Systems and methods for deriving pressures outside of a blood inlets and blood outlets of an intracardiac blood pump assembly, and pressure differentials therebetween. Pressures outside of a blood inlet may be derived based on one or more readings from a pressure sensor placed within a blood inlet, one or more readings from a differential pressure sensor configured to measure pressure differential across a wall of the pump housing or cannula, and speed of the pump motor. Pressure differentials between a blood inlet and blood outlet may be derived based on one or more readings from the differential pressure sensor and speed of the pump motor. Pressures outside of a blood outlet may be derived based on a derived pressure outside of a blood inlet and a derived pressure differential between the blood inlet and the blood outlet.

Systems and methods for deriving pressures outside of a blood inlets and blood outlets of an intracardiac blood pump assembly, and pressure differentials therebetween. Pressures outside of a blood inlet may be derived based on one or more readings from a pressure sensor placed within a blood inlet, one or more readings from a differential pressure sensor configured to measure pressure differential across a wall of the pump housing or cannula, and speed of the pump motor. Pressure differentials between a blood inlet and blood outlet may be derived based on one or more readings from the differential pressure sensor and speed of the pump motor. Pressures outside of a blood outlet may be derived based on a derived pressure outside of a blood inlet and a derived pressure differential between the blood inlet and the blood outlet.

Systems and methods for managing heart failure are described. The system receives physiological information including a first HS signal corresponding to paced ventricular contractions and a second HS signal corresponding to intrinsic ventricular contractions. The system detects worsening heart failure (WHF) using the received physiological information. A signal analyzer circuit can generate a paced HS metric from the first HS signal and a sensed HS metric from the second HS signal, and determine a concordance indicator between the paced and the sensed HS metrics. In response to the detected WHF, the system can use the concordance indicator to generate a therapy adjustment indicator for adjusting electrostimulation therapy, or a worsening cardiac contractility indicator indicating the detected WHF is attributed to degrading myocardial contractility.

A vascular coupling device for connecting an artificial heart pump to the vascular system of a subject is disclosed. The artificial heart pump may form part of a total artificial heart (TAH). The vascular coupling device comprises a first and a second coupling element, each one of said first and second coupling elements has a first end comprising a resilient coupling portion, a second end comprising a vascular grafting material, and a tubular midsection is arranged between said first and second ends. The vascular coupling device further comprises a coupling plate comprising a first receptor and a second receptor configured and adapted for receiving said resilient coupling portions of the first and second coupling elements. The vascular coupling device further comprises a docking plate, comprising a first and a second docking port configured to be arranged to an inlet channel and an outlet channel of said artificial heart pump and one or more fastening means for connecting said coupling plate to the docking plate. A method for connecting the vascular coupling device to the vascular system of a subject is also disclosed.

A vascular coupling device for connecting an artificial heart pump to the vascular system of a subject is disclosed. The artificial heart pump may form part of a total artificial heart (TAH). The vascular coupling device comprises a first and a second coupling element, each one of said first and second coupling elements has a first end comprising a resilient coupling portion, a second end comprising a vascular grafting material, and a tubular midsection is arranged between said first and second ends. The vascular coupling device further comprises a coupling plate comprising a first receptor and a second receptor configured and adapted for receiving said resilient coupling portions of the first and second coupling elements. The vascular coupling device further comprises a docking plate, comprising a first and a second docking port configured to be arranged to an inlet channel and an outlet channel of said artificial heart pump and one or more fastening means for connecting said coupling plate to the docking plate. A method for connecting the vascular coupling device to the vascular system of a subject is also disclosed.

The present invention provides an intravascular blood pump comprising an impeller housing and/or impeller blade(s) that may be expandable and collapsible. The blade(s) and/or impeller housing may be biased to expand or may be expanded by centrifugal forces generated during rotation of the impeller and blades with an operatively connected rotational motor.

The present invention provides an intravascular blood pump comprising an impeller housing and/or impeller blade(s) that may be expandable and collapsible. The blade(s) and/or impeller housing may be biased to expand or may be expanded by centrifugal forces generated during rotation of the impeller and blades with an operatively connected rotational motor.

An inflow cannula for an implantable blood pump, the inflow cannula defining an inlet at a proximal end, an opposite distal end, and a lumen therebetween, the inflow cannula being configured to constrict the lumen.

An inflow cannula for an implantable blood pump, the inflow cannula defining an inlet at a proximal end, an opposite distal end, and a lumen therebetween, the inflow cannula being configured to constrict the lumen.

The invention relates generally to wearable accessory carriers for mechanical circulatory support systems, and more specifically relates to belts for carrying peripheral components of a VAD. Such wearable accessory carriers may be suitable for carrying and retaining peripheral components of the VAD in a safe, comfortable, and convenient manner. In certain aspects, the invention provides a wearable accessory carrier configured as an elastic belt with several pockets for holding peripheral components. In other aspects, a wearable accessory carrier may be configured as a belt with a magnetic strip configured to carry one or more modular compartments or pockets for holding peripheral components via magnetic attachment. The wearable accessory carriers disclosed herein may be sized to fit around or configured to be worn on a patient's waist, lower or upper torso, thigh, calf, arm, or other limb.