A radiotherapy apparatus for an animal comprises a treatment part including an accommodation space for placing an animal, an irradiation part including an electron generator and a linear accelerator coupled to one side of the electron generator and disposed in a direction perpendicular to the treatment part, the linear accelerator being configured to emit radiation toward the treatment part, and an image acquisition part located at a preset interval from the treatment part along an irradiation direction of the radiation and configured to obtain an image of an irradiation area when the radiation is applied, wherein the radiation has an output of 1 MeV to 2 MeV so as to be applied to a diseased part located within a predetermined distance range from epidermis of the animal.

Disclosed herein are methods for radiotherapy treatment plan optimization for irradiating one or more target regions using both an internal therapeutic radiation source (ITRS) and an external therapeutic radiation source (ETRS). One variation of a method comprises iterating through ITRS radiation dose values and ETRS radiation dose values to attain a cumulative dose that meets prescribed dose requirements. In some variations, an ITRS is an injectable compound that has a targeting backbone and a radionuclide, and images acquired using an imaging compound that has the same targeting backbone as the injectable compound can be used to calculate the radiation dose deliverable using the injectable ITRS, and also to calculate firing filters for delivering radiation using a biologically-guided radiation therapy (BGRT) system. Image data acquired from a previous treatment session may be used to adapt the dose provided by an ITRS and/or ETRS for a future treatment session.

A method for radiation therapy treatment verification includes acquiring: treatment plan information from a radiation therapy system; patient image data; and transit image data received from an electronic portal imaging device during radiation therapy. The treatment plan information is divided into a plurality of segments. Predicted segment image data is determined utilizing a predicted image calculation algorithm and at least the patient image data and the treatment plan information. A predicted integrated image is determined through superposition of the predicted segment image data. Measured segment responses are determined from the transit image data utilizing the predicted segment image data and the predicted integrated image. The measured segment responses are converted to measured segment doses. A measured dose map having a sum of the measured segment doses is compared to a planned dose map based on the treatment plan information to assess radiation treatment delivery.

An apparatus for visualizing a movable radiation source, the apparatus comprising: a radiation angular position sensor arranged for generating an angular position, with respect to a sensor axis, of a radiation source emitting radiations in front of said radiation angular position sensor; a camera having a camera axis distinct from the sensor axis; a light diverter arranged in front of said radiation angular position sensor for diverting toward the camera, light originally emitted in front of said radiation angular position sensor toward the radiation angular position sensor, the light diverter being arranged to not change the direction of radiations emitted in front of said radiation angular position sensor; and a composite image generator arranged for adding to a camera image captured by the camera a radiation source marker at a position derived from said angular position and automatically scaled to the camera image size and resolution.

Techniques are described to simulate partial patient images, such as 2D Megavolt (MV) images or 2D CT images, such as slices or projections, as the patient representation evolves during the radiation treatment, and then compare one or more actual patient images obtained during the radiation treatment to the one or more simulated partial patient images. A resulting image similarity indication, such as a pass/fail signal, can then be provided to a radiation therapy system to represent movement of the organ occurring during the radiation treatment.

A system and method of performing prospective and retrospective on-line adaptive radiotherapy. The method includes performing, during a treatment delivery session, delivery of a dose of radiation to an anatomical volume. The method includes detecting, during the treatment delivery session, a current state of the anatomical volume. The method includes predicting a future change in the current state of the anatomical volume during the treatment delivery session. The method includes adjusting, while the anatomical volume is in the current state, the treatment delivery to anticipate the future change in the anatomical volume.

A system and method of performing prospective and retrospective on-line adaptive radiotherapy. The method includes performing, during a treatment delivery session, delivery of a dose of radiation to an anatomical volume. The method includes detecting, during the treatment delivery session, a current state of the anatomical volume. The method includes predicting a future change in the current state of the anatomical volume during the treatment delivery session. The method includes adjusting, while the anatomical volume is in the current state, the treatment delivery to anticipate the future change in the anatomical volume.

Electromagnetic waves for an accelerating structure of the radiation delivery system are generated by a microwave source. The electromagnetic waves generated by the microwave source are adjusted by an energy adjuster to an imaging energy level. A kilovolt (kV) imaging beam is generated by the accelerating structure based on the imaging energy level. The electromagnetic waves generated by the magnetic source are adjusted by the energy adjuster to a treatment energy level. A megavolt (MV) treatment beam is generated by the accelerating structure based on the treatment energy level.

The present invention is a method or system for acceptance testing and commissioning of a LINAC and treatment planning system (TPS). For a LINAC commissioning, the present invention collects reference data from a fully calibrated LINAC and compares the reference data with machine performance data collected from LINAC. The compared results are analyzed to assess accuracy of the testing LINAC. For a TPS commissioning, the present invention collects standard reference data from standard treatment plans and standard input data and compares the standard reference data with results from standard tests that are performed by a testing treatment plan system. The compares results are analyzed to assess accuracy of the testing treatment plan system.

A computer program product, method, system and device that acquires, by a radiation detector, exit radiation measurement information during delivery of patient treatment. Patient anatomy information is also received and a radiation detector response calibration is determined utilizing at least the exit radiation measurement information, the patient anatomy information, and at least a portion of a radiation treatment plan.