A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.

A bandage and a method of treating a wound with the bandage is provided. The method includes the steps of applying a photosensitive dye to the wound; covering the wound with a bandage; and applying a light to the dye such that the dye generates a reactive oxygen species.

Systems for enabling delivery of very high peak power laser pulses through optical fibers for use in ablation procedures preferably in contact mode. Such lasers advantageously emit at 355 nm wavelength. Other systems enable selective removal of undesired tissue within a blood vessel, while minimizing the risk of damaging the blood vessel itself, based on the use of the ablative properties of short laser pulses of 320 to 400 nm laser wavelength, with selected parameters of the mechanical walls of the tubes constituting the catheter, of the laser fluence and of the force that is applied by the catheter on the tissues. Additionally, a novel method of calibrating such catheters is disclosed, which also enables real time monitoring of the ablation process. Additionally, novel methods of protecting the fibers exit facets are disclosed.

A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.

A process for heat treating biological tissue includes providing a plurality of energy emitters formed into an array. Treatment energy in the form of ultrasound energy is generated from the plurality of emitters and applied to target tissue. The treatment energy has energy and application parameters selected so as to raise the target tissue temperature sufficiently to create a therapeutic effect while maintaining an average temperature of the target tissue over several minutes at or below a predetermined temperature so as not to destroy or permanently damage the target tissue.

A soft, stretchable, multifunctional bioelectronic interface can be used to monitor and/or modulate an entire organ, such as a stomach, heart, bladder, or spinal cord. The interface's softness translates to reduced mechanical mismatch with the tissue, and the interface's stretchability reduces interfacial stress with dynamically expanding and contracting organs. The electronics are stretchable thanks in part to liquid-metal conductors sealed within hollow channels of elastomeric fibers embedded in the interface. The liquid metal is largely strain-insensitive, non-toxic, and has a melting point of less than 37° C., so it remains liquid when implanted in a mammalian body. The liquid metal conductors connect microelectronic components, such as micro light-emitting diodes (μLEDs), electrodes, photodiodes, and temperature sensors, to a flexible printed circuit board (fPCB) at one end of the fiber. The interface may include other microelectronic components, such as piezoelectric strain sensors, that are also coupled to the fPCB.

A retinal phototherapy or photostimulation system includes a laser console generating at least one treatment beam having parameters to photostimulate or treat, while not permanently damaging, a retinal target tissue. The parameters of the at least one treatment beam are fixed so as not to be alterable by a medical provider. A projector or camera projects the at least one treatment beam onto at least a portion of the retina, and a scanning mechanism controllably directs the at least one treatment beam to treatment areas of the retina.

A light emitting type capsule treatment tool for irradiating light with a specific wavelength required for photoimmunotherapy, includes a power receiving coil, a magnetic member, a light emitting member and a capsule. The power receiving coil is formed by winding a conductive wire and configured to receive electric power supplied from an external transmission antenna via a magnetic flux. The magnetic member is placed on an inner circumference of the power receiving coil. The light emitting member is configured to be supplied with electric power from the power receiving coil and to emit the light with the specific wavelength. The capsule houses the power receiving coil, the magnetic member and the light emitting member.

A phototherapy device includes: a treatment light emitter configured to emit treatment light for causing a reaction of a drug; a narrow band light emitter configured to emit narrow band light having part of wavelength band of a visible light range; an imager configured to obtain a narrow band light image which is formed using the narrow band light applied onto an application position of the treatment light; a narrow-band-light image variation calculator configured to calculate a time variation between the narrow band light image obtained before an application of the treatment light and the narrow band light image obtained after the application of the treatment light; and a display image generator configured to generate a display image including information based on the calculated variation.

A phototherapy device includes: a treatment light emitter configured to emit treatment light for causing a reaction of a drug; a first imager configured to obtain a tissue structure image which is formed using narrow band light applied onto an application position of the treatment light; a second imager configured to obtain a fluorescence image which is formed using excitation light applied onto the application position of the treatment light; a boundary region calculator configured to refer to the tissue structure image to determine a boundary region in which a tissue structure has changed; a fluorescence intensity variation calculator configured to calculate magnitude of variation in fluorescence intensity of the boundary region; and a display image generator configured to generate a display image to be used for displaying the magnitude of variation of the fluorescence intensity.