A method of real-time markerless measurement and calibration of a patient positioning system includes computing a three dimensional point cloud representation of a patient by using a camera to obtain depth points of the patient, where the z-direction corresponds to a direction along the focal length of the camera, demanding a z-limit that corresponds to a lower (z-min) and an upper (z-max) specification, computing a point cloud covariance and a point cloud mean for an optimized principle components analysis to compute a torso topography of the patient, determining a center point of the point cloud as an anchor measurement region and using the camera to determine a distance to the patient to establish an angle between a patient torso and a vector that is perpendicular to the camera, averaging the depth measurements in reference regions and compensating for parallax error in real-time during a calibration measurement or radiotherapy treatment plan.

Disclosed is a computer-implemented method for determining the pose of an anatomical body part of a patient's body for planning radiation treatment, a corresponding computer program, a non-transitory program storage medium storing such a program and a computer for executing the program, as well as a system for determining the pose of an anatomical body part of a patient's body for planning radiation treatment, the system comprising an electronic data storage device and acquire surface tracking data the aforementioned computer.

A method may include acquiring a first image including a target point and a first reference point, the target point corresponding to at least one part of a subject, the first reference point corresponding to a first marker disposed on the couch of the medical device; determining a first spatial position of the first marker, the first spatial position corresponding to a first working position of the couch; determining a first spatial position of the at least one part of the subject based on the first image and the first spatial position of the first marker; determining a second spatial position of the first marker, the second spatial position corresponding to a second working position of the couch; determining a second spatial position of the at least one part of the subject based on the second spatial position of the first marker and the first spatial position of the at least one part of the subject. In some embodiments, the method may further include adjusting the second working position of the couch based on the second spatial position of the at least one part of the subject.

The invention comprises a system for controlling a charged particle beam shape and direction relative to a controlled and dynamically positioned patient and/or an imaging surface, such as a scintillation plate of a tomography system and/or a first two-dimensional imaging system coupled to a second two-dimensional imaging system. Multiple interlinked beam/patient/imaging control stations allow safe zone operation and clear interaction with the charged particle beam system and the patient. Both treatment and imaging are facilitated using automated sequences controlled with a work-flow control system.

Disclosed herein are systems and methods for real-time monitoring of patient position and/or location during a radiation treatment session. Images acquired of a patient during a treatment session can be used to calculate the patient's position and/or location with respect to the components of the radiation therapy system. One variation of a radiation therapy system includes a circular gantry with a rotatable ring coupled to a stationary frame, a therapeutic radiation source mounted on the rotatable ring, and a patient-monitoring imaging system mounted on the rotatable ring. The patient-monitoring system may have one or more image sensors or cameras disposed on the rotatable ring within a bore region of the radiation therapy system, and may be configured to acquire image data as the ring rotates.

A scintillation material is longitudinally packaged in a circumferentially surrounding sheath, where the sheath has a lower index of refraction than the scintillation material, to form a scintillation optic or scintillation fiber optic. The scintillation material yields secondary photons upon passage of a charged particle beam, such as a positively charged residual particle beam having transmitted through a sample. The internally generated secondary photons within the sheath are guided to a detector element by the difference in index of refraction. Multiple scintillation optics are assembled to form a two-dimensional scintillation array coupled to a two-dimensional detector array, such as for use in determination of state of the residual charged particle beam, determination of an exit point of the particle beam from the sample, path of the treatment beam, and/or tomographic imaging.

The present invention relates to correlating a position of a radiation beam with a position of a target to be irradiated which is contained in a structure having a repetitive motion comprising a plurality of successive motion cycles. External position data is acquired, which describes a position the structure during different motion cycles and/or time periods. Target data is acquired, which describe a position of the target during the motion cycles and/or time periods. A correlation model is generated, which correlates the external position and the target position. A predicted target position during a motion cycle is determined based on the correlation model and acquire external position data. Primary verification data is determined that describes an difference between actual and predicted target position. When the prediction is accurate, a further prediction and verification of the target position in later motion cycles can be performed.

A patient-positioning system for radiotherapy is provided. The system includes a processing device and a storage device. The processing device loads a program from the storage device to execute a control module, a positioning room module, and a treatment room module. The control module obtains treatment planning data. The positioning room module calculates the second support displacement of the fulcrum through image registration based on the tilt angle, rotation angle, target displacement, original target point cloud, and a reference displacement. The treatment room module drives the mechanical device to move the treatment room table such that the fulcrum is at the second support displacement relative to the beam exit.

A system for radiation therapy may obtain a plurality of sets of motion data each of which corresponds to one of a plurality of motion phases of a subject. A set of motion data corresponding to a motion phase may include first physiological motion data and second physiological motion reflecting a physiological motion during the motion phase. The first physiological motion data and the second physiological motion data may be collected via a medical imaging device and a first motion sensor, respectively. The system may also direct a radiotherapy device to deliver a radiation treatment to the subject according to a treatment plan. During the radiation treatment, the system may obtain target physiological motion data reflecting the physiological motion of the subject, the target physiological motion data being collected via a second motion sensor; and adjust the treatment plan to adapt to the physiological motion of the subject.

Disclosed herein are systems and methods for real-time monitoring of patient position and/or location during a radiation treatment session. Images acquired of a patient during a treatment session can be used to calculate the patient's position and/or location with respect to the components of the radiation therapy system. One variation of a radiation therapy system includes a circular gantry with a rotatable ring coupled to a stationary frame, a therapeutic radiation source mounted on the rotatable ring, and a patient-monitoring imaging system mounted on the rotatable ring. The patient-monitoring system may have one or more image sensors or cameras disposed on the rotatable ring within a bore region of the radiation therapy system, and may be configured to acquire image data as the ring rotates.