A connection device and process connect a patient-side coupling unit to a source/sink of a gas including oxygen. The connection device includes a valve device with a first valve (40.1) and with a second valve (40.2). A source-side fluid guide unit establishes a fluid connection between the source or the sink and the valve device. A patient-side fluid guide unit establishes a fluid connection between the patient-side coupling unit and the valve device. The valves are connected in parallel and are arranged between the two fluid guide units. A gas flows from the source through the first and/or second valve to the patient-side coupling unit or through the first and/or second valves to the sink. A control pressure is set at each valve. As a result, the time course of the volume flow downstream of the valve device follows a predefined time course.

Aspects of the invention include devices, systems, and methods for enhancing a user's sleep. A flexible frame supports a flow manifold which can be used in unison with adjoined or adjacently integrated supportive members utilized to create soft objects of various designs and materials. These types of objects can be in the form of a pillow, mattress topper, even a child's stuff animal and other various stationary and portable soft sided padded embodiments as disclosed in this application. These various designs and embodiments house an integrated flow delivery system which is delivers concentrated, pressurized, and or altered gaseous flowing elements in a controlled and fluidic manner as to help address certain types of sleeping and breathing issues during their resting and sleep states.

Provided is a ventilator that includes a breathing system, a mechanical system coupled to breathing system, and a control system coupled to breathing system and mechanical system. The control system includes pressure sensors, processing circuitry, and memory configured to store a look-up table. The processing circuitry receives a set of values for plurality of parameters, identifies a compression value from a plurality of compression values in the look-up table based on the received set of values. The processing circuitry causes the mechanical system to compress a bag valve of the breathing system in accordance with the identified compression value. The compression of the bag valve causes a gaseous inhalant to flow through the breathing system within a time-interval. The processing circuitry determines an actual volume of the gaseous inhalant and iteratively modifies the compression value of the bag valve to match a desired volume of the gaseous inhalant.

A respiration device (1) supports cardio-pulmonary resuscitation (CPR) and a method for operating a respiration device (1) supports cardio-pulmonary resuscitation (CPR). The respiration device (1) has a control and regulation unit (7) in order to actuate an expiratory metering unit (3), and an inspiratory metering unit (2) such that, in a first phase, a current value of pressure is increased relative to a first pre-defined value (16) and such that, in a second phase, the current value of the pressure is reduced relative to the first pre-defined value (16).

A respiratory flow therapy apparatus including a sensor module can measure a flow rate of gases or gases concentration provided to a patient. The sensor module can be located after a blower and/or mixer. The sensor module can include at least an ultrasonic transmitter, a receiver, a temperature sensor, a pressure sensor, a humidity sensor and/or a flow rate sensor. The receivers can be immersed in the gases flow path. The receivers can cancel delays in the transmitters and improve accuracy of measurements of characteristics of the gases flow. The receivers can allow for detection of a fault condition in a blower motor of the apparatus.

Disclosed herein are methods, systems, and devices for controlling a gas mixture within a mechanical ventilator. According to one embodiment, a computer implemented method includes receiving first peripheral arterial oxygen saturation (SpO.sub.2) data from a pulse oximeter via a pulse oximeter interface, wherein the pulse oximeter is configured to monitor a patient receiving invasive ventilation; determining a first mode of operation for a ventilator mechanism, wherein the ventilator mechanism is configured to provide at least a portion of the invasive ventilation; determining first partial pressure of oxygen (PaO.sub.2) data stored in a first lookup table using the first SpO.sub.2 data, wherein the first lookup table is derived from a sigmoid shaped oxyhemoglobin dissociation curve; determining first fraction of inspired oxygen in air (FiO.sub.2) data for setting a mixture in a gas blender in the ventilator mechanism based on the first PaO.sub.2 data and a variable offset; and providing the FiO.sub.2 data to the ventilator mechanism.

Systems and methods for hypoxia delivery are provided. An apparatus for providing intermittent normoxia and hypoxia intervals includes a breathing component, a normoxia fluid source, a hypoxia fluid source, a valve, and a control system. The valve is configured to disrupt flow from at least one of the normoxia fluid source and the hypoxia fluid source and the control system is configured to cause the at least one valve to switch between delivery of fluid from the normoxia fluid source and the hypoxia fluid source while maintaining positive pressure at the breathing component.

Embodiments of the innovation relate to a ventilator, comprising: a positive displacement pump having a drive motor and configured to output a predetermined volume of inspiratory gas for each rotation of an output shaft of the drive motor; at least one pressure sensor configured to measure inspiratory pressure; and a control unit having a controller comprising a memory and a processor, the control unit disposed in electrical communication with the drive motor and with the at least one pressure sensor. The controller is configured to: receive at least one of an operation signal and a pressure sensor signal, and transmit a drive motor control signal to the drive motor to adjust at least one of a rotational speed of the output shaft and a number of rotations of the output shaft based upon the at least one of the operation signal and the pressure sensor signal.

A dry powder aerosol delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The dry powder aerosol delivery device includes a housing, a cartridge, and a dry powder dispersion mechanism, and at least one differential pressure sensor. The dry powder delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The dry powder aerosol delivery device is then actuated to generate a plume of particles having an average ejected particle diameter within the respirable size range, e.g., less than about 5-6 μm, so as to target the pulmonary system of the user.

An aerosol generating system for generating a respirable dry powder aerosol from a liquid solution or liquid suspension, having: a liquid aerosol generating nozzle having a nozzle input end designed to receive the liquid solution or liquid suspension, and having a nozzle heliox supply designed to receive nozzle heliox, the liquid aerosol generating nozzle further having a nozzle output end for outputting a liquid aerosol suspended in the nozzle heliox; and a cylindrical evaporation chamber having a cylindrical evaporation chamber input end that is connected to the nozzle output end and connected to a dilution heliox supply for receiving both the liquid aerosol suspended in the nozzle heliox and for receiving the dilution heliox, and the cylindrical evaporation chamber having a cylindrical evaporation chamber output end outputting a first intermediate dry powder aerosol at a first intermediate dry powder aerosol volume flow of a specific concentration.