A method for treating pelvic pain and or chronic prostatitis, and or overactive bladder symptoms. Energy, preferably in the form of infrared or near infrared wavelength light may be applied across the vaginal tissue or rectal tissue to treat pelvic pain and or chronic prostatitis. This method of energy application may cause local heating, alteration of cellular respiration, and alterations of local blood flow resulting in decreased muscle spasm, and or decreased pain, and or decreased overactive bladder symptoms. The method of the present invention may effectively treat chronic pelvic pain and or the symptoms of chronic prostatitis. The method of the invention may combine massaging of tissue with irradiation of same.

The present invention provides an optical probe system that allows for determination of optical properties at the wall of a hollow cavity and photosensitizer uptake at the time of photodynamic therapy (PDT). In one embodiment, this system provides for rigorous treatment planning to maximize efficacy and minimize risk to patients by optimizing the concentration of the scattering emulsion infused into the cavity and the delivered laser power.

Methods for improving transmucosal delivery of Photobiomodulation to the body of a patient. Near infrared energy can be delivered through natural body openings in order to deliver therapeutic irradiance to deep tissues and organs. The use of a double sheath mechanism of energy introduction may decrease the discomfort associated with the present method of delivery among those patients with allodynia or severe hyperalgesia. Energy device power settings can be further optimized to improve outcomes and decrease the incidence of known adverse events. Furthermore, the availability of intuitive large screen user interfaces provides a unique opportunity to gather real-time, real-world patient experience (RWE) data.

An apparatus for irradiating inside an object is disclosed, including a lumen having a longitudinal axis; optical fibers within the lumen and aligned with the longitudinal axis; and an illumination member moveable or fixed within the lumen along the longitudinal axis. The apparatus can be used in a method for irradiating inside an object, including the steps of: providing an object having a cavity defined by an internal surface; inserting the lumen into the cavity; activating the illumination member to irradiate the internal surface with emitted light; receiving in each of the optical fibers light redirected from the internal surface; conveying the redirected light in a proximal direction through the plurality of optical fibers; and analyzing the redirected light conveyed through the plurality of optical fibers.

A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.

A phototherapy device includes: a tubular first sheath having a transparent portion transmitting light; a tubular second sheath disposed in the first sheath, formed of a light-impermeable material, and having a light transmission region in a portion of a side wall thereof; a tubular third sheath disposed in the second sheath, formed of a light-impermeable material, and having a light transmission region in a portion of a side wall thereof; and an optical fiber passing through insides of the second and third sheaths in a longitudinal direction and emitting light in radial directions of the second and third sheaths, wherein the second and third sheaths are configured to perform at least one of relative rotation and relative movement, and wherein the light transmission regions of the second and third sheaths are configured to be overlapped by means of the relative rotation or the relative movement.

Systems for enabling delivery of very high peak power laser pulses through optical fibers for use in ablation procedures preferably in contact mode. Such lasers advantageously emit at 355 nm wavelength. Other systems enable selective removal of undesired tissue within a blood vessel, while minimizing the risk of damaging the blood vessel itself, based on the use of the ablative properties of short laser pulses of 320 to 400 nm laser wavelength, with selected parameters of the mechanical walls of the tubes constituting the catheter, of the laser fluence and of the force that is applied by the catheter on the tissues. Additionally, a novel method of calibrating such catheters is disclosed, which also enables real time monitoring of the ablation process. Additionally, novel methods of protecting the fibers exit facets are disclosed.

Systems for enabling delivery of very high peak power laser pulses through optical fibers for use in ablation procedures preferably in contact mode. Such lasers advantageously emit at 355 nm wavelength. Other systems enable selective removal of undesired tissue within a blood vessel, while minimizing the risk of damaging the blood vessel itself, based on the use of the ablative properties of short laser pulses of 320 to 400 nm laser wavelength, with selected parameters of the mechanical walls of the tubes constituting the catheter, of the laser fluence and of the force that is applied by the catheter on the tissues. Additionally, a novel method of calibrating such catheters is disclosed, which also enables real time monitoring of the ablation process. Additionally, novel methods of protecting the fibers exit facets are disclosed.

A urolithiasis removing device according to one embodiment can comprise: an insertion tube; a guide which is inserted into the insertion tube and which is relatively movable with respect to the insertion tube; a wire which is inserted into the guide and which is relatively movable with respect to the guide; a basket positioned in front of the wire and capable of holding urolithiasis; and a control unit for determining the size of the urolithiasis on the basis of the relative movement of the guide with respect to the insertion tube or the relative movement of the wire with respect to the guide.

A light radiating unit provided at a distal end portion of an optical fiber includes a first light radiating unit having a predetermined length in a longitudinal direction and capable of radiating therapeutic light having first intensity and a second light radiating unit connected consecutively to the first light radiating unit in the longitudinal direction and configured to radiate therapeutic light having second intensity lower than the first intensity. Consequently, even when a bladder, which is a hollow organ, and a urethra, which is a conduit, are irradiated with the therapeutic light at a time, intensity of the therapeutic light with which surfaces (inner wall surfaces) of respective parts are irradiated is equalized.