The embodiments of the present disclosure provide a system for determining a radiation dose. The system may include: obtaining data related to radiation source, a radiation auxiliary image of a target object at a target radiation time point, and an initial fluence map corresponding to the target radiation time point; determining a target fluence map corresponding to the target radiation time point by one or more iterations based on the radiation auxiliary image, the initial fluence map, and the data related to radiation source; obtaining a target scanning image of the target object; and determining the radiation dose received by the target object at the target radiation time point, based on the target fluence map, the target scanning image, and the data related to radiation source.

A system and method for delivering microbeam radiation therapy (MRT) includes a computed tomography scanner (“CT”) configured to generate tomographic images of a subject, or patient, the scanner including an imaging apparatus, a gantry with an opening for positioning the patient therein, an axis of rotation around which the gantry rotates, and an x-ray source mounted to and rotatable with the gantry. The system includes a bed for patient positioning within the gantry opening and a multi-slit collimator removably mounted downstream of the x-ray source for delivering an array of microbeams of MRT to a targeted portion of the patient. Switching between MRT and CT is provided, and MRT modes of operation include a stationary mode, and continuous and step-wise rotational modes.

A medical imaging system a magnet unit includes a main magnet and a first housing. In an embodiment, the main magnet is arranged inside the first housing and includes coil elements and at least one coil carrier, the magnet unit defining an examination opening. The first radiation unit is embodied to irradiate the examination object and is arranged on the side of the magnet unit. The magnet unit includes a first region, transparent to radiation emitted by the first radiation unit radially to the examination axis. The first radiation unit is embodied to emit radiation through the first region of the magnet unit in a direction of the examination opening and is furthermore embodied to rotate about the examination opening.

An image calibration method includes capturing and correcting a flood field image for background signal and effects of known image-panel features (dead/bad pixels). The corrected image is processed to separate frequencies characteristic of relative pixel sensitivities from frequencies characteristic of radiation energy fluence. The incident energy fluence has a known maximum in-field energy fluence gradient. A model that describes the incident energy fluence on a detector is generated or received. The corrected image may be modeled at frequencies at or below the maximum in-field energy fluence gradient. A pixel sensitivity matrix (PSM) is generated by adjusting the corrected image with the model of the incident energy fluence on the detector. For example, the corrected image signal may be divided by the model or the model may be subtracted from the corrected image. The PSM may be used to correct additional raw images captured by the detector.

Systems and methods are provided for registering images. The systems and methods perform operations comprising: receiving, at a first time point in a given radiation session, a first imaging slice corresponding to a first plane; encoding the first imaging slice to a lower dimensional representation; applying a trained machine learning model to the encoded first imaging slice to estimate an encoded version of a second imaging slice corresponding to a second plane at the first time point to provide a pair of imaging slices for the first time point; simultaneously spatially registering the pair of imaging slices to a volumetric image, received prior to the given radiation session, comprising a time-varying object to calculate displacement of the object; and generating an updated therapy protocol to control delivery of a therapy beam based on the calculated displacement of the object.

Systems and methods for determining a radiation isocenter of a linear accelerator (LINAC). Determining the radiation isocenter may include determining a set of three-dimensional (3D) radiation beam axes of the LINAC from two-dimensional (2D) radiation transmission images. The radiation isocenter may be determined based on at least the set of 3D radiation beam axes. Determining the set of 3D radiation beam axes may including constructing a 3D radiation beam axis based on a determined location of a beam axis of a radiation beam generated with a gantry of the LINAC at an angle relative to a reference gantry angle, a determined center of a shadow of a radiation opaque marker in the radiation field of the radiation beam, and the gantry angle.

A tracking method, a tracking system, and an electronic device are provided. The tracking method includes: acquiring an actual scattering image of a target object at time i, where i is an integer greater than 0, and the actual scattering image is generated according to rays scattered by body tissue where the target object is located; processing the actual scattering image or a reference image corresponding to the actual scattering image with a preset model, and determining a location offset of the target object at the time i according to the processing result; and tracking the target object according to the location offset of at least one time. The preset model is indicative of a location conversion relationship of corresponding pixels in images that are formed before and after the rays are scattered.

The present invention relates to a computer-implemented medical method for monitoring a spatial position of a patient's body part, wherein at least one optimum spatial direction for a line of sight of a check x-ray-image is determined, that qualifies for quantifying a deviation of the spatial position of the patient's body part from a target spatial position for the patient's body part. The present invention further relates to a corresponding computer program and a corresponding medical system.

A radiation treatment session is initiated to deliver a therapeutic radiation beam from a therapeutic radiation source to a target. One or more X-ray radiation sources are caused to deliver an imaging radiation beam from the one or more X-ray radiation sources through the target to one or more X-ray detectors to acquire imaging data associated with the target during therapeutic radiation beam delivery. One or more volumetric images are constructed using the acquired imaging data.

An example computer-implemented method for tuning a beam spot in a radiation therapy system based on radiation field measurements has been disclosed. The example method includes configuring an electron beam to generate a first beam spot on an electron-beam target of the radiation therapy system, determining a value for one or more radiation field quality metrics for a first radiation beam that originates from the first beam spot, and based on the value, determining whether the first radiation beam is outside a specified quality range.