A pre-filled syringe having containing therein at least one therapeutic is provided. The syringe contains a silicone free barrel and an elastomeric syringe stopper that is covered with an expanded polytetrafluoroethylene barrier layer. The presence of a barrier layer that is at least partially porous on the outside of the syringe stopper improves the seal between the stopper and syringe barrel and minimizes the sliding force. In some embodiments, the barrel is formed of a glass material such as a borosilicate glass, that is free of silicone or other lubricants.

Coated pharmaceutical packages are disclosed. In embodiments, a coated pharmaceutical package may include a glass body comprising a first surface. A low-friction coating may be positioned on at least a portion of the first surface of the glass body. The low-friction coating may include a polymer chemical composition. The coated pharmaceutical package may be thermally stable at a temperature of at least about 260 C. for 30 minutes. The low-friction coating may have a mass loss of less than about 5% of its mass when heated from a temperature of 150 C. to 350 C. at a ramp rate of about 10 C./minute.

The disclosure provides a core layer for an information carrying card, resulting information carrying card, and methods of making the same. A core layer for an information carrying card comprises at least one thermoplastic layer having at least one cavity, an inlay layer, and, and a crosslinked polymer composition. At least one portion of the inlayer layer is disposed inside the at least one cavity of the at least one thermoplastic layer. The crosslinked polymer composition is disposed over the at least one thermoplastic layer and contacting the inlayer layer.

A single use bag for storing a material. The single use bag includes a two layers of which one of the two layers is in contact with the material container within the bag. The layer which is in contact with the material contained within the bag is an active layer. The active layer may be made active by incorporating a scavenger into the layer. At least one layer of the single use bag may include a fluoropolymer.

As described herein, a polyimide chemical composition may be used for coating glass articles. According to embodiments, a coated glass article may include a glass container which may include a first surface and a second surface opposite the first surface, and a low-friction coating bonded to at least a portion of the first surface of the glass container. The low-friction coating may include a polyimide chemical composition. The polyimide chemical composition may be halogenated and the polyimide chemical composition may include a siloxane moiety.

Glass pharmaceutical packages with coatings are disclosed herein. According to one embodiment, the glass pharmaceutical package includes a glass body enclosing an inner volume and having an exterior surface. A coating may be positioned on at least a portion of the exterior surface of the glass body. The coating may include a coupling agent layer having a first thickness of greater than or equal to 25 nm and less than or equal to 100 nm. A polymer layer having a second thickness of less than 50 nm may be positioned over the coupling agent layer.

A container having a barrier layer is provided. The container may be of thermoplastic and the barrier may inhibit materials from leaching from the thermoplastic material or from extraction of compounds from medicants by the thermoplastic. A process is also described that allows for molding thin barrier layers as container lines and for forming thermoplastic containers with barrier liners.

The disclosure provides a core layer for an information carrying card, resulting information carrying card, and methods of making the same. A core layer for an information carrying card comprises at least one thermoplastic layer having at least one cavity, an inlay layer, and, and a crosslinked polymer composition. At least one portion of the inlayer layer is disposed inside the at least one cavity of the at least one thermoplastic layer. The crosslinked polymer composition is disposed over the at least one thermoplastic layer and contacting the inlayer layer.

A coated glass pharmaceutical package may include a body formed from a Type 1 Class glass according to ASTM Standard E438-92. The body may have an interior surface and an exterior surface. The body may also have at least a class A2 base resistance or better according to ISO 695, at least a type HGB2 hydrolytic resistance or better according to ISO 719 and a Type 1 chemical durability according to USP <660>. A coating having a thickness of 100 microns may be positioned on at least a portion of the exterior surface. The portion of the exterior surface with the coating may have a coefficient of friction that is at least 20% less than an uncoated glass pharmaceutical package and the coefficient of friction does not increase by more than 30% after undergoing a depyrogenation.

Provided are a coating composition for forming a gas barrier layer as configured such that a specific compound having two or more 5-membered cyclic carbonate groups and a compound having two or more amino groups are reactable at an equivalent ratio of functional groups of 0.8 to 1.25 to form the gas barrier layer with a polyhydroxyurethane resin as a principal component; a gas barrier film formed of a single layer or multiple layers, at least one of the layer or layers that forms or form the film is a layer that exhibits gas barrier properties, and the layer is formed of a polyhydroxyurethane resin having a specific chemical structure; and a production method of a film having gas barrier properties. Owing to the use of the specific polyhydroxyurethane resin, the coating composition, gas barrier film and production method readily enable to reduce moisture-dependent variations in gas barrier properties, to avoid the production of noxious fumes upon incineration disposal, to provide excellent processability, and to lower the pollutant load on the environment.