The invention comprises an apparatus and a method for aiding function of a heart, comprising the steps of: (1) sensing a pulse; (2) providing a blood flow assist device, comprising: a first electroactive polymer sleeve segment circumferentially positioned about a portion of a first body part and a second electroactive polymer sleeve segment circumferentially positioned about a segment of a second body part; (3) sequentially constricting, timed to the pulse, the first electroactive polymer sleeve segment and the second electroactive polymer sleeve segment to aid the heart in circulation of blood; and (4) repeating the step of sensing the pulse and the step of constricting.

A spring (3, 3) comprising a plurality of elements (30), each element (3) comprising a rigid portion (31) and a flexible beam (32), the extremities (320, 321) of the flexible beam being supported by the rigid portion (31), the flexible beam (32) having a single stable position, so that the flexible beam can be deformed when a pressure is exerted between said extremities in the direction of the rigid portion (31), and returns to said single stable position when the pressure is released, and wherein the rigid portion (31) of at least one element (30) is in contact with the flexible beam (32) of the next element between said extremities (320, 321) of the flexible beam (32), so that the spring has a negative stiffness over an operating range. The arrangement ensures a pure radial compression/expansion of the spring.

A spring (3, 3) comprising a plurality of elements (30), each element (3) comprising a rigid portion (31) and a flexible beam (32), the extremities (320, 321) of the flexible beam being supported by the rigid portion (31), the flexible beam (32) having a single stable position, so that the flexible beam can be deformed when a pressure is exerted between said extremities in the direction of the rigid portion (31), and returns to said single stable position when the pressure is released, and wherein the rigid portion (31) of at least one element (30) is in contact with the flexible beam (32) of the next element between said extremities (320, 321) of the flexible beam (32), so that the spring has a negative stiffness over an operating range. The arrangement ensures a pure radial compression/expansion of the spring.

A system configured to be at least partially implanted along an aorta includes an inelastic, static member and a pinching member. The pinching member is configured to receive an activation signal at an activation rate and in response to the activation signal, repeatedly compress the aorta at the second location at the activation rate to pump fluid within the aorta in a desired pumping direction. The system is configured to selectively control wave reflections in order to achieve both improved wave dynamics to reduce cardiac load and increased (or at least non-diminished) blood flow to targeted organs within the cardiovascular system.

An actuation system includes a virtual or computer-modeled portion that is coupled to a physical portion. The virtual portion is a computer model that models or otherwise simulates a function or action, such as a physiological function or action, including for example an action potential, a calcium transient, and/or a chemical reaction. The computer model may model or simulate a chemical action, a mechanical action (such as movement of a wing) or any other action. The virtual portion drives or controls one or more physical actuators, which can be sized on a microscopic scale, such as on a nanometer scale. The actuation system can be used as or part of an artificial anatomical structure or organ, such as an artificial heart.

Circulatory assistance device for a heart of a living being, including a cuff for periodically applying pressure to the heart by at least one dielectric elastomer membrane which is controllable by a control device in synchronization with a cardiac beat in order to convey blood in pulses, wherein the cuff is designed to be pulled over the outside of the heart and for this purpose has an inner shape that is adapted to the outer contour of the heart at least in the region outside the ventricles, wherein the cuff is composed of an outer contraction layer including the dielectric elastomer membrane and an inner padding layer, and the padding layer is filled with an incompressible liquid and has at least one outlet valve, which is closed in a normal state and opened in an emergency state.

A system configured to be at least partially implanted along an aorta includes an inelastic, static member and a pinching member. The pinching member is configured to receive an activation signal at an activation rate and in response to the activation signal, repeatedly compress the aorta at the second location at the activation rate to pump fluid within the aorta in a desired pumping direction. The system is configured to selectively control wave reflections in order to achieve both improved wave dynamics to reduce cardiac load and increased (or at least non-diminished) blood flow to targeted organs within the cardiovascular system.

Methods and apparatuses relate to an implantable device for providing contractile assistance to an organ. The device may include an actuator and anchors located on either side of the actuator. The anchors engage with oppositely positioned tissue walls of an organ chamber, and provide contractile assistance to the organ, repeatedly, at appropriate times. For example, the device may be implanted within the right ventricle, anchored to the right ventricular free wall and the ventricular septum. The device may function to bring the opposing walls of the ventricle toward one another, synchronized with the pacing of the heart, resulting in an improved ejection fraction of blood from the chamber. In some embodiments, the actuator includes a bladder that is configured to contract upon receiving an inflow of pressurized fluid therein. When the fluid exits therefrom, the bladder relaxes back to an initial, extended state.

The invention relates to actuators based on electroactive polymeric materials for use in pumping fluids or in other applications where a contractile actuation is required, in particular, although not necessarily exclusively, for use in vascular pulsation devices such as a variable aortic tension device. Embodiments disclosed include an actuator comprising: an inner tubular structure; an outer tubular structure surrounding the inner tubular structure and comprising a plurality of layers of a dielectric elastomeric material and a tubular elastic support structure, the elastic support structure configured to maintain a pre-stress in the layers of the dielectric elastomeric material, wherein the outer tubular structure is configured to contract in a radial direction around the inner tubular structure upon application of an actuation voltage signal across the dielectric elastomeric material layers.

Methods and apparatuses relate to an implantable device for providing contractile assistance to an organ. The device may include an actuator and anchors located on either side of the actuator. The anchors engage with oppositely positioned tissue walls of an organ chamber, and provide contractile assistance to the organ, repeatedly, at appropriate times. For example, the device may be implanted within the right ventricle, anchored to the right ventricular free wall and the ventricular septum. The device may function to bring the opposing walls of the ventricle toward one another, synchronized with the pacing of the heart, resulting in an improved ejection fraction of blood from the chamber. In some embodiments, the actuator includes a bladder that is configured to contract upon receiving an inflow of pressurized fluid therein. When the fluid exits therefrom, the bladder relaxes back to an initial, extended state.