Devices and methods are provided for use in the treatment of bladder cancer by locally administering oxaliplatin into the bladder of a patient to achieve a sustained concentration of oxaliplatin in urine in the bladder sufficient to produce a therapeutic concentration of oxaliplatin in bladder tissue. The oxaliplatin may be delivered into the bladder from an intravesical drug delivery device inserted into the bladder, wherein the device continuously releases the oxaliplatin into the urine in the bladder over an extended period of hours or days.

An insertion aid for catheter manipulation is disclosed. The insertion aid can be used for urinary catheters, such as hydrophilic urinary catheters for intermittent use. The insertion aid includes first and second plate-like arms arranged overlying each other and with a separation distance there between. The insertion aid also includes a resilient hinge connecting adjacent marginal edges of the plate-like arms together. At least one of the plate-like arms includes a groove on its clamping inner surface for holding a catheter shaft. The groove extends at least partly in the same direction as, and essentially parallel to, the resilient hinge, and is arranged at a distance both from the resilient hinge and from the marginal edge of the plate-like arm. Corresponding catheter set and catheter assembly are also disclosed.

A dilating device for the prostatic urethra comprising: Prostatic implant includes independently actuatable distal retractor incorporating and proximal retractor. Retractors may be connected via a spine member. System and method include implant manipulator detachably connected to implant, for manipulating and forcing implant into close proximity, for delivery into subject.

Catheter-adapted briefs operative to stabilize an indwelling urethra catheter in a position of alignment with the natural orientation of the male urethral orifice to minimize catheter discomfort, prevent urine leakage, tissue damage, and reduce the frequency of urinary track infection.

A negative pressure therapy system is provided for inducing negative pressure in a portion of a urinary tract of a patient, the system including: (a) at least one ureteral catheter configured to be positioned within a ureter and/or kidney of a patient; (b) one or more sensor(s) configured to determine information about urine produced within a urinary tract of the patient; and (c) a controller configured to increase urine production of the patient by adjusting one or more operating parameters of a negative pressure source for inducing negative pressure through the at least one ureteral catheter into the urinary tract of the patient, based at least in part upon the information determined by the one or more sensor(s).

A device for insertion of material into a urethra comprising: a nozzle with a rounded nozzle tip, sized for at least partial insertion into the urethra; and a source of compressed material coupled to the nozzle where a pressure of the compressed material is less than 200 cm H.sub.2O; a control, for control of flow of material from the source through the nozzle; wherein a maximum extent of the device is less than 30 cm.

A catheter assembly (10) comprising: a hydrophilic urinary catheter (16) having a catheter shaft including a proximal insertion end portion (22) and a distal end portion (24) having a drainage member (26), a collapsible sleeve (12) defining a compartment (14) that contains a portion of the catheter shaft, a distal end portion (32) of the sleeve (12) being attached to the distal end portion (24) of the urinary catheter (16); an amount of liquid (20) located within the compartment (14); an introducer (28) located at a proximal end portion (30) of the sleeve (12), the introducer (28) including a passageway therethrough and a proximal opening for passage of the catheter shaft therethrough; and a removable cap (46) covering the introducer (28) wherein the cap (46) includes an anti-leak element.

A system suitable for collecting and transporting urine away from the body of a person or animal may include an assembly having a fluid impermeable casing, a fluid permeable membrane, and a fluid permeable support. A reservoir is defined by the fluid permeable support. The fluid permeable membrane can define a cavity. The casing can define an opening such that the cavity is accessible via the opening. The assembly can also include an outlet in fluidic communication with the reservoir. The assembly can be arranged such that a user's penis can be disposed through the opening with the urethral opening disposed within the cavity and such that a fluid can flow into the body from the urethral opening of the user's penis, collect in the reservoir, and flow out of the outlet.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.