Computerized information processing methods for processing data from a medical device, such as an ingestible probe. In one embodiment, the method includes processing data obtained by the probe so as to produce a plurality of image frames, and further processing the frames to identify a plurality of frames of potential interest to a reviewer, and using the identified frames to form a preview of the entire data set. In one implementation, the processing of the data includes identification of one or more artifacts or shapes within the data associated with a medical condition, and selection of the frames for the preview includes those frames with the identified artifacts or shapes.

An improved device which is introduced into the intestinal tract of a living organism and which operates autonomously therein, adapted to deliver one or more therapeutic agents. In one embodiment, the probe communicates wirelessly with a portable electronic device outside the organism in order to receive commands to deliver the therapeutic agent, or perform other functions while the probe is within the intestinal tract.

Computerized information processing methods for processing data from a medical device, such as an ingestible probe. In one embodiment, the method includes processing data obtained by the probe so as to produce a plurality of image frames, and further processing the frames to identify a plurality of frames of potential interest to a reviewer based on at least an evaluation of portions of the frame(s) such as pixels or groups of pixels, and using the identified frames to form a preview of the entire data set. In one implementation, the processing of the data includes processing of pixel intensity and/or color (which can be correlated to various physiologic conditions) to help identify the frames of potential interest.

A method and system may include a therapeutic agent having a radioactive source enclosed by a container. The container may be placed within a cavity of a medical device for treating animal tissue. The method and system allows a radioactive source to be manufactured in such a manner so as to control and spatially modulate the delivery of radiation doses to a treatment area of animal tissue, such as for tissue of humans. From the container, radiation doses and/or a radiation field are produced by the radiation source. The geometry and size of the radiation doses are controlled by the geometry of the container and the geometry of the radiation source as well as the type, number, and geometry of holes/slots in either the source material and/or a surface of the container.

Computerized information acquisition and processing apparatus. In one embodiment, the apparatus includes an ingestible (e.g., swallowable) computerized device that includes a video apparatus, digital processor apparatus, and a wireless interface. A non-ingestible portion of the system communicates with the ingestible device via the wireless interface and, using computer software and algorithms, processes video data generated by the ingestible device relating to the intestinal tract of a living subject, so as to enhance the speed and/or accuracy of review by a physician or other individual. In one variant, the algorithmic processing by the non-ingestible apparatus includes one or more of: (i) color intensity analysis; (ii) artifact shape analysis; and/or (iii) inter-frame similarity analysis. In another variant, the ingestible device is configured to compress the data using the processor apparatus prior to transmission over the interface to conserve wireless bandwidth.

Systems and methods for rotating shield brachytherapy. In an aspect, some of the systems and methods can be used to facilitate shield selection for use in rotating shield brachytherapy. In an aspect, the invention is a shielded needle or catheter system with a rotational controller for delivering radioisotope-based interstitial rotating shield brachytherapy (I-RSBT). In an aspect, the catheter system can utilize paddle-based RSBT. Further provided are methods and systems for helical RSBT.

This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device includes a stent having a first strut. The first strut may include an inner surface and an outer surface. The medical device may also include a first attachment member coupled to the strut and a radioactive element. The radioactive element may be coupled to the attachment member.

The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

This disclosure provides design, material, preparation methods, and use alternatives for medical devices. An example stent includes an expandable framework and a plurality of tubular members disposed along the expandable framework. Each of the plurality of tubular members include a lumen extending therein. The example stent also include a coating, wherein the coating is applied directly to both the plurality of tubular members and the expandable framework.

This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device includes a stent having a plurality of longitudinally extending filaments. The stent also has an inner surface and an outer surface and a plurality of tubular members extending along the stent. Each of the plurality of tubular members is coupled with one or more of the plurality of longitudinally extending filaments and each of the plurality of tubular members is configured to accept a radioactive element, a spacer or both.