Methods for setting up, maintaining and operating a radiopharmaceutical infusion system, that includes a radioisotope generator, are facilitated by a computer of the system. The computer may include pre-programmed instructions and a computer interface, for interaction with a user of the system, for example, in order to track contained volumes of eluant and/or eluate, and/or to track time from completion of an elution performed by the system, and/or to calculate one or more system and/or injection parameters for quality control, and/or to perform purges of the system, and/or to facilitate diagnostic imaging.

The present disclosure discloses a boron neutron capture therapy system comprising: a boron neutron capture therapy device and an -amino acid-like boron trifluoride compound having a structure shown as formula (I) below:

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Wherein: R is selected from hydrogen, methyl, isopropyl, 1-methylpropyl, 2-methylpropyl, hydroxymethyl, 1-hydroxyethyl, benzyl or hydroxybenzyl; M is H or metal atom. The energy generated from the action of the neutron beam generated by the boron neutron capture therapy device on the -amino acid-like boron trifluoride compound destroys tumor cell DNA. In another aspect, the present disclosure discloses a use of an -amino acid-like boron trifluoride compound in the preparation of a medicament for tumor therapy.

Real-time X-ray dosimetry sensing in intraoperative radiation therapy (IORT). According to one aspect, a treatment head comprises at least one X-ray component configured to facilitate generation of therapeutic radiation in the X-ray wavelength range. A resilient balloon is disposed over the treatment head and configured for receiving therein a fluid to facilitate X-ray treatment of a tumor cavity. A plurality of X-ray sensing elements is disposed at a plurality of locations distributed on the interior or exterior of the resilient balloon and configured for sensing X-ray radiation emanating from the treatment head. A control system is provided that is responsive to data received from the X-ray sensing elements to determine a magnitude of X-ray radiation detected at each of the X-ray sensing elements.

Methods for setting up, maintaining and operating a radiopharmaceutical infusion system, that includes a radioisotope generator, are facilitated by a computer of the system. The computer may include pre-programmed instructions and a computer interface, for interaction with a user of the system, for example, in order to track contained volumes of eluant and/or eluate, and/or to track time from completion of an elution performed by the system, and/or to calculate one or more system and/or injection parameters for quality control, and/or to perform purges of the system, and/or to facilitate diagnostic imaging.

The present invention provides balloon catheters and methods for using the same. Unlike existing balloon catheters in the art, the present balloon catheters expand in the proximal direction to enhance fit. The balloon catheters include sliding balloon catheters, preformed balloon catheters, super-elastic balloon catheters, and may be augmented with peripheral catheters.

A radiotherapy method for treatment of skin includes the step of applying radiation to a first region of interest of a person's skin using a radiotherapy device including a first filter having a first thickness and a first applicator having a first length. A flow of desired photons emitted from an x-ray tube of the radio therapy device is increased by (a) replacing the first applicator with a second applicator having a second length shorter than the first length, replacing the first filter with a second filter having a second thickness greater than the first thickness, and using a first dose rate less than one thousand centigray per minute, or (b) replacing the first applicator with the second applicator, using a third filter having a third thickness less than or equal to the first thickness, and using a second dose rate greater than one thousand centigray per minute.

A medical device includes: a base; a positioner coupled to the base; an accelerator coupled to the positioner, wherein the positioner is operable to rotate the accelerator relative to the base about at least two axes; and a power source coupled to the accelerator, the power source configured to provide microwave power for the accelerator, wherein a position of the power source relative to the base remains fixed during movement of the accelerator. A medical device includes: a base; a positioner coupled to the base; an accelerator coupled to the positioner; a power source configured to provide microwave power for the accelerator, wherein a position of the source relative to the base remains fixed during movement of the accelerator; and a waveguide for coupling the power source and the accelerator; wherein the waveguide has a first segment with a first cross section, the first cross section being a circular cross-section.

This disclosure provides systems, methods, and apparatus related to laser plasma accelerators. In one aspect a block of material defines a gas inlet, a chamber in fluid communication with the gas inlet, a throat in fluid communication with the chamber, a channel in fluid communication with the throat, and a gas outlet in fluid communication with the channel. The throat is configured to generate a supersonic flow of a gas when the gas flows through the throat. The channel includes a ramp that is positioned proximate the gas outlet, with the ramp being inclined at an angle with respect to a direction of a flow of the gas proximate a surface of the channel prior to the ramp at the gas outlet.

Methods for setting up, maintaining and operating a radiopharmaceutical infusion system, that includes a radioisotope generator, are facilitated by a computer of the system. The computer may include pre-programmed instructions and a computer interface, for interaction with a user of the system, for example, in order to track contained volumes of eluant and/or eluate, and/or to track time from completion of an elution performed by the system, and/or to calculate one or more system and/or injection parameters for quality control, and/or to perform purges of the system, and/or to facilitate diagnostic imaging.

Provided herein is a light transmitting cable for laser treatment, the cable including a first optical fiber configured to generate a high energy particle by a laser beam transmitted from a light source and to transmit the high energy particle to a target; and an image transmitting cable configured to transmit an image surrounding the target, thereby being capable of treating a tumor with relatively low power output while identifying a location of the tumor.