Mitochondrial antiviral signaling (MA VS) protein mediates innate antiviral responses, and is an important component of the response to severe acute respiratory syndrome coronavirus-2 (SARS-COV-2). Herein methods are provided to increase expression of mitochondrial antiviral signaling (MAVS) protein in epithelial cells by use of a UVA therapy to expose the epithelial cells to the UVA therapy, or to contact a first set of epithelial cells with a second set of epithelial cells which have been exposed to the UVA therapy, or to contact a first set of epithelial cells with the cell lysates of the second set of epithelial cells that have been exposed to the UVA therapy.

A process for preventing or treating myopia includes applying a pulsed energy, such as a pulsed laser beam, to tissue of an eye having myopia or a risk of having myopia. The source of pulsed energy has energy parameters including wavelength or frequency, duty cycle and pulse train duration, which are selected so as to raise an eye tissue temperature up to eleven degrees Celsius to achieve therapeutic or prophylactic effect, such as stimulating heat shock protein activation in the eye tissue. The average temperature rise of the eye tissue over several minutes is maintained at or below a predetermined level so as not to permanently damage the eye tissue.

The present invention relates to an endoscope (2) having first conduction means configured to transmit electromagnetic waves between an illumination device (40) for illuminating an observation area (41) and a distal end (5) of the endoscope (2), and second conduction means configured to transmit electromagnetic waves between a therapy device (42) for treating a therapy area (43) within the observation area (41) and the distal end (5) of the endoscope (82). The endoscope is characterized by a third conduction means configured to transmit electromagnetic waves between an optical coherence tomography device (37) by means of which depth information about said area can be obtained during treatment of the therapy area (43) and the distal end (5) of the endoscope (2).

The present invention provides a synthetic treatment apparatus which comprises: a connection part in which treatment part modules are replaced and are connected to or separated from each other, the treatment part modules performing inhalation, suction, light emitting, and aerosol functions, respectively, which are required for treatment for a respiratory disease and ear disease; a power part for supplying power to the treatment part modules according to an operation of a power switch; and a control part for controlling the power module and functions of the treatment part modules, wherein a grip part is formed on the outside of a body in which the power part and the control part are embedded. The present invention can treat various ear and respiratory diseases by replacing a head of the apparatus.

A process for heat treating biological tissue includes providing a plurality of energy emitters formed into an array. Treatment energy is generated from the plurality of emitters and applied to target tissue. The treatment energy has energy and application parameters selected so as to raise the target tissue temperature sufficiently to create a therapeutic effect while maintaining an average temperature of the target tissue over several minutes at or below a predetermined temperature so as not to destroy or permanently damage the target tissue.

A process for heat treating biological tissue includes repeatedly applying a pulsed energy to a target tissue over a period of time so as to controllably raise a temperature of the target tissue to create a therapeutic effect to the target tissue without destroying or permanently damaging the target tissue. After the first treatment is concluded the application of the pulsed energy to the target tissue is halted for an interval of time. Within a single treatment session a second treatment is performed on the target tissue after the interval of time by repeatedly reapplying the pulsed energy to the target tissue so as to controllably raise the temperature of the target tissue to therapeutically treat the target tissue without destroying or permanently damaging the target tissue.

A system for generating light radiation to neutralize microorganisms comprises a light source for emitting a light radiation, storage means with one or more unique identification codes, each of which is associated with a respective microorganism, and at least one respective wavelength range associated with said microorganism, and a logic control unit. The logic control unit is configured to select a wavelength range based on the microorganism to be neutralized, activate the light source in such a way that light radiation emitted by said light source has a wavelength within said selected wavelength range, so that, when the system is in use, the light radiation induces optical resonance in the microorganism, causing denaturation of genetic patrimony of the microorganism.

A present idea relates to a device to kill micro-organisms inside the patient's respiratory tract using UV light, specifically UV-C. It is particularly used to treat patients with Coronaviruses family such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). The device consists of a triple-lumen catheter and UV control unit. The distal end of one of the catheter's lumen has a curved UV chamber while the proximal end has a cable with a socket to be connected to the UV control unit. The second lumen of the catheter is used for oxygen supply, and the third lumen of the catheter is used for suction.

Systems and methods are provided for treating or preventing carbon monoxide poisoning. In particular, systems and methods are provided for a phototherapy treatment or prevention system that delivers light radiation to a patient's body to photodissociate carbon monoxide from hemoglobin.

Systems and method relate to administering phototherapy. A device includes a hollow structure having at least a first open end. The hollow structure includes a rotatable member, one or more coherent light generators, and, for each coherent light generator, one or more lenses or mirrors optically connected to the coherent light generator and configured to alter at least one aspect of a beam of coherent light. The device further includes a processing circuit including a processor and a memory storing instructions. The instructions, when executed by the processor, cause the processor to accept an input from an operator and generate one or more beams of coherent light according to a plurality of settings configured to produce a therapeutic effect at a targeted treatment site. Additionally, the rotatable member is configured to be rotated to direct the one or more beams of coherent light to the targeted treatment site.