Systems and method for conducting respiratory therapy in a respiratory system can adjust a flow of respiratory gases to a patient based upon a detected patient breath cycle. The respiratory system can include a non-sealed patient interface. The respiratory system can be configured to deliver a high flow therapy. A patient breath cycle may be determined using one or more measured parameters, such as a flow rate, a blower motor speed, and/or a system pressure. A flow source may be adjusted to have a phase matching that of the patient's breath cycle, such that flow in increased in response to the patient inhaling, and decreased in response to the patient exhaling.

A humidifier for humidifying a flow of pressurized breathable gas to be delivered to a patient includes a dock and a humidification tub. The dock includes a device compartment that is configured to at least partially removably receive an RPT device that is configured to supply the flow of pressurized breathable gas. The dock also includes a humidification compartment that is fluidly connected to the device compartment. The humidification tub is configured to contain a supply of water and is at least partially removably received within the humidification compartment so that, in an operational configuration, the humidification tub is arranged to receive the flow of pressurized breathable gas and output the flow of pressurized breathable gas with increased humidity. The dock also includes a heater fixed to the humidification tub. The heater is configured to heat the supply of water.

A heated conduit is configured to be connected to and receive pressurized breathable gas from a respiratory unit. The heated conduit includes a first cuff configured to be attached to the respiratory unit, the first cuff comprising a tubular air inlet portion that is configured to receive the pressurized breathable gas and an electrical connector portion that is adjacent to the tubular air inlet portion and comprises three electrical terminals. The three electrical terminals are configured to engage an electrical connector of the respiratory unit. A grouping of wires are supported within a helical rib of a flexible tube portion. The grouping of wires includes a pair of heating wires configured to generate heat and a signal wire configured to carry the signal that is output by a sensing device. Each of the heating wires and the signal wire is connected to a corresponding one of the three electrical terminals of the electrical connector portion of the first cuff.

A heated conduit is configured to connect to and receive pressurized breathable gas from a respiratory unit. The heated conduit includes a first cuff that includes an air inlet portion and an electrical connector portion that is adjacent the air inlet portion and comprises three electrical terminals that are configured to engage a respiratory unit electrical connector. The heated conduit also includes a second cuff comprising an air outlet and a flexible tube portion with a first end connected to the first cuff, a second end connected to the second cuff, and a spiral rib structure wrapped around a central lumen. A grouping of wires is supported within the spiral rib structure of the flexible tube portion and include a pair of heating wires and a signal wire. A sensing device extends into the gas flow path from an interior surface of the second cuff and is configured to output a signal indicative of the condition inside the heated conduit.

A system for performing cold atmospheric plasma treatment of respiratory infections or lung cancer having a source of a carrier gas, a cold atmospheric plasma generator connected to the source of carrier gas, a source of compressed air, a humidifier connected to the source of compressed air, a source of oxygen, a ventilator having inputs connected to an output of the humidifier and the source of oxygen, a mixer having an interior chamber formed from a dielectric, an active electrode inside the interior chamber, and an outer electrode connected to ground, wherein the mixer has a fluid input port connected to a gas output of the cold atmospheric plasma generator and an output of the ventilator, and a delivery member connected to an output of the mixer for delivering combined humidified air and cold atmospheric plasma to a respiratory system of a patient.

Humidifier apparatus for a respiratory apparatus includes a housing providing a gas flow path, a heater apparatus, and a water supply distribution member configured and arranged to deliver water vapour to the gas flow path. The water distribution member is provided to the housing and in thermal communication with the heater apparatus.

A breathing assistance apparatus is configured with features that improve serviceability of the apparatus. The apparatus can include animations to provide instruction regarding correcting easily-identified fault conditions and to provide instruction regarding routine maintenance routines. The apparatus also can be configured with top level control menus that are obscured in a manner to limit manipulation of the top level control elements by unauthorized users.

An aerosol delivery system has a nebulizer and a humidifier providing a gas flow to the nebulizer. A controller varies humidity level of the gas flow to the nebulizer so that if the nebulizer is not operating it has about 100% humidity and it is operating the value is less to allow for the humidification effect of the nebulizer. The control may be achieved by dynamically varying proportions of flow through a dry branch and a humidification branch.

A drug delivery device (400) comprises a tip (416) configured to be positioned in a nose of a patient, the tip having an opening (414) therein, a coupling mechanism (402) configured to releasably couple to a first vial (404) containing a first drug therein, to release the first vial therefrom, and to subsequently be releasably coupled to a second vial containing a second drug therein, and a plunger configured to be actuated to cause the first drug to exit through the opening and to be subsequently actuated to cause the second drug to exit through the opening. The same drug delivery device is therefore configured to deliver multiple doses. There are also disclosed various exemplary reloadable drug vials for multi-dose delivery, drug products utilizing the same, and methods of using reloadable drug vials for multi-dose delivery.

This invention relates to a connector for a component of a medical breathing circuit. The connector comprises an inner body and an outer body. The inner body and the outer body being separate components. The inner body having a retention mechanism configured to engage another connector, and an outer body configured to at least partly surround the inner body, the outer body having a tube engagement mechanism.