Various exemplary drug syringes with a mechanical stop for a second dose, drug products utilizing the same, and methods of using drug syringes with a mechanical stop for a second dose are provided. In general, a nasal drug delivery device is configured to dispense therefrom first and second doses of a drug therefrom into a nose. The drug delivery device includes a mechanical stop configured to provide a pause between the delivery of the first and second doses. During the pause, a user of the drug delivery device can move the drug delivery device from one nostril, into which the first dose was sprayed, to another nostril, into which the second dose can be sprayed. The mechanical stop is configured to hold the drug delivery device in a static delivery state.

Various exemplary drug holders (102, 200) for drug delivery devices (100), drug products utilizing the same, and methods of using drug holders for drug delivery devices are provided. In general, a nasal drug delivery device is configured to dispense therefrom at least one dose of a drug therefrom into a nose. The drug delivery device includes a drug holder that contains the drug therein that is delivered out of the drug delivery device. The drug holder can include two cavities (208, 210) therein that are fluidically sealed from one another prior to use of the drug delivery device to cause drug delivery. A first one of the cavities includes the drug therein, and a second one of the cavities includes a drug or air therein.

A method includes receiving data associated with a user during a sleep session. The received data is analyzed to determine, for a selected timeframe during the sleep session, whether the user is breathing through nostrils of the user. Based at least in part on a result of the analysis, a mask recommendation is communicated.

A humidifier includes a heating element including a porous structure of electrically resistive and thermally conductive material configured to substantially vaporise liquid that is passed through the porous structure. The porous structure has a liquid inlet and a vapour outlet. The humidifier further includes an outer housing surrounding at least a portion of the porous structure for containing the liquid and vapour within the porous structure. The porous structure includes a first electrical connector and a second electrical connector, the first and second connectors being configured for receiving electrical power and applying a voltage across the porous structure to generate heat.

A breathing assistance apparatus is configured with features that improve serviceability of the apparatus. The apparatus can include animations to provide instruction regarding correcting easily-identified fault conditions and to provide instruction regarding routine maintenance routines. The apparatus also can be configured with top level control menus that are obscured in a manner to limit manipulation of the top level control elements by unauthorized users.

An apparatus for humidifying a flow of pressurised, breathable air includes varying a first pressure of the flow of breathable gas to vary a level of thermal engagement between the conductive portion of the reservoir and the heater plate, varying a height of the variable portion varies a level of thermal engagement between the conductive portion of the reservoir and the heater plate, use of a humidifier reservoir base component with a maximum water capacity substantially equal to the predetermined maximum volume of water of the humidifier reservoir or the use of intersecting inlet and outlet axes.

Introduced are methods and systems for an adjustable bed device configured to: gather biological signals associated with multiple users, such as heart rate, respiration rate, or temperature; analyze the gathered human biological signals; and heat or cool a bed based on the analysis.

A system (10) configured to facilitate humidification of a pressurized flow of breathable gas delivered to a subject (12) comprises a pressure generator (14), a nebulizer (16), a heater (38), one or more hardware processors (22), and/or other components. The pressure generator is configured to generate a pressurized flow of breathable gas for delivery to an airway (24) within a trachea of the subject. The nebulizer is configured to provide fluid droplets (54) to the breathable gas. The heater is configured to heat a volume of the breathable gas before the droplets are supplied to the breathable gas. The breathable gas received by the subject exhibits a target temperature and humidity level at short distance d from the nebulizer due to one or more of a number of the droplets, an average size of the droplets, a gas flow rate, and/or an amount of heating power.

Systems and methods for nitric oxide (NO) generation systems are provided. In some embodiments, an NO generation system comprises at least one pair of electrodes configured to generate a product gas containing NO from a flow of a reactant gas. The electrodes have elongated surfaces such that a plasma produced is carried by the flow of the reactant gas and glides along the elongated surfaces from a first end towards a second end of the electrode pair. A controller is configured to regulate the amount of NO in the product gas by the at least one pair of electrodes using one or more parameters as an input to the controller. The one or more parameters include information from a plurality of sensors configured to collect information relating to at least one of the reactant gas, the product gas, and a medical gas into which the product gas flows.

A method includes emitting an acoustic signal into an airway of a user. The method further includes, detecting an acoustic reflection of the acoustic signal caused by one or more physical features within the airway of the user. The method also includes analyzing acoustic data associated with the acoustic reflection. The method also further includes characterizing an occurrence of the physical obstruction in the airway of the user. The characterization is based, at least in part, on the analyzed acoustic data. The characterization is indicative of an apnea event or a hypopnea event in the user, wherein the apnea event comprises an obstructive apnea event, a central apnea event or a mixed apnea event, and further distinguishes between the occurrence of the obstructive apnea event, the central apnea event, the mixed apnea event or the hypopnea event in the user.