Methods and apparatus involve generation of an anti-infection therapy. The method/apparatus may include a controller controlling setting of a respiratory flow therapy device for the therapy. The controller may compute a target flow rate profile for a patient using a margin function, such that the target flow rate profile, according to the margin function, exceeds a minimum inspiratory flow rate profile of the patient's inspiration. The controller may control setting the respiratory flow therapy device to generate a flow of air to a patient interface according to the target flow rate profile, where the generation may be in synchrony with a sensed parameter that is indicative of a breathing cycle of the patient.

Methods and systems are provided for an oxygen sensor included in a medical gas flow device, such as an anesthesia machine. In one embodiment, a method for a medical gas flow device comprises tracking an output voltage of an oxygen sensor during calibration over time, and, responsive to the output voltage decreasing by at least threshold amount from an initial calibration output voltage, estimating an end-of-life date of the oxygen sensor and outputting a replacement notification.

The present disclosure relates generally to medical devices and, more particularly, to a gas mixing system for a medical ventilator. A gas mixer is provided to adjust the oxygen concentration of environmental air for a blower-based ventilator, by adjusting the mix of air upstream of the ventilator and providing the mixed air to the ventilator's environmental air inlet.

The present disclosure relates to a breathing assistance apparatus for providing a breathing assistance to a user. The breathing assistance apparatus includes a first/second source configured with a first/second buffer. The first/second fluid is controllably transferred from the first/second source to the first/second buffer using any or combination of a first/second pressure regulators and one or more first/second valves. A mixing chamber configured with the first buffer and the second buffer to receive and mix the first fluid and the second fluid. A delivery tank configured with the mixing tank to controllably receive the third fluid through one or more fourth valves and a third pressure regulator. A user feed mask having an inlet configured with the delivery tank and user's face facilitating breathing assistance to the user.

A ventilator includes a bidirectional breath detection airline and a flow outlet airline. The flow outlet airline includes an airline outlet. The flow outlet airline is configured to be connected to an invasive ventilator circuit or a noninvasive ventilator circuit. The breath detection airline includes airline inlet. The airline inlet is separated from the airline outlet of the flow outlet airline. The ventilator further includes a pressure sensor in direct fluid communication with the breath detection airline. The pressure sensor is configured to measure breathing pressure from the user and generate sensor data indicative of breathing by the user. The ventilator further includes a controller in electronic communication with the pressure sensor. The controller is programmed to detect the breathing by the user based on the sensor data received from the pressure sensor.

A system (1000) for a feeding of substances to a patient (30) with ventilation and oxygenation of the patient. The system (1000) includes a ventilation system (1), an oxygenation system (2), a breathing gas dispensing path (3), a purge gas dispensing path (4), a breathing gas connection system (5), an oxygenation connection system (6), a dispensing system (7), a switching unit (8), and at least one control unit (9). The switching unit (8) is configured for a distribution or splitting of a quantity of a drug or anesthetic active ingredient, which quantity was dispensed into a gas mixture by means of the dispensing system (7), between the ventilation system (1) and the oxygenation system (2). The at least one control unit (9) is configured to control the switching unit (8).

Methods and systems for increasing oxygen concentration. An example system includes an oxygen valve configured to be coupled to an oxygen source, an oxygen plenum coupled to the valve, and a mixing valve. The mixing valve includes an oxygen inlet coupled to the oxygen plenum, an ambient-air inlet, and an outlet configured to be attached to an inlet of a blower of a ventilator. The system also includes a pressure sensor, coupled to the oxygen plenum, and a control device communicatively coupled to the pressure sensor and the oxygen valve. The control device receives a differential pressure, measured by the pressure sensor, and based on the measured differential pressure, generates a control signal to control the oxygen valve to maintain a target pressure of gas within the oxygen plenum.

An insufflation system includes an insufflation device for supplying gas to a body cavity, and a suction device for suctioning the gas from the body cavity through a suction conduit at a suction flow rate. The insufflation device includes a flow rate sensor for measuring a gas feeding flow rate, a pressure sensor for measuring body cavity internal pressure, a first on-off valve for controlling the gas feeding flow rate, a second on-off valve for opening and closing the suction conduit, and a processor for opening the second on-off valve and controlling the first on-off valve to feed the gas at an amount when a first target gas feeding flow rate calculated from difference between the body cavity internal pressure and insufflation target pressure is lower than a threshold flow rate, the amount being obtained by adding the suction flow rate to the first target gas feeding flow rate.

An oxygen concentrator (100) apparatus and a method thereof implement operations control to efficiently release oxygen enriched gas to reduce potential waste. The control methodology may include generating a profile such as a minimum inhalation flow profile of the user. The profile may be based on a size parameter of the user. The method may determine one or more control parameters characterizing a bolus of oxygen enriched gas based on the generated flow profile. The control methodology may then generate a bolus release control signal, such as for a supply valve, according to the determined one or more control parameters. The oxygen concentrator may then, with the control signal, release and deliver a bolus of oxygen enriched gas for a user such as for reducing waste.

Systems and methods for nitric oxide (NO) generation systems are provided. In some embodiments, an NO generation system comprises at least one pair of electrodes configured to generate a product gas containing NO from a flow of a reactant gas. The electrodes have elongated surfaces such that a plasma produced is carried by the flow of the reactant gas and glides along the elongated surfaces from a first end towards a second end of the electrode pair. A controller is configured to regulate the amount of NO in the product gas by the at least one pair of electrodes using one or more parameters as an input to the controller. The one or more parameters include information from a plurality of sensors configured to collect information relating to at least one of the reactant gas, the product gas, and a medical gas into which the product gas flows.