A computer-implemented method for calibrating a multi-leaf collimator of a radiotherapy device. The multi-leaf collimator comprises a plurality of leaves, each leaf comprising an imaging marker, wherein the radiotherapy device includes an imaging device configured to image the leaves. The method comprises: receiving, from the imaging device, an image of the multi-leaf collimator in a calibration position, wherein in the calibration position the tips of the leaves abut an edge of a rigid calibration block, the edge having a known calibration profile; calculating for each leaf, from the calibration profile and the location of the marker in the image, a minor offset of the marker relative to a reference point; and outputting calibration values based on the calculated minor offsets, wherein at least one leaf of the multi-leaf collimator is controlled based on the calibration values.

Disclosed is a medical system (100, 500) that comprises a radiotherapy system (102) configured for controllably irradiating a target volume (114) within an irradiation zone (112); a subject support (120) configured for supporting at least a ventral region (124) of a subject (122) within the irradiation zone; a breath monitor system (132, 132′) configured for providing a motion signal (154, 158) descriptive of subject breathing motion; and a subject display (130, 130′) configured for displaying a breathing phase indicator (160, 160′) to the subject when supported by the subject support. Execution of the machine executable instructions (150) causes a processor (142) controlling the medical system to receive (200) a time resolved magnetic resonance imaging dataset (152) synchronized to a measured motion signal (154). Execution of the machine executable instructions further causes the processor to repeatedly: determine (202) a desired motion signal (156) by temporally stepping through the measured motion signal; acquire (204) a current motion signal (158) using the breath monitor system; render (206) the breathing phase indicator on the display, wherein the breathing phase indicator is configured to indicate a difference (700) between the desired motion signal and the measured motion signal; and generate (208) control commands (162) configured for controlling targeting of the radio therapy system using a first portion of the time resolved magnetic resonance imaging dataset synchronized to the desired motion signal or a second portion of the time resolved magnetic resonance imaging dataset referenced by the current motion signal.

The present application relates to a radiotherapy apparatus for delivering radiation to a subject. The apparatus comprises a source of radiation configured to rotate about an isocenter and emit radiation in a radiation plane containing said isocentre. The apparatus also comprises a subject support surface including a portion configured to be located substantially at the isocenter. The subject support surface comprises a subject support surface rotation mechanism configured to rotate the subject support surface about an axis of rotation parallel to and spaced from an axis that passes through the isocenter. The subject support surface also comprises a first section configured to move from a first position to a second position along at least one of a longitudinal and lateral direction. The apparatus also comprises a processor configured to control the longitudinal and/or lateral movement of the first section as a function of the rotation of the subject support surface to maintain the portion of the subject support surface substantially at the isocenter.

Disclosed are a method of measuring concentration distribution of boron for boron neutron capture therapy (BNCT) using magnetic resonance imaging (MRI) alone and a treatment planning method for BNCT. The methods include (a) acquiring an anatomical image of a patient and measuring a boron concentration from magnetic resonance (MR) data, (b) extracting a boron concentration change prediction parameter of the patient and predicting the concentration over time, (c) calculating and verifying a boron distribution prediction value estimated by boron imaging and spectral analysis, and (d) deriving an optimal time for BNCT based on the verified results.

A radiotherapy device is disclosed. The radiotherapy device includes a radiation source, a detecting means and controller communicatively coupled to the radiation source and the detecting means. The radiation source is configured to generate a treatment beam for irradiating a subject. The detecting means is configured to detect a motion of the subject, the motion comprising a first physiological motion component and a second physiological motion component. The controller is configured to generate a beam shaping control signal based on the first physiological motion component and to generate a beam gating control signal based on the second physiological motion component

A phantom system is disclosed that includes a phantom and at least one removable phantom attachment configured to be attached to the phantom so that the phantom system may have an orientation, location and/or anthropomorphic feature identifiable to an imaging device.

Systems and methods may be used for estimating instantaneous patient motion (a patient state). The patient state may be estimated based on a 3D reference volume and a stream of images, for example from an image acquisition device. The stream of images may be received in real-time, for example during a radiation therapy treatment. An example method may include encoding the 3D reference volume using a 3D encoder branch of a patient state generator network, encoding the stream of images using a 2D encoder branch of the patient state generator network, and combining the encoded 3D reference volume and the encoded real-time stream of images. The method may include estimating a 3D spatial transform that maps the 3D reference volume to a current patient state by decoding the combined encoding using a 3D decoder branch of the patient state generator network.

Systems, methods, and computer software relating to gating using non-parallel imaging planes, determining accumulated dose to tissues during radiotherapy with actual beam delivery information, stopping/adjusting/reoptimizing therapy based on such accumulated doses and the generation and use of prognostic motion models and prognostic-motion adapted radiation treatment plans are disclosed.

The present disclosure relates to a cavity of a medical device. The cavity may include a bore and an accommodating cavity configured to provide an accommodating space for at least a portion of a couch in a radial direction of the bore. The accommodating cavity may be disposed on an inner wall of the bore and extend along an axial direction of the bore, and the accommodating cavity may be configured to form, with the bore, a connected space in which the at least a portion of the couch is allowed to move along an axial direction of the bore.

A radiation therapy medical apparatus is disclosed. The medical apparatus comprises: a base; a cylindrical gantry, peripherally and rotatably supported by the base; a radiation therapy assembly, comprising an arm and a radiation head, wherein one end of the arm is fixed to a first position on a first side of the gantry and the other end thereof is extended outwardly, and the radiation head is fixed to the other end of the arm; an imaging assembly, mounted to a second side of the gantry opposite to the first side, and configured to be a first balanced weight part for balancing the radiation therapy assembly; and a counterbalance, fixed to the second side of the gantry, and configured to cooperate with the imaging assembly to prevent the gantry from turnover under action of the radiation therapy assembly and configured to dynamically balance with the radiation therapy assembly with respect to a rotation axis of the gantry.