A method for processing biological material containing stringy tissue in a container having a tissue collector disposed in a tissue retention volume on one side of an internal filter includes washing biological material contained in the tissue retention volume with wash liquid to the tissue retention volume and allowing the wash liquid and rotating the tissue collector disposed in the tissue retention volume relative to the container in a first direction of rotation about an axis of rotation to sweep the teeth positioned on the tissue collector through the biological material and to collect stringy material on the tissue collector.

Cells present in processed lipoaspirate tissue are used to treat patients, including patients with renal conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic renal benefit.

The present invention relates to a component separator capable of guaranteeing the purity of a subject component such as isolated blood or stem cells while simplifying a process compared with a conventional technique, and preventing air contamination during a component separation process, the component separator comprising: a hollow main body having a communication pipe, through which a body fluid communicates, formed at one end portion, and a main body female screw part disposed at the other end portion; a plunger for varying a main body space while moving forward and backward inside the main body; and an operation member having a pressing tube having a pressing male screw part capable of being screwed with the main body female screw part, and a plunger coupling tube having a tube screw screwed with a plunger screw part at the lower part of the plunger by coming into contact with or retracting from the inside of the pressing tube.

Certain embodiments are directed to compositions and methods for non-cytotoxic hematopoietic stem cell transplantation.

The present disclosure relates to methods and apparatus for producing platelet rich plasma, bone marrow mononuclear cells, stromal vascular fraction from adipose tissue, and other concentrated or enriched biological fluids.

A system and method to deliver a medicant to a premature fetus in an extracorporeal environment. Exemplary medicants include at least one selected from stem cells and modified genes. The system can include a chamber to enclose the fetus, a first fluid circuit including a source of a liquid, a pump configured to move the liquid, and a second fluid circuit including an oxygenator configured to transfer oxygen to the fetus. The umbilical cord of the fetus is connected to the second fluid circuit by attaching a first cannula connected to a vein of the umbilical cord, attaching a second cannula to a first artery of the umbilical cord, attaching a third cannula to a second artery of the umbilical cord, and connecting one or more of the first, second and third cannulae to the oxygenator via an oxygenation circuit.

A method for processing biological material containing stringy tissue in a container having a tissue collector disposed in a tissue retention volume on one side of an internal filter includes washing biological material contained in the tissue retention volume with wash liquid to the tissue retention volume and allowing the wash liquid and rotating the tissue collector disposed in the tissue retention volume relative to the container in a first direction of rotation about an axis of rotation to sweep the teeth positioned on the tissue collector through the biological material and to collect stringy material on the tissue collector.