An electroporation device having a battery pack including a plurality of battery cells and at least one lead in electrical communication with a circuit board. The battery pack including a safety switch and a controller for selectively placing the battery cells in electrical communication with the one lead. Where the controller is in operable communication with the safety switch such that when the controller detects one or more operating conditions the controller instructs the safety switch to electrically isolate the lead from the battery cells. The battery pack also includes a manual switch, and where activation of the switch causes the controller to instruct the safety switch to electrically isolate the lead from the battery cells.

Nano-patterned devices for triggered intracellular delivery of active materials are disclosed. The device may comprise a nano-sized polyelectrolyte multilayer (PEM) comprising at least one layer of an electroactive polyelectrolyte polymer, where the PEM is configured to hold or receive an active material to be disposed within the multilayer and to release the active material under an electric field.

A skin care device according to an embodiment includes a main body and a head part connected to the main body, wherein the head part includes a housing in which an upper portion thereof is open, and including an accommodation space therein, an electrode part disposed in the housing, a plurality of light emitting elements disposed in the housing and spaced apart from the electrode part, and a cover part for shielding of the open upper region of the housing, wherein the cover part includes a hole corresponding to the electrode part, a part of the electrode part protrudes from an upper surface of the cover part via the hole, and an upper surface of the electrode part facing a skin of a user includes a convex curved surface toward the skin.

There is disclosed systems and methods for non-invasive delivery of an agent to biological tissues. Delivery of the agent to the tissues can be by one or more modalities. In some embodiments the systems and methods use agent carrier body including a tissue contacting surface for non-invasively engaging tissues under treatment. The tissue contacting surface can be at least partly defined by a plurality of protrusions that are in fluid communication with one or more reservoirs forming part of the agent carrier body. The protrusions may extend outward from an inside of a void and terminate at said tissue contacting surface.

An adaptive transdermal iontophoretic introduction system for the beauty field is provided. Specifically, the system includes an iontophoretic introduction system, and a control and drive electronic system. The control and drive electronic system includes an operation system, a central processing system, an electrode drive system, a sensing system and a data communication system. The adaptive transdermal iontophoretic introduction system provides personalized transdermal drug delivery according to the actual condition of a user's skin, optimizes the dose, depth and speed of the transdermal drug delivery in real time, and maximizes the product usage effect and safety.

A method and apparatus to treat hyperhidrosis is provided in which a battery provides a milliampere electrical current to the inside of a waterproof glove containing water and sealed to the user's arm so that circulation is not unduly restricted while the user can raise the water-filled gloves and hands above the user's head without leaking. A tapered portion on the proximal end of each glove is folded inside the glove to seal against the user's arm to form a pocket between the tapered portion which seals against the user's arms, and part of a wrist portion of the glove located radially outward of the tapered portion. When the user's gloves and hands rotate upward, water collects in the pocket(s) while the tapered portion provides a leakproof seal, thus allowing manual manipulation while wearing the water-filled gloves.

A transdermal delivery system (1) configured to deliver an active agent to human or animal tissue, comprising a penetrative electrode (2) of one polarity that provides an electrical contact (3) beneath the stratum corneum (20); a surface electrode (4) of the opposite polarisation to that of the penetrative electrode (2) that provides an electrical contact to the external surface of the skin (21) on the opposite side of the stratum corneum (20) to the electrical contact (3) of the penetrative electrode (2); a dispenser (5) configured to deliver of an active agent to the external surface of the skin (21) adjacent to an electrical contact of the surface electrode (4); a method of delivering the active agent to the tissue of a human or animal body using the transdermal delivery system (1) and an electrode assembly (10) for use in preparing the transdermal delivery system (1).

In one aspect, the disclosure relates to drug delivery devices for the ionophoretic delivery of a therapeutic agent(s) to the eye. In some aspects, the disclosed ionophoretic ocular delivery device is configured for delivery of a therapeutic agent to the anterior portion of the eye. In various aspects, the present disclosure provides methods for treatment of an ophthalmological disorder, disease, or clinical condition by delivering a therapeutic agent(s) to the eye using a disclosed ionophoretic ocular delivery device. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

A device for the cosmetic treatment of keratin materials with an electric current, including: a current generator (1), a reservoir (3) containing a cosmetic composition (P), an end piece (2) comprising an electrode (4) and at least one applicator member (6, 7), said applicator member (6, 7) delimiting an outer wall (61, 71) that is able to be filled with product contained in the reservoir (3), a counter electrode (5), a system for regulating the quantity of composition (P) exiting the reservoir (3) on the basis of the impedance measured between the electrode (4) and the keratin materials, the electrode (4) and the applicator member (6, 7) being designed such that the composition (P) is the only conductive substance in contact with the skin while the device is being used.

A system and method for the safe delivery of treatment energy to a patient, which includes verification of system integrity before, during, or after the delivery of treatment energy and provides several mechanisms for rapid termination of the delivery of potentially harmful energy to the patient when a fault condition in the device and/or system is identified. The system may include an energy generator having processing circuitry to determine if there is a fault condition in the system and to automatically terminate a delivery of treatment energy when the processing circuitry determines there is a fault condition. The method may generally include performing a series of pre-checks, synchronizing a treatment energy delivery to the proper segment of the heart's depolarization pattern, configuring the system for treatment energy delivery, delivering the treatment energy, and performing post-treatment evaluation.