration system may comprise a pressure sensor, a movement sensor, and a controller configured to use one or more pressure signals obtained from the pressure sensor and a movement signal obtained from the movement sensor to determine when to release a bolus of oxygen enriched air. In some implementations, the controller may adjust a trigger threshold based on an initial pressure signal obtained from the pressure sensor and the movement signal obtained from the movement sensor. In some implementations, the controller may adjust a pressure signal obtained from the pressure sensor based on the movement signal obtained from the movement sensor. In some implementations, the controller may detect a potential onset of inhalation from a pressure signal obtained from the pressure sensor and determine whether to verify the potential onset of inhalation based on the movement signal obtained from the movement sensor.

Systems and methods for managing the power consumption of an oxygen concentrator are disclosed. An oxygen concentration system may comprise a compression system, a canister system, one or more processors, and at least one of a pressure sensor or a movement sensor. The one or more processors may be configured to transition the oxygen concentration system to at least one of a prescribed mode of operation or a standby mode of operation. The timing of the transition may be based on at least one of a number of breaths detected from the pressure signals generated by the pressure sensor or an estimated energy content of the movement signal generated by the movement sensor. A predetermined volume or concentration of oxygen enriched air may be supplied to a user during the prescribed mode of operation. A reduced power may be provided to the compression system during the standby mode of operation.

Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user. The device may suggest a corrective action based on the type of off-target ventilation detected. The device may also continuously analyze ventilation to determine changes in lung compliance over time and to identify pathological changes over time. The device may work within a network of devices and user interfaces via wired or wireless communication, and is not restricted to or dependent on the type of ventilatory device with which a patient is being supported.

An interface component of a flow therapy device includes a communication module configured to communicate with one or more physiological sensors and one or more computing devices. The communication module receives data from the physiological sensors and/or computing devices. A processor of the interface component processes the data and generates one or more outputs. The processor generates user interface data based on the received data for a display of the interface component to render user interfaces. The processor may also generate one or more auditory signal alarms on a speaker of the interface component. A user may control the operation of the interface component or the flow therapy device remotely using, for example, a remote computing device in wireless communication with the communication module. A user may control the operation of the interface component or the flow therapy device via the display of the interface component.