A system for delivering oxygen comprises an oxygen source; a ventilator operatively connected to the oxygen source to receive a supply of oxygen therefrom; a valve having a) an open position in which the ventilator receives the supply of oxygen from the oxygen source and b) a closed position in which the ventilator is not in fluid communication with the oxygen source; a sensor configured to measure breath flow information for the patient; and a computer system to: determine a volume of gas delivered to the patient during a breath cycle of the patient and an inspiratory volume of gas delivered to the patient during an inspiration phase of the breath cycle by using the breath flow information; and provide input to the valve based on the determined volumes, the provided input causing a movement of the valve between the open and the closed positions.

A respiratory therapy system can have a flow generator adapted to provide gases to a patient. A gas passageway can be located in-line with the flow generator. The gas passageway can have a first portion adapted to receive a first gas and a second portion adapted to receive a second gas. The gas passageway can have a static mixer downstream of the first and second portions.

The present invention includes an apparatus and method for breaking up mucus in a lung comprising: a chamber having an inlet and an outlet; a pressure oscillating unit in fluid communication with the chamber for supplying and vacuuming air into/out of the chamber, wherein the pressure oscillating unit creates ultrasound waves; a control unit for selecting a positive air pressure or a negative air pressure from the pressure oscillating unit, a fluid container in fluid communication with the chamber; a pressure sensor in fluid communication with the chamber; and an outlet connected to the chamber to send respiration gas to a patient, ultrasonic waves in the respiration gas are capable of breaking up mucus in the lung.

Systems and methods are provided for delivering one or more drugs. In some embodiments, a drug delivery system includes a housing having a distal end with an inlet through which an inspiratory flow of air passes into the housing, a proximal end having a patient interface attached thereto, the patient interface being configured to interface with a user, and an inspiratory flow pathway extending from the distal end to the proximal end of the housing. A nitric oxide (NO) source is positioned within the housing and is configured to deliver NO-containing gas to the patient interface. A secondary drug source is positioned within the housing and is configured to deliver a secondary drug to the patient interface. A controller is configured to control an amount of NO-containing gas and an amount of the secondary drug delivered using a control scheme.

A personal respiratory isolation system (PRIS) provides a personal, negative pressure environment for a patient or user that reduces contamination and spread of pathogens exhaled by the patient into the environment. The PRIS includes an enclosure to receive the patient's head (such as a hood and a drape) and a negative pressure source which draws ambient air into the interior of the enclosure and draws air within the enclosure's interior (including the exhalations of the patient, including any contaminants and/or pathogens) out of the enclosure via a fluid port into a container for biohazard processing or disposal. The PRIS may allow positive air pressure therapeutic treatments to be delivered to the patient within the negative pressure environment, and the PRIS may maintain a constant pressure within the interior of the enclosure. The PRIS may include a transparent, hinged face shield for ease of patient observation and/or access.

A respiratory delivery system providing a bi-level pressure airflow. The system includes respiratory and pneumatic circuits. The respiratory circuit includes a respiratory gas supply, a patient interface, and a bi-level pressure regulator. The respiratory gas supply supplies a respiratory gas to the patient interface via a first conduit. The bi-level pressure regulator is coupled to the patient interface via a second conduit and is configured to cyclically alternate the respiratory gas passing through the bi-level pressure regulator between a low-pressure level and a high-pressure level. The pneumatic circuit includes a pneumatic gas supply and a pneumatic cycler configured to output a cycling pressure level. The cycler is coupled to the bi-level pressure regulator via a third conduit. The bi-level pressure regulator cyclically alternates the pressure level of the respiratory gas between the low-pressure level and the high-pressure level with the timing defined by the cycling of the pneumatic gas.

An apparatus for applying positive pressure nebulized liquid to a patient includes a funneled T-connector having a funnel with a first opening of a first diameter, a second opening of a second diameter smaller than the first diameter, and a funnel wall extending between the first and second openings. The funneled T-connector further has a cylindrical nebulizer port that extends outwardly from the funnel wall. A nebulizer cup assembly includes a nebulizer cup to contain liquid and a nebulizer cap to removably attach to a top region of the nebulizer cup. The nebulizer cap has a cylindrical nebulizer outlet sized to removably attach to the cylindrical nebulizer port. The cylindrical nebulizer outlet extends upwardly through the nebulizer passage, beyond the cylindrical nebulizer port, and into the internal funnel space such that a top edge of the cylindrical nebulizer outlet is located within the internal funnel space.

A system for providing continuous positive air pressure therapy is provided. The system includes a flow generator, a sensor, and a computing device. The computing device is configured to control operation of the flow generator based on sensor data. The computing device is further configured to display, on a display device, one or more questions relating to demographic and/or subjective feedback; responsive to displaying the one or more questions, receive one or more inputs indicating answers to the one or more questions; transmit the answers to a remote processing system; receive, from the remote processing system, settings determined based on the transmitted answers; and adjust control settings of the system based on the received settings.

Disclosed herein are methods, systems, and devices for controlling a gas mixture within a mechanical ventilator. According to one embodiment, a computer implemented method includes receiving first peripheral arterial oxygen saturation (SpO.sub.2) data from a pulse oximeter via a pulse oximeter interface, wherein the pulse oximeter is configured to monitor a patient receiving invasive ventilation; determining a first mode of operation for a ventilator mechanism, wherein the ventilator mechanism is configured to provide at least a portion of the invasive ventilation; determining first partial pressure of oxygen (PaO.sub.2) data stored in a first lookup table using the first SpO.sub.2 data, wherein the first lookup table is derived from a sigmoid shaped oxyhemoglobin dissociation curve; determining first fraction of inspired oxygen in air (FiO.sub.2) data for setting a mixture in a gas blender in the ventilator mechanism based on the first PaO.sub.2 data and a variable offset; and providing the FiO.sub.2 data to the ventilator mechanism.

Systems and methods for calibrating oxygen sensors in ventilators are provided. An oxygen sensor is coupled in flow communication with a first oxygen gas source. A calibration circuit including a second oxygen gas source is coupled in flow communication with the oxygen sensor and a third oxygen gas source is coupled in flow communication with the oxygen sensor. A controller is configured to determine a calibration curve for the oxygen sensor via the calibration circuit by measuring the second oxygen gas source and the third oxygen gas source. Based on the calibration curve, an oxygen concentration value of the first oxygen gas source is measured and distributed.