The newly discovered retinal ganglion cell photoreceptor melanopsin absent in the central fovea of the eye but distributed throughout the remaining human retinal body provides both non-visual biological/physiological input inducing circadian entrainment, and visual input affecting perceived brightness; this perceived brightness is not the object brightness commonly associated with luminance and perceived color of an object in central view, but the perception of brightness of a whole space or task background. Discussed are improvements to circadian lighting systems based on melanopsin stimulation whereby ambient and/or device background lighting may be temporally tuned over a range of prescribed color temperatures from a first subset of lighting having a higher melanopic content to a second subset of lighting having a lower melanopic content or vice versa in accordance with a desired circadian cycle, and in a manner where net light output is of a constant perceived brightness and color throughout temporal tuning.

An implantable device for implantation in a human body or animal body. The device includes an energy source, an energy storage device, and an electronics unit. Further, an actuator is coupled with the energy storage device and it is configured to emit electromagnetic waves by discharging the energy storage device.

The present disclosure provides a method and a system for treating a tissue using photodynamic therapy (PDT). A photosensitizer is administered to the tissue and one or more optical fibers are placed in the tissue. A treatment light is applied to the tissue by way of the one or more optical fibers. A temperature of the tissue is measured during application of the treatment light, and a fluence rate of the treatment light is modified based on the temperature of the tissue. For example, the fluence rate may be modified to be lower if the temperature of the tissue is higher than a predetermined threshold.

A therapeutic light delivery apparatus and method are disclosed. The apparatus includes a light source, a plurality of light emitting devices paired with a plurality of light detecting devices, wherein each of the light emitting devices is in optical communication with a channel of a delivery optical switch and each of the plurality of light detection devices is in optical communication with a channel of a detection optical switch. The plurality of light emitting devices are fixedly positioned within an applicator light flap. The system further includes an optical detector in optical communication with the detector optical switch. The system further includes an opto-electronic controller that controls delivery optical switch, the detector optical switch and the light source.

Light stimulation systems and methods for elevating testosterone levels in male patients.

A light source (2) including a plurality of LEDs (4); a light detector (3) that detects intensity of light emitted by the plurality of LEDs (4) as light intensity distribution of light emitted by the light source (2); and a light intensity distribution control circuit (6) that controls current, by which each of the plurality of LEDs (4) is driven, such that the intensity of the light emitted by each of the plurality of the LEDs (4), which is detected by the light detector (3), falls within a predetermined range.

A light-monitoring apparatus includes a power source, a light detector, a computer processor coupled with the power source and in communication with the light detector and configured to receive and record light exposure detected by the light detector, an output device coupled with the computer processor, and a computer-readable medium coupled with the computer processor and storing instruction code for summing the recorded light exposure from the computer processor over time and communicating a signal to the output device to generate and communicate a signal indicating that a cumulative threshold light exposure for achieving a health benefit has been reached. The apparatus can accordingly be used by an individual to monitor cumulative light exposure from both natural and artificial sources, e.g., in the treatment of seasonal or non-seasonal depression.

A treatment support system is provided with an irradiation unit for irradiating a medical agent containing a fluorescent material with treatment light, a light detection unit for detecting, out of the treatment light and fluorescence, at least the fluorescence, a storage uni, and a control unit. The control unit performs control of at least a start of storing the fluorescence signal by the storage unit based on that the fluorescence signal detected by the light detection unit has changed beyond at least a predetermined degree of change; or that the light detection unit has detected the signal of the treatment light.

Phototherapy systems comprising a therapeutic lamp platform for radiant lamps such as LEDs disposed in an assembly comprising a first wall to which the lamps are affixed thereto and a second wall, closer to the patient, spaced from the first wall wherein the lamps are recessed relative thereto. The second wall comprises a reflective surface facing towards a patient and a plurality of light apertures substantially aligned with the LEDs on the first wall for communicating lamp radiation from the lamps to a user. The lamps and associated circuitry are disposed between the first and second wall so that the reflective surface is relatively smooth and seamless towards the patient. The walls may include an eye slot. The device is mounted to the user with a frame comprising an eyeglass frame or goggles including lenses for shielding the user's eyes from lamp radiation.

A system for influencing a state of a user including a light source for emitting light influencing the state of the user and a light controller selectively controlling the emission of the light. The emission may include at least one of, the spectrum of said light; the duration of said light; the distribution of said light; the intensity of said light; and the timing of said light. The analysis engine provides a signal to the light controller indicating a desired emission of the light.