Example deflectable catheter systems are described. An example deflectable catheter system includes a housing, an orienting member, an actuator, a first elongate member, a second elongate member, and a wire member. The housing defines a passageway. The orienting member is attached to the housing. The actuator is attached to the orienting member and is moveable between an actuator first position and an actuator second position. The first elongate member is attached to the orienting member and defines a lumen. The first elongate member is moveable between a first, substantially straight configuration when the actuator is in the actuator first position and a second, curved configuration when the actuator is in the actuator second position. The second elongate member is disposed through the passageway of the housing and extends through the lumen defined by the first elongate member. The second elongate member is rotatable relative to the first elongate member.

A method for delivering an immunotherapy agent to a tumor includes advancing the delivery device into a vessel of a patient, and infusing the agent under pressure into the vessel to penetrate the tumor. The delivery device prevents reflux of the agent toward non-treatment sites.

Among other things, there is disclosed structure and methods for maintaining access to a location in the body while reducing or eliminating the potential for pulling an access device (e.g. a catheter) back through an opening. An introducer sheath includes a distal indented portion and a balloon, so that once placed in a desired location through tissue, the balloon can be inflated to anchor the sheath against retraction. In particular embodiments, structure and methods for accessing the pericardial cavity via the right atrial appendage are shown.

Cut-pattern designs creating a frame structure from a solid tube, which may be used as a portion of medical device, such as a catheter. The tube includes a plurality of units of cutout segments which are distributed in band around a circumference of the tube. A tube can have multiple different zones, each having units with varying cutout segments. The cutout segments can have varying cutout surface area allowing the flexibility of the tube to be modified at any point along the tube by altering the cutout surface area with zones having greater cutout surface areas as compared to another zone are more flexible. The tube can be incorporated into a catheter.

A steerable catheter has a body with an outer surface and an inner surface defining a central lumen. The outer surface and inner surface define a wall of the body, which has a plurality of steering lumen and control lumen extending longitudinally therethrough. The body includes a body material. The steering lumen and control lumen have a control lumen lining and steering lumen lining, respectively, with a higher durometer than the body material. A steering wire is positioned within the steering lumen and a control wire is positioned within the control lumen.

An embolization microcatheter is configured to deliver embolization particles to a target area and minimize or prevent embolization of a non-target area. The microcatheter includes a section, located between the distal and proximal ends of the microcatheter, having a skeleton formed of braided wires and a polymeric layer intercalated into and/or overlaying the skeleton. This section includes a plurality of axial slits, each slit having a smallest cross-sectional dimension configured to prevent outflow of the embolization particles.

The present disclosure relates to catheter system comprising a balloon and an infusion basket designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a drug delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis and thrombectomy.

A steerable catheter has a body with an outer surface and an inner surface defining a central lumen. The outer surface and inner surface define a wall of the body, which has a plurality of steering lumen and control lumen extending longitudinally therethrough. The body includes a body material. The steering lumen and control lumen have a control lumen lining and steering lumen lining, respectively, with a higher durometer than the body material. A steering wire is positioned within the steering lumen and a control wire is positioned within the control lumen.

In examples, a microcatheter includes an enhanced inner liner that has a low coefficient of friction and improved toughness, which facilitates delivery of expandable vascular reconstruction devices. The microcatheter may include a stretched polytetrafluoroethylene (PTFE) liner, which may be stretched longitudinally and not circumferentially or radially over at least a portion of a length of the microcatheter. The stretched PTFE inner liner may result in the reduction of a delivery friction and improved toughness and resistance to scraping.

An intravascular device delivery system includes an elongated member with a proximal end, a distal end, and a longitudinal axis therebetween. The elongated member includes a multilumen catheter having a catheter wall with a plurality of lumen in the catheter wall. The plurality of lumen extends from a proximal end of the elongated member to a distal end of the elongated member. A lumen ratio of the cross-sectional area of the plurality of lumen and the cross sectional area of the catheter wall is greater than 30%.