Apparatus and methods for delivering humidified breathing gas to a patient are provided. The apparatus includes a humidification system configured to deliver humidified breathing gas to a patient. The humidification system includes a vapor transfer unit and a base unit. The vapor transfer unit includes a liquid passage, a breathing gas passage, and a vapor transfer device positioned to transfer vapor to the breathing gas passage from the liquid passage. The base unit includes a base unit that releasably engages the vapor transfer unit to enable reuse of the base unit and selective disposal of the vapor transfer unit. The liquid passage is not coupled to the base unit for liquid flow therebetween when the vapor transfer unit is received by the base unit.

The present invention relates to systems and methods for multi-frequency oscillatory ventilation (MFOV). The system uses a broadband flow waveform more suitable for the heterogeneous mechanics of the lung. The system provides more efficient gas exchange and enhanced lung recruitment at lower airway pressures.

An oxygen concentrator includes one or more adsorbent sieve beds operable to remove nitrogen from air to produce concentrated oxygen gas at respective outlets thereof, a product tank fluidly coupled to the respective outlets of the sieve bed(s), a compressor operable to pressurize ambient air, one or more sieve bed flow paths from the compressor to respective inlets of the sieve bed(s), a bypass flow path from the compressor to the product tank that bypasses the sieve bed(s), and a valve unit operable to selectively allow flow of pressurized ambient air from the compressor along the one or more sieve bed flow paths and along the bypass flow path in response to a control signal. The valve unit may be controlled in response to a command issued by a ventilator based on a calculated or estimated total flow of gas and entrained air or % FiO.sub.2 of a patient.

A ventilator system is presented. The ventilator system includes a controller configured to generate a first control signal for a first time-period and a second control signal for a second time-period during an inspiration time. Also, the ventilator system includes a rotary pump configured to change one of a pressure and a flow rate of the drive gas to a first value if the first control signal is received and change the one of the pressure and the flow rate of the drive gas to a second value if the second control signal is received. Further, the rotary pump is configured to deliver the drive gas to cause supply of a medical gas during the inspiration time, wherein the medical gas is supplied based on the one of the pressure and the flow rate of the drive gas delivered from the rotary pump.

Systems and methods for nitric oxide (NO) generation systems are provided. In some embodiments, an NO generation system comprises at least one pair of electrodes configured to generate a product gas containing NO from a flow of a reactant gas. The electrodes have elongated surfaces such that a plasma produced is carried by the flow of the reactant gas and glides along the elongated surfaces from a first end towards a second end of the electrode pair. A controller is configured to regulate the amount of NO in the product gas by the at least one pair of electrodes using one or more parameters as an input to the controller. The one or more parameters include information from a plurality of sensors configured to collect information relating to at least one of the reactant gas, the product gas, and a medical gas into which the product gas flows.

Architectures for production of nitric oxide (NO) include systems and methods for generating NO having one or more plasma chambers configured to ionize a reactant gas to generate a plasma for producing a product gas containing NO using a flow of the reactant gas through one or more plasma chambers; a controller configured to regulate the amount of nitric oxide in the product gas using one or more parameters as an input to the controller, one or more parameters including information from a plurality of sensors configured to collect information relating to at least one of the reactant gas, the product gas, and a medical gas into which product gas flows; and a flow divider configured to divide a product gas flow from the plasma chamber into a first product gas flow to provide a variable flow to a patient inspiratory flow and a second product gas flow.

A ventilator (100) configured to control a pressure and gas mixture for an air flow. The ventilator include: a gas source (220); a proportional valve (210) configured to control a gas flow rate from the gas source; a mix controller (170) in communication with the proportional valve, the mix controller configured to monitor a flow of gas through the blower, and further configured to control a percentage of oxygen in the output flow; a blower motor (160); and a blower motor controller (162) configured to control a speed of the blower motor using a current feedback loop, a blower speed feedback loop, a flow feedback loop, and a pressure feedback loop. The ventilator can also include, for example, a pseudo-derivative feedback compensator, a complimentary filter, and/or a speed controller.

An apparatus (1) for supplying a gas mixture to a patient, having a gas inlet line (30) with a gas inlet orifice (30a) that splits into a first gas line (31) and a second gas line (32); at least one permeation module (33) arranged on the second gas line (32), the said permeation module (33) having a feed port (33a) in fluidic communication with the second gas line (32), a retentate port (33b) and a permeate port (33c); a third gas line (34) in fluidic communication with the retentate port (33b) of the permeation module (33); a fourth gas line (35) in fluidic communication with the permeate port (33c) of the permeation module (33), and coupling fluidically to the said first gas line (31); and a source (360) of air in fluidic communication with the first gas line (31) and the fourth gas line (35).

An Automatic Supplemental Oxygen Control unit, a portable device that automatically monitors and adjusts the flow of supplemental oxygen to the subject in response to the oximetry and other readings derived from sensors attached to the subject and the oxygen source and provides programmed responses to physical inputs from such sensors to provide a closed loop oxygen delivery system.

Disclosed is a respirator which comprises an electronic control device and a pneumatic main line in which the following are connected pneumatically: a respiratory gas source, a valve, a mixing chamber, a gas-dosing unit, and a supply line. The gas-dosing unit is configured to convey external air and/or oxygen and/or anesthetic gas into the mixing chamber, the respiratory gas source is configured to deliver respiratory gas to the supply line, the mixing chamber is configured to make available respiratory gas, the supply line is configured to supply the patient with respiratory gas, and the valve is configured to at least temporarily reduce a stream of respiratory gas to a patient.