A therapeutic intubation device may comprise a tube, a first probe channel, a second probe channel, a first probe and a second probe. In various embodiments, a tube may have an elongate body having a proximal end and a distal end. The body may define a first channel between the proximal end and the distal end. A first probe channel may be defined in the body. A second probe channel defined in the body. A first probe may comprise a first body portion and a first end portion, the first end portion comprising a first ultraviolet-c (“UVC”) light emitting device. The first probe may be installable the first probe channel such that the first end portion of the first probe is adjacent the distal end of the tub during operation.

A process for heat treating biological tissue includes providing a plurality of energy emitters formed into an array. Treatment energy in the form of ultrasound energy is generated from the plurality of emitters and applied to target tissue. The treatment energy has energy and application parameters selected so as to raise the target tissue temperature sufficiently to create a therapeutic effect while maintaining an average temperature of the target tissue over several minutes at or below a predetermined temperature so as not to destroy or permanently damage the target tissue.

A retinal phototherapy or photostimulation system includes a laser console generating at least one treatment beam having parameters to photostimulate or treat, while not permanently damaging, a retinal target tissue. The parameters of the at least one treatment beam are fixed so as not to be alterable by a medical provider. A projector or camera projects the at least one treatment beam onto at least a portion of the retina, and a scanning mechanism controllably directs the at least one treatment beam to treatment areas of the retina.

Treatment of respiratory viral infections including coronavirus using photosensitizers. A photoactivatable phenothiazine derivative, preferably a photoactivatable phenothiazine dye such as methylene blue, new methylene blue, toluidine blue and mixtures thereof is administered to the naso-pharyngeal tract of a subject, and is then activated with a light source.

A light-emitting, antimicrobial tuber, instrument or catheter includes a thin, flexible tube having an optically transparent wall; and a light transmitter configured and arranged to emit light through the tube, which may be ultraviolet C (UVC) irradiation, photodynamic therapy (PDT), violet-blue light therapy, and other light-based therapies. In one embodiment, violet-blue light from 400-500 nm in wavelength, such as 405 nm, for instance, is used. The device is used on a patient and a therapeutic amount of light is administered to the patient, thereby reducing the risk of infections being transmitted from the instrument, tube or catheter to the patient, generally. The device may be configured for use in the urinary tract or as intravascular, and may be indwelling or temporary. Light may be administered for the duration of use or another time period effective to halt, inhibit, or reduce microbial or fungal growth.

Systems and methods are provided for treating or preventing carbon monoxide poisoning. In particular, systems and methods are provided for a phototherapy treatment or prevention system that delivers light radiation to a patient's body to photodissociate carbon monoxide from hemoglobin.

A system may comprise a liquid source from which a liquid is delivered, and a catheter coupled to the liquid source. The catheter may include a distal portion from which the liquid is released into an anatomic lumen. The system may also include an occlusion device coupled to the catheter and configured to prevent flow of the liquid in the anatomic lumen proximally of the occlusion device. The system may also include a heating device near the distal portion of the catheter. The heating device may be configured to heat the liquid to a temperature of less than a vaporization temperature for the liquid.

A system for treating target tissue located at a first location along an anatomic lumen comprises a catheter including a distal end portion configured for deployment in the anatomic lumen. The system also comprises an expansion device coupled to the distal end portion of the catheter. The expansion device has an expanded size in a deployed configuration. The expansion device in the deployed configuration occludes the anatomic lumen at a second location, different from the first location, along the anatomic lumen. The expansion device also occludes at least one of a plurality of blood vessels adjacent the anatomic lumen to reduce blood flow to the target tissue at the first location.

A light emitting device is disclosed for intracorporeal Photobiomodulation (photostimulation, low-level light therapy, low-level laser therapy, phototherapy, photobiostimulation). The device will be removably inserted via a natural or surgically created orifice. The device will deliver therapeutic doses of electromagnetic radiation (EMR) light energy (photons) to cells, tissues, organs or body systems. The purpose of the device is to deliver light energy to cause a photochemical reaction for improving functionality, restoring functionality or causing a healing effect as needed for treating diseases, conditions or disorders of the body.

A far ultraviolet light application device for killing pathogens on tissue and proximate thereto includes a tube that is to be utilized in a medical procedure. A first fiberoptic cable is engaged to a wall of the tube so that a first end of the first fiberoptic cable is positioned proximate to a first terminus of the tube. The first fiberoptic cable has a second end operationally engaged an ultraviolet C light emitter so that ultraviolet C light is emitted proximate to the first terminus of the tube. The first fiberoptic cable directs the ultraviolet C light from the ultraviolet C light emitter so that the ultraviolet C light impinges upon tissue and pathogens proximate to the first terminus of the tube to inactivate the pathogens.